Standard name Systematic name Name description Description
CDC60 YPL160W Cytosolic leucyl tRNA synthetase Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA; human homolog LARS can complement yeast temperature-sensitive mutant at restrictive temperature
Visualize the interactome of CDC60
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.993 0.98 0.972

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 158000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CDC60 1 0 0 2 0

Enzyme information

Catalyzed reactions in Yeast8
r_0701 (leucyl-tRNA synthetase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 4 2 4 Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TAN1 YGL232W Putative tRNA acetyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 3 3 1 Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
ATG7 YHR171W Autophagy-related protein and dual specificity member of the E1 family genetic 2 1 2 Negative Genetic, Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 2 1 2 Negative Genetic, Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 2 Negative Genetic, Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 2 1 2 Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 2 1 2 Negative Genetic, Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 2 1 2 Negative Genetic, Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 1 2 Positive Genetic, Positive Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 2 1 2 Positive Genetic, Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 2 1 2 Positive Genetic, Positive Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 2 Positive Genetic, Positive Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 2 1 2 Positive Genetic, Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 2 Positive Genetic, Positive Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 2 1 2 Positive Genetic, Positive Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 2 1 2 Positive Genetic, Positive Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 2 1 2 Positive Genetic, Positive Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 2 Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 1 2 Negative Genetic, Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 2 1 2 Negative Genetic, Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 2 1 2 Negative Genetic, Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 2 1 2 Negative Genetic, Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 2 1 2 Negative Genetic, Negative Genetic
GSP1 YLR293C Ran GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 2 1 2 Negative Genetic, Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 2 1 2 Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 2 1 2 Negative Genetic, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 1 2 Negative Genetic, Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 2 1 2 Negative Genetic, Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 1 2 Negative Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 2 1 2 Negative Genetic, Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 2 1 2 Negative Genetic, Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 2 1 2 Negative Genetic, Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 2 1 2 Negative Genetic, Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 2 1 2 Negative Genetic, Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 2 1 1 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 2 1 1 Negative Genetic, Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) physical 1 1 1 Affinity Capture-MS
GDH3 YAL062W NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
DNF1 YER166W Aminophospholipid translocase (flippase) physical 1 1 1 Affinity Capture-MS
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 PCA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase genetic 1 1 1 Negative Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
SRY1 YKL218C 3-hydroxyaspartate dehydratase genetic 1 1 1 Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Positive Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Positive Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Positive Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Positive Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Positive Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Positive Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 1 1 1 Positive Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Positive Genetic
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins genetic 1 1 1 Positive Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
ERD2 YBL040C HDEL receptor genetic 1 1 1 Negative Genetic
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
YBR016W YBR016W Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p genetic 1 1 1 Negative Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
DOG1 YHR044C 2-deoxyglucose-6-phosphate phosphatase genetic 1 1 1 Negative Genetic
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator genetic 1 1 1 Negative Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Negative Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
TIS11 YLR136C mRNA-binding protein expressed during iron starvation genetic 1 1 1 Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Positive Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Positive Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Positive Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Positive Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Positive Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Positive Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Positive Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Positive Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Positive Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Positive Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Positive Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Positive Genetic
YKR011C YKR011C Protein of unknown function genetic 1 1 1 Positive Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Positive Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Positive Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Positive Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Positive Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Positive Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Positive Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Positive Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Positive Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MIX14 YDR031W Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
YHC3 YJL059W Protein required for the ATP-dependent transport of arginine genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Negative Genetic
FBP1 YLR377C Fructose-1,6-bisphosphatase genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Negative Genetic
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Positive Genetic
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase genetic 1 1 1 Negative Genetic
ATP16 YDL004W Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase genetic 1 1 1 Negative Genetic
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
ASP3-2 YLR157C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
BER1 YLR412W Protein involved in microtubule-related processes genetic 1 1 1 Positive Genetic