Standard name Systematic name Name description Description
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis Glucosyl hydrolase required for beta-1,6-glucan biosynthesis; type II integral membrane protein that localizes to ER, plasma membrane, sites of polarized growth and secretory vesicles; functionally redundant with Skn1p; KRE6 has a paralog, SKN1, that arose from the whole genome duplication
Visualize the interactome of KRE6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 24

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud NaN 0.053 NaN
Cytoplasm NaN 0.474 NaN
ER NaN 0.053 NaN
Mito NaN 0.158 NaN
Nucleus NaN 0.053 NaN
Vac/Vac Memb NaN 0.316 NaN

GFP localization & abundance

GFP localization GFP abundance
vacuole 4760

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KRE6 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0006 (1,6-beta-glucan synthase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SKN1 YGR143W Protein involved in sphingolipid biosynthesis genetic 5 3 4 Dosage Rescue, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
KEG1 YFR042W Integral membrane protein of the ER physical 3 2 3 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
LAS17 YOR181W Actin assembly factor physical 2 2 1 Affinity Capture-Western, Two-hybrid
MID2 YLR332W O-glycosylated plasma membrane protein genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OPI1 YHL020C Transcriptional regulator of a variety of genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Dosage Rescue
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Synthetic Lethality
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex physical 1 1 1 Affinity Capture-MS
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
CNB1 YKL190W Calcineurin B physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Affinity Capture-MS
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Two-hybrid
ROT1 YMR200W Molecular chaperone involved in protein folding in ER physical 1 1 1 Affinity Capture-Western
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Two-hybrid
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Synthetic Rescue
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
YDL206W YDL206W Putative protein of unknown function genetic 1 1 1 Synthetic Lethality
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Synthetic Lethality
RTN1 YDR233C Reticulon protein genetic 1 1 1 Synthetic Lethality
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Synthetic Lethality
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Synthetic Lethality
RPL1B YGL135W Ribosomal 60S subunit protein L1B genetic 1 1 1 Synthetic Lethality
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Synthetic Lethality
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
PUS5 YLR165C Pseudouridine synthase genetic 1 1 1 Synthetic Lethality
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Synthetic Lethality
PRM3 YPL192C Protein required for nuclear envelope fusion during karyogamy genetic 1 1 1 Synthetic Lethality
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Dosage Rescue
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Growth Defect
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Synthetic Growth Defect
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Synthetic Lethality
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein genetic 1 1 1 Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Synthetic Growth Defect
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Synthetic Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Synthetic Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Rescue
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Synthetic Lethality
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity genetic 1 1 1 Synthetic Growth Defect
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Synthetic Lethality
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Synthetic Lethality
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Dosage Rescue
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-Western
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Synthetic Lethality
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Phenotypic Enhancement
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Synthetic Lethality
CST26 YBR042C Acyltransferase genetic 1 1 1 Synthetic Lethality
FRD1 YEL047C Soluble fumarate reductase genetic 1 1 1 Synthetic Lethality
CWH41 YGL027C Processing alpha glucosidase I genetic 1 1 1 Synthetic Lethality
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Synthetic Growth Defect
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly physical 1 1 1 Affinity Capture-MS
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Synthetic Lethality
CNE1 YAL058W Calnexin physical 1 1 1 Affinity Capture-Western
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 1 1 1 Dosage Rescue