Standard name Systematic name Name description Description
SSA2 YLL024C HSP70 family ATP-binding protein HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation
Visualize the interactome of SSA2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.380 0.754 NaN
Cytoplasm 0.697 0.262 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 364000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SSA2 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 16 4 15 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
HSP82 YPL240C Hsp90 chaperone physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
HSF1 YGL073W Trimeric heat shock transcription factor physical 8 4 3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 7 2 5 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 5 3 4 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
GET2 YER083C Subunit of the GET complex genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 5 3 3 Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
FES1 YBR101C Hsp70 (Ssa1p) nucleotide exchange factor physical 4 2 3 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 4 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
SSA4 YER103W Heat shock protein that is highly induced upon stress genetic 3 2 3 Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement
SSA3 YBL075C ATPase involved in protein folding and the response to stress genetic 3 2 3 Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DIS3 YOL021C Exosome core complex catalytic subunit physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
GET1 YGL020C Subunit of the GET complex genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
VAC14 YLR386W Enzyme regulator physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 2 2 2 Co-purification, Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
YDJ1 YNL064C Type I HSP40 co-chaperone physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 2 2 Synthetic Lethality, Negative Genetic
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HSF1 YGL073W Trimeric heat shock transcription factor genetic 2 2 2 Synthetic Rescue, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
RPN10 YHR200W Proteasome polyubiquitin receptor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FTH1 YBR207W Putative high affinity iron transporter genetic 2 1 2 Negative Genetic, Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UGX2 YDL169C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
REC107 YJR021C Protein involved in early stages of meiotic recombination genetic 2 1 2 Negative Genetic, Negative Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 2 1 2 Positive Genetic, Positive Genetic
UFO1 YML088W F-box receptor protein physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 2 1 Negative Genetic, Positive Genetic
CDC73 YLR418C Component of the Paf1p complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MFT1 YML062C Subunit of the THO complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 2 1 1 Negative Genetic, Negative Genetic
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MSD1 YPL104W Mitochondrial aspartyl-tRNA synthetase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
CTF4 YPR135W Chromatin-associated protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SGT1 YOR057W Cochaperone protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SKG3 YLR187W Protein of unknown function physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SKI2 YLR398C Ski complex component and putative RNA helicase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HRB1 YNL004W Poly(A+) RNA-binding protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
YMR027W YMR027W A metal-dependent phosphatase, part of the DUF89 protein family physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
TOP1 YOL006C Topoisomerase I physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
TAZ1 YPR140W Lyso-phosphatidylcholine acyltransferase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA4 YER103W Heat shock protein that is highly induced upon stress physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
REV3 YPL167C Catalytic subunit of DNA polymerase zeta physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MSE1 YOL033W Mitochondrial glutamyl-tRNA synthetase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
NMT1 YLR195C N-myristoyl transferase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
PNP1 YLR209C Purine nucleoside phosphorylase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADA2 YDR448W Transcription coactivator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space physical 1 1 1 Affinity Capture-MS
RAX2 YLR084C Protein required for the maintenance of bud site selection physical 1 1 1 Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Synthetic Lethality
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Synthetic Growth Defect
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
RBG2 YGR173W Protein with a role in translation physical 1 1 1 Affinity Capture-Western
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-Western
FET5 YFL041W Multicopper oxidase physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 genetic 1 1 1 Negative Genetic
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Phenotypic Enhancement
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Phenotypic Enhancement
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
IMP4 YNL075W Component of the SSU processome physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 1 1 1 Affinity Capture-MS
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking physical 1 1 1 Affinity Capture-MS
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex physical 1 1 1 Affinity Capture-MS
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SEN54 YPL083C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription physical 1 1 1 Affinity Capture-MS
RBG1 YAL036C Member of the DRG family of GTP-binding proteins physical 1 1 1 Affinity Capture-Western
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
CIR2 YOR356W Putative ortholog of human ETF-dH genetic 1 1 1 Negative Genetic
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
FIN1 YDR130C Spindle pole body-related intermediate filament protein physical 1 1 1 Affinity Capture-Western
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 Affinity Capture-MS
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 Affinity Capture-MS
GID7 YCL039W Subunit of GID Complex that binds directly to central component Vid30p physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Affinity Capture-MS
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 Affinity Capture-MS
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor physical 1 1 1 Affinity Capture-MS
PBR1 YNL181W Putative oxidoreductase physical 1 1 1 Affinity Capture-MS
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 1 1 1 Affinity Capture-Western
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Reconstituted Complex
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Affinity Capture-MS
INA1 YLR413W Protein of unknown function physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
AIP5 YFR016C Protein that positively regulates actin assembly physical 1 1 1 Affinity Capture-MS
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
ATG20 YDL113C Sorting nexin family member genetic 1 1 1 Negative Genetic
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily physical 1 1 1 Two-hybrid
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
SAN1 YDR143C Ubiquitin-protein ligase physical 1 1 1 Affinity Capture-MS
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
CSC1 YLR241W Calcium permeable gated cation channel physical 1 1 1 Affinity Capture-MS
FMP10 YER182W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein physical 1 1 1 Affinity Capture-MS
IGO1 YNL157W Protein required for initiation of G0 program physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Protein-peptide
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Affinity Capture-MS
CLN3 YAL040C G1 cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-Western
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway physical 1 1 1 Affinity Capture-MS
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 1 1 1 Reconstituted Complex
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Affinity Capture-Western
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 1 1 1 Two-hybrid
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p physical 1 1 1 Two-hybrid
PCL8 YPL219W Cyclin physical 1 1 1 Two-hybrid
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
GNP1 YDR508C Broad specificity amino acid permease physical 1 1 1 Affinity Capture-MS
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
RBD2 YPL246C Possible rhomboid protease physical 1 1 1 Affinity Capture-MS
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
PRM9 YAR031W Pheromone-regulated protein physical 1 1 1 Affinity Capture-MS
ADP1 YCR011C Putative ATP-dependent permease of the ABC transporter family physical 1 1 1 Affinity Capture-MS
ADY3 YDL239C Protein required for spore wall formation physical 1 1 1 Affinity Capture-MS
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein physical 1 1 1 Affinity Capture-MS
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis physical 1 1 1 Affinity Capture-MS
ELO3 YLR372W Elongase physical 1 1 1 Affinity Capture-MS
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
MYO3 YKL129C One of two type I myosins physical 1 1 1 Affinity Capture-MS
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Affinity Capture-MS
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Affinity Capture-MS
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) physical 1 1 1 Two-hybrid
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 1 1 1 Affinity Capture-MS
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
SEC20 YDR498C Membrane glycoprotein v-SNARE physical 1 1 1 Affinity Capture-MS
SIP5 YMR140W Protein of unknown function genetic 1 1 1 Phenotypic Suppression
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-Western
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-Western
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform physical 1 1 1 Reconstituted Complex
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase physical 1 1 1 Protein-peptide
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Phenotypic Suppression
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Protein-peptide
YBR287W YBR287W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
UBX3 YDL091C Clathrin-coated vesicle component, regulator of endocytosis physical 1 1 1 Affinity Capture-MS
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity physical 1 1 1 Affinity Capture-MS
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Affinity Capture-MS
YPQ2 YDR352W Putative vacuolar membrane transporter for cationic amino acids physical 1 1 1 Affinity Capture-MS
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Affinity Capture-MS
YEF1 YEL041W ATP-NADH kinase physical 1 1 1 Affinity Capture-MS
YEL077C YEL077C Helicase-like protein encoded within the telomeric Y' element physical 1 1 1 Affinity Capture-MS
YPT31 YER031C Rab family GTPase physical 1 1 1 Affinity Capture-MS
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Affinity Capture-MS
YER158C YER158C Protein of unknown function physical 1 1 1 Affinity Capture-MS
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Affinity Capture-MS
YFR006W YFR006W Putative X-Pro aminopeptidase physical 1 1 1 Affinity Capture-MS
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l physical 1 1 1 Affinity Capture-MS
VAM7 YGL212W Vacuolar SNARE protein physical 1 1 1 Affinity Capture-MS
VRG4 YGL225W Golgi GDP-mannose transporter physical 1 1 1 Affinity Capture-MS
YGR016W YGR016W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
TDA3 YHR009C Putative oxidoreductase involved in late endosome to Golgi transport physical 1 1 1 Affinity Capture-MS
TOM71 YHR117W Mitochondrial outer membrane protein physical 1 1 1 Affinity Capture-MS
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p physical 1 1 1 Affinity Capture-MS
SYG1 YIL047C Plasma membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein physical 1 1 1 Affinity Capture-MS
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane physical 1 1 1 Affinity Capture-MS
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex physical 1 1 1 Affinity Capture-MS
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) physical 1 1 1 Affinity Capture-MS
YEH1 YLL012W Steryl ester hydrolase physical 1 1 1 Affinity Capture-MS
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
YLL058W YLL058W Putative protein of unknown function with similarity to Str2p physical 1 1 1 Affinity Capture-MS
YLR001C YLR001C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
THI73 YLR004C Putative plasma membrane permease physical 1 1 1 Affinity Capture-MS
VID22 YLR373C G-quadruplex (G4) DNA binding protein physical 1 1 1 Affinity Capture-MS
YML002W YML002W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YMD8 YML038C Putative nucleotide sugar transporter physical 1 1 1 Affinity Capture-MS
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor physical 1 1 1 Affinity Capture-MS
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 Affinity Capture-MS
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Affinity Capture-MS
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p physical 1 1 1 Affinity Capture-MS
YOL075C YOL075C Putative ABC transporter physical 1 1 1 Affinity Capture-MS
TIM18 YOR297C Component of the mitochondrial TIM22 complex physical 1 1 1 Affinity Capture-MS
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Affinity Capture-MS
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) physical 1 1 1 Affinity Capture-MS
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Affinity Capture-MS
SSO1 YPL232W Plasma membrane t-SNARE physical 1 1 1 Affinity Capture-MS
YOP1 YPR028W Reticulon-interacting protein physical 1 1 1 Affinity Capture-MS
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins physical 1 1 1 Affinity Capture-MS
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily physical 1 1 1 Affinity Capture-MS
YSW1 YBR148W Protein required for normal prospore membrane formation physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
TFB4 YPR056W Subunit of TFIIH complex physical 1 1 1 Affinity Capture-MS
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-Western
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
TIM44 YIL022W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-Western
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall physical 1 1 1 Affinity Capture-MS
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation physical 1 1 1 Affinity Capture-Western
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Dosage Rescue
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase physical 1 1 1 Affinity Capture-MS
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family physical 1 1 1 Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p physical 1 1 1 Affinity Capture-MS
SIP3 YNL257C Putative sterol transfer protein physical 1 1 1 Affinity Capture-MS
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
DFG5 YMR238W Putative mannosidase physical 1 1 1 Affinity Capture-MS
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 1 1 1 Affinity Capture-MS
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
BSD2 YBR290W Heavy metal ion homeostasis protein physical 1 1 1 Affinity Capture-MS
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Affinity Capture-MS
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel physical 1 1 1 Affinity Capture-MS
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Affinity Capture-MS
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Phenotypic Suppression
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 1 1 1 Affinity Capture-MS
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs physical 1 1 1 Affinity Capture-MS
CIT1 YNR001C Mitochondrial citrate synthase physical 1 1 1 Affinity Capture-MS
COQ3 YOL096C O-methyltransferase physical 1 1 1 Affinity Capture-MS
PDR11 YIL013C ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
CST26 YBR042C Acyltransferase physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
AIM45 YPR004C Putative ortholog of mammalian ETF-alpha physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase physical 1 1 1 Affinity Capture-MS
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases physical 1 1 1 Affinity Capture-MS
CUE1 YMR264W Ubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Synthetic Growth Defect
FPR2 YDR519W Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
IRC22 YEL001C Protein of unknown function physical 1 1 1 Affinity Capture-MS
MSC7 YHR039C Protein of unknown function physical 1 1 1 Affinity Capture-MS
PDR10 YOR328W ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
FTR1 YER145C High affinity iron permease physical 1 1 1 Affinity Capture-MS
PDR15 YDR406W Plasma membrane ATP binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
PGS1 YCL004W Phosphatidylglycerolphosphate synthase genetic 1 1 1 Synthetic Rescue
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 1 1 1 Affinity Capture-Western
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site physical 1 1 1 Affinity Capture-MS
CWH41 YGL027C Processing alpha glucosidase I physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PMS1 YNL082W ATP-binding protein required for mismatch repair physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RFS1 YBR052C Protein of unknown function physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
KIN82 YCR091W Putative serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
PHO90 YJL198W Low-affinity phosphate transporter physical 1 1 1 Affinity Capture-MS
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
PHO91 YNR013C Low-affinity vacuolar phosphate transporter physical 1 1 1 Affinity Capture-MS
ORM1 YGR038W Protein that mediates sphingolipid homeostasis physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MIC26 YGR235C Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
PAN5 YHR063C 2-dehydropantoate 2-reductase physical 1 1 1 Affinity Capture-MS
SCD6 YPR129W Repressor of translation initiation physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SNA4 YDL123W Protein of unknown function physical 1 1 1 Affinity Capture-MS
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes physical 1 1 1 Affinity Capture-MS
COX11 YPL132W Protein required for delivery of copper to Cox1p physical 1 1 1 Affinity Capture-MS
CYC2 YOR037W Mitochondrial peripheral inner membrane protein physical 1 1 1 Affinity Capture-MS
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
ERG4 YGL012W C-24(28) sterol reductase physical 1 1 1 Affinity Capture-MS
MUP1 YGR055W High affinity methionine permease physical 1 1 1 Affinity Capture-MS
PIS1 YPR113W Phosphatidylinositol synthase physical 1 1 1 Affinity Capture-MS
BAP2 YBR068C High-affinity leucine permease physical 1 1 1 Affinity Capture-MS
SHR3 YDL212W Endoplasmic reticulum packaging chaperone physical 1 1 1 Affinity Capture-MS
DPP1 YDR284C Diacylglycerol pyrophosphate (DGPP) phosphatase physical 1 1 1 Affinity Capture-MS
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p physical 1 1 1 Affinity Capture-MS
ERS1 YCR075C Protein involved in cystine transport physical 1 1 1 Affinity Capture-MS
LYP1 YNL268W Lysine permease physical 1 1 1 Affinity Capture-MS
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Positive Genetic
COS10 YNR075W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 Affinity Capture-MS
ELO1 YJL196C Elongase I, medium-chain acyl elongase physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane physical 1 1 1 Affinity Capture-MS
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Proximity Label-MS
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex physical 1 1 1 Affinity Capture-MS
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase physical 1 1 1 Affinity Capture-MS
KEI1 YDR367W Component of inositol phosphorylceramide (IPC) synthase physical 1 1 1 Affinity Capture-MS
IRC15 YPL017C Microtubule associated protein physical 1 1 1 Affinity Capture-MS
GAS2 YLR343W 1,3-beta-glucanosyltransferase physical 1 1 1 Affinity Capture-MS
PIC2 YER053C Mitochondrial copper and phosphate carrier physical 1 1 1 Affinity Capture-MS
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex physical 1 1 1 Affinity Capture-MS
DGK1 YOR311C Diacylglycerol kinase physical 1 1 1 Affinity Capture-MS
PER1 YCR044C Protein of the endoplasmic reticulum physical 1 1 1 Affinity Capture-MS
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter physical 1 1 1 Affinity Capture-MS
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 Affinity Capture-MS
NAT2 YGR147C Protein of unknown function physical 1 1 1 Affinity Capture-MS
MSH1 YHR120W DNA-binding protein of the mitochondria physical 1 1 1 Affinity Capture-MS
MNT3 YIL014W Alpha-1,3-mannosyltransferase physical 1 1 1 Affinity Capture-MS
SFC1 YJR095W Mitochondrial succinate-fumarate transporter physical 1 1 1 Affinity Capture-MS
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS