| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
4 |
3 |
4 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
1 |
4 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Rescue, Negative Genetic |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
| SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
| CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NAM2 |
YLR382C |
Mitochondrial leucyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPK9 |
YOR291W |
Vacuolar protein with a possible role in sequestering heavy metals |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Co-fractionation |
| HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOL1 |
YNR055C |
Putative transporter in the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| HER1 |
YOR227W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDH2 |
YAL061W |
Putative medium-chain alcohol dehydrogenase with similarity to BDH1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSS1 |
YMR287C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DUG2 |
YBR281C |
Component of glutamine amidotransferase (GATase II) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAC1 |
YOR178C |
Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD7 |
YOR299W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDT1 |
YBR187W |
Calcium and manganese transporter with higher affinity for Ca2+ |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CPR3 |
YML078W |
Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAR3 |
YMR052W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNT1 |
YOR320C |
N-acetylglucosaminyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSE1 |
YER124C |
Daughter cell-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CST26 |
YBR042C |
Acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUN26 |
YAL022C |
High affinity, broad selectivity, nucleoside/nucleobase transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AEP3 |
YPL005W |
Peripheral mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRS1 |
YNL247W |
Cysteinyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DDP1 |
YOR163W |
Diadenosine and diphosphoinositol polyphosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUG1 |
YML058W-A |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSF1 |
YOR271C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MRPS5 |
YBR251W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Co-fractionation |
| NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUS5 |
YLR165C |
Pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLS1 |
YLR139C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RLI1 |
YDR091C |
Essential Fe-S protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP8 |
YBL018C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSM1 |
YGR171C |
Mitochondrial methionyl-tRNA synthetase (MetRS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NMD5 |
YJR132W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSK1 |
YNL073W |
Mitochondrial lysine-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM30 |
YLR368W |
F-box component of an SCF ubiquitin protein ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INA17 |
YPL099C |
F1F0 ATPase synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LDH1 |
YBR204C |
Serine hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR012C |
YLR012C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRC15 |
YPL017C |
Microtubule associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPL034W |
YPL034W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPL247C |
YPL247C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTH2 |
YBL057C |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEF1 |
YBL066C |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS22 |
YBL091C-A |
Protein involved in regulation of phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCO2 |
YBR024W |
Protein anchored to mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR090C |
YBR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSW1 |
YBR148W |
Protein required for normal prospore membrane formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBS1 |
YBR150C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTC20 |
YBR188C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCH1 |
YDL054C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX8 |
YDR336W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAU5 |
YFL020C |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFR018C |
YFR018C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INA22 |
YIR024C |
F1F0 ATP synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR146W |
YJR146W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET14 |
YKL001C |
Adenylylsulfate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KTR2 |
YKR061W |
Mannosyltransferase involved in N-linked protein glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR053C |
YLR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCL2 |
YLR104W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL034W |
YNL034W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR061C |
YNR061C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUL3 |
YNR062C |
Putative pulcherrimin transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR065C |
YNR065C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR071C |
YNR071C |
Putative aldose 1-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN2 |
YOR104W |
Exomer-dependent cargo protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWT1 |
YOR166C |
RNA endoribonuclease involved in perinuclear mRNP quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAX1 |
YOR301W |
Protein involved in establishing bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHR1 |
YOR386W |
DNA photolyase involved in photoreactivation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM44 |
YPL030W |
tRNA(Ser) Um(44) 2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL071C |
YPL071C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP16 |
YPL072W |
Deubiquitinating enzyme anchored to the outer mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDC1 |
YPL087W |
Alkaline dihydroceramidase, involved in sphingolipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PXA1 |
YPL147W |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET20 |
YPL159C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGC1 |
YPL206C |
Phosphatidylglycerol phospholipase C |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRS4 |
YBL068W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRA1 |
YBR140C |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIM1 |
YMR152W |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR096W |
YJR096W |
Xylose and arabinose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSH1 |
YHR120W |
DNA-binding protein of the mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO5 |
YBR093C |
Repressible acid phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMC2 |
YBR104W |
Putative mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| COX8 |
YLR395C |
Subunit VIII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSD1 |
YGL196W |
D-serine dehydratase (aka D-serine ammonia-lyase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM33 |
YML087C |
Protein of unknown function, highly conserved across species |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM23 |
YPL021W |
Non-essential protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Negative Genetic |
