Standard name Systematic name Name description Description
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex; uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair
Visualize the interactome of HAT1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HAT1 6 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 12 5 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Co-crystal Structure, Reconstituted Complex
HHF1 YBR009C Histone H4 physical 10 4 9 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity, Biochemical Activity
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 10 3 7 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
HHF2 YNL030W Histone H4 physical 6 4 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 5 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ORC3 YLL004W Subunit of the origin recognition complex (ORC) physical 5 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 4 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
HHT2 YNL031C Histone H3 physical 4 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 4 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 4 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ORC6 YHR118C Subunit of the origin recognition complex (ORC) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ORC4 YPR162C Subunit of the origin recognition complex (ORC) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
ASF1 YJL115W Nucleosome assembly factor physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
HHT1 YBR010W Histone H3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HHT1 YBR010W Histone H3 genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PGS1 YCL004W Phosphatidylglycerolphosphate synthase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSQ1 YLR369W Mitochondrial hsp70-type molecular chaperone genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
YVH1 YIR026C Dual specificity protein phosphatase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GEP5 YLR091W Protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Phenotypic Enhancement
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Synthetic Growth Defect
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex genetic 1 1 1 Phenotypic Enhancement
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 1 1 1 Affinity Capture-MS
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Synthetic Growth Defect
HHT2 YNL031C Histone H3 genetic 1 1 1 Phenotypic Enhancement
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Synthetic Growth Defect
YML131W YML131W Protein of unknown function physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes physical 1 1 1 Affinity Capture-MS
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Affinity Capture-MS
YJR154W YJR154W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
RPL37A YLR185W Ribosomal 60S subunit protein L37A physical 1 1 1 Affinity Capture-MS
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-Western
KAP123 YER110C Karyopherin beta physical 1 1 1 Reconstituted Complex
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Positive Genetic
LSO2 YGR169C-A Ribosome-associated protein genetic 1 1 1 Positive Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
NSA1 YGL111W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family genetic 1 1 1 Negative Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 1 1 1 Negative Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Negative Genetic
VBA4 YDR119W Protein of unknown function genetic 1 1 1 Negative Genetic
YER039C-A YER039C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
MIL1 YFL034W Predicted lipase genetic 1 1 1 Negative Genetic
YFR006W YFR006W Putative X-Pro aminopeptidase genetic 1 1 1 Negative Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Negative Genetic
YGR016W YGR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR153W YGR153W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Negative Genetic
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Negative Genetic
YJR056C YJR056C Protein of unknown function genetic 1 1 1 Negative Genetic
YKR005C YKR005C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPO75 YLL005C Meiosis-specific protein of unknown function genetic 1 1 1 Negative Genetic
YLR159W YLR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR456W YLR456W Protein of unknown function genetic 1 1 1 Negative Genetic
MIN4 YML007C-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs genetic 1 1 1 Negative Genetic
ISF1 YMR081C Serine-rich, hydrophilic protein genetic 1 1 1 Negative Genetic
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Negative Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Negative Genetic
TMA16 YOR252W Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
PYK2 YOR347C Pyruvate kinase genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Positive Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RGM1 YMR182C Putative zinc finger DNA binding transcription factor genetic 1 1 1 Positive Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Positive Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Co-fractionation
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Synthetic Growth Defect
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 Affinity Capture-MS
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Positive Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
ELA1 YNL230C Elongin A physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
BAP3 YDR046C Amino acid permease genetic 1 1 1 Negative Genetic
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases genetic 1 1 1 Negative Genetic
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 1 1 1 Affinity Capture-MS
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Positive Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Positive Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin genetic 1 1 1 Negative Genetic