Standard name Systematic name Name description Description
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) Peptidyl-prolyl cis-trans isomerase (PPIase); binds to FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function; associates with promoters of ribosomal protein genes; acts as chaperone to prevent protein aggregation; N-terminally propionylated in vivo; mutation is functionally complemented by human FKBP1A
Visualize the interactome of FPR1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 0.989 0.957

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 43300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FPR1 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) physical 6 4 5 Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, PCA
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 5 3 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
FAP1 YNL023C Protein that binds to Fpr1p physical 4 3 3 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Co-localization
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 3 2 3 Negative Genetic, Phenotypic Enhancement, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 3 2 3 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 3 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 3 2 3 Phenotypic Suppression, Positive Genetic, Positive Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 2 2 Proximity Label-MS, Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 2 2 Phenotypic Suppression, Positive Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 2 2 2 Phenotypic Suppression, Positive Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 2 2 2 Phenotypic Suppression, Positive Genetic
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II physical 2 2 2 Affinity Capture-MS, Two-hybrid
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 2 2 2 Phenotypic Suppression, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 2 2 2 Phenotypic Suppression, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 2 Positive Genetic, Positive Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 2 1 2 Negative Genetic, Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 2 1 2 Positive Genetic, Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 2 Positive Genetic, Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 2 1 2 Positive Genetic, Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 2 1 2 Negative Genetic, Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ACH1 YBL015W Protein with CoA transferase activity genetic 2 1 2 Negative Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 2 2 1 Affinity Capture-Western, PCA
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 1 Negative Genetic, Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 2 1 1 Negative Genetic, Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 2 1 1 Negative Genetic, Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
YDL086W YDL086W Putative carboxymethylenebutenolidase genetic 2 1 1 Negative Genetic, Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 2 1 1 Negative Genetic, Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 2 1 1 Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 1 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 1 1 1 Positive Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
APL3 YBL037W Alpha-adaptin genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export physical 1 1 1 Affinity Capture-Western
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
FAP1 YNL023C Protein that binds to Fpr1p genetic 1 1 1 Dosage Rescue
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH physical 1 1 1 Affinity Capture-MS
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 1 1 1 Affinity Capture-MS
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Synthetic Rescue
YDR341C YDR341C Arginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
URA1 YKL216W Dihydroorotate dehydrogenase physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
THS1 YIL078W Threonyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity physical 1 1 1 Affinity Capture-MS
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 Affinity Capture-MS
SEN15 YMR059W Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
GDI1 YER136W GDP dissociation inhibitor physical 1 1 1 Affinity Capture-MS
HSH49 YOR319W U2-snRNP associated splicing factor physical 1 1 1 Affinity Capture-MS
KRS1 YDR037W Lysyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
PDL32 YMR087W Putative ADP-ribose-1''-monophosphatase physical 1 1 1 Two-hybrid
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-Western
NGR1 YBR212W RNA binding protein that negatively regulates growth rate physical 1 1 1 Affinity Capture-MS
YIL161W YIL161W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
MRP2 YPR166C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Biochemical Activity
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Affinity Capture-Western
LST8 YNL006W Protein required for the transport of Gap1p physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Rescue
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Two-hybrid
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) physical 1 1 1 Two-hybrid
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Dosage Rescue
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Synthetic Rescue
NOP13 YNL175C Nucleolar protein found in preribosomal complexes genetic 1 1 1 Negative Genetic
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 1 1 1 Negative Genetic
GAL3 YDR009W Transcriptional regulator genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
NMD5 YJR132W Karyopherin genetic 1 1 1 Positive Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
LTV1 YKL143W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Positive Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Positive Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Positive Genetic
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Positive Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
SDH7 YDR511W Mitochondrial protein involved in assembly of succinate dehydrogenase genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Negative Genetic
YPR015C YPR015C Putative zinc finger transcription factor genetic 1 1 1 Negative Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Lethality
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Phenotypic Suppression
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Synthetic Rescue
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Positive Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Positive Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Positive Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPL21A YBR191W Ribosomal 60S subunit protein L21A genetic 1 1 1 Negative Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
YDL129W YDL129W Protein of unknown function genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Negative Genetic
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Negative Genetic
RKM3 YBR030W Ribosomal lysine methyltransferase genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
RTN1 YDR233C Reticulon protein genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
PIB1 YDR313C RING-type ubiquitin ligase of the endosomal and vacuolar membranes genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Negative Genetic
YGR237C YGR237C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAY1 YGR263C Sterol deacetylase genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
YIL108W YIL108W Putative metalloendopeptidase genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
JLP1 YLL057C Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
RGM1 YMR182C Putative zinc finger DNA binding transcription factor genetic 1 1 1 Negative Genetic
MLO1 YMR252C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
YOR019W YOR019W Protein of unknown function genetic 1 1 1 Negative Genetic
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
RPL7B YPL198W Ribosomal 60S subunit protein L7B genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 1 1 1 Negative Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Positive Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Positive Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Dosage Lethality
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Phenotypic Enhancement
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Biochemical Activity
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Two-hybrid
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CUE5 YOR042W Ubiquitin-binding protein physical 1 1 1 Affinity Capture-Western
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Negative Genetic
CGI121 YML036W Component of the EKC/KEOPS complex genetic 1 1 1 Positive Genetic
FMS1 YMR020W Polyamine oxidase genetic 1 1 1 Negative Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Negative Genetic
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
DCR2 YLR361C Protein phosphatase genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Negative Genetic
DIA3 YDL024C Protein of unknown function genetic 1 1 1 Negative Genetic
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 1 1 1 Negative Genetic