Standard name Systematic name Name description Description
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching
Visualize the interactome of CKA2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.788 0.741 0.723
Vac/Vac Memb 0.159 0.241 0.230
Cytoplasm NaN 0.093 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 4540

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CKA2 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 16 5 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 16 4 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Two-hybrid, Two-hybrid
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 15 4 12 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 12 6 11 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 8 1 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 8 1 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 7 2 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 5 2 5 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 5 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 5 3 2 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein physical 4 3 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
SEC22 YLR268W R-SNARE protein genetic 4 2 3 Positive Genetic, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SPT2 YER161C Protein involved in negative regulation of transcription physical 4 3 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain physical 4 2 2 Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Biochemical Activity
EOS1 YNL080C Protein involved in N-glycosylation genetic 4 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HHT2 YNL031C Histone H3 physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 3 2 3 Affinity Capture-MS, Biochemical Activity, Biochemical Activity
UTP22 YGR090W Component of the small-subunit processome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CAB3 YKL088W Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MIF2 YKL089W Centromeric CDEIII region binding protein physical 3 3 2 Two-hybrid, Affinity Capture-MS, Biochemical Activity
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 3 3 2 Biochemical Activity, Affinity Capture-Western, Affinity Capture-MS
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 3 3 2 Affinity Capture-MS, Two-hybrid, Biochemical Activity
SVF1 YDR346C Protein with a potential role in cell survival pathways physical 3 2 2 Biochemical Activity, Affinity Capture-Western, Biochemical Activity
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Co-purification
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 3 2 2 Positive Genetic, Phenotypic Suppression, Phenotypic Suppression
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 3 3 1 Dosage Rescue, Dosage Growth Defect, Synthetic Lethality
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 3 3 1 Dosage Rescue, Dosage Growth Defect, Synthetic Lethality
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 Affinity Capture-MS, Two-hybrid
LIF1 YGL090W Component of the DNA ligase IV complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
MIH1 YMR036C Protein tyrosine phosphatase physical 2 2 2 Biochemical Activity, Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
HHF2 YNL030W Histone H4 physical 2 2 2 Affinity Capture-MS, Biochemical Activity
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-MS, Biochemical Activity
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 2 2 2 PCA, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Dosage Rescue, Synthetic Growth Defect
TUB4 YLR212C Gamma-tubulin genetic 2 2 2 Dosage Rescue, Synthetic Rescue
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 2 2 2 Synthetic Lethality, Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 2 2 Dosage Lethality, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 2 2 Dosage Rescue, Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
CDC73 YLR418C Component of the Paf1p complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSF1 YGL073W Trimeric heat shock transcription factor physical 2 1 2 Biochemical Activity, Biochemical Activity
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 1 2 Positive Genetic, Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 2 Positive Genetic, Positive Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 2 Positive Genetic, Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 2 1 2 Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 1 2 Negative Genetic, Negative Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Positive Genetic, Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
LAC1 YKL008C Ceramide synthase component genetic 2 1 2 Negative Genetic, Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 2 1 2 Positive Genetic, Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 2 Negative Genetic, Negative Genetic
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 2 2 1 Affinity Capture-Western, Biochemical Activity
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 2 2 1 Affinity Capture-Western, Biochemical Activity
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III physical 2 2 1 Biochemical Activity, Affinity Capture-Western
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription physical 2 2 1 Affinity Capture-Western, Biochemical Activity
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
CHC1 YGL206C Clathrin heavy chain physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GET2 YER083C Subunit of the GET complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 co-immunoprecipitation evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Dosage Lethality
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Phenotypic Suppression
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Positive Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Phenotypic Suppression
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Affinity Capture-MS
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies physical 1 1 1 Affinity Capture-MS
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-Western
CMD1 YBR109C Calmodulin genetic 1 1 1 Dosage Rescue
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 Two-hybrid
TAF13 YML098W TFIID subunit (19 kDa) physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Biochemical Activity
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Biochemical Activity
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Biochemical Activity
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 1 1 1 Biochemical Activity
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Positive Genetic
RSM18 YER050C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) physical 1 1 1 Affinity Capture-MS
YLR407W YLR407W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Affinity Capture-MS
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-MS
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Affinity Capture-MS
OPI1 YHL020C Transcriptional regulator of a variety of genes physical 1 1 1 Biochemical Activity
NRG1 YDR043C Transcriptional repressor physical 1 1 1 Biochemical Activity
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Biochemical Activity
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes physical 1 1 1 Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RRP36 YOR287C Component of 90S preribosomes physical 1 1 1 Affinity Capture-MS
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
PXR1 YGR280C Essential protein involved in rRNA and snoRNA maturation physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 1 1 1 Affinity Capture-MS
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p physical 1 1 1 Affinity Capture-MS
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
MKS1 YNL076W Pleiotropic negative transcriptional regulator physical 1 1 1 Affinity Capture-MS
PKH1 YDR490C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
PSR2 YLR019W Putative plasma membrane phosphatase physical 1 1 1 Affinity Capture-MS
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Affinity Capture-MS
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter physical 1 1 1 Affinity Capture-Western
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RPP2B YDR382W Ribosomal protein P2 beta physical 1 1 1 Biochemical Activity
TOM20 YGR082W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Biochemical Activity
MIM1 YOL026C Mitochondrial protein required for outer membrane protein import physical 1 1 1 Biochemical Activity
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Biochemical Activity
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Phenotypic Suppression
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
TIF5 YPR041W Translation initiation factor eIF5 physical 1 1 1 Biochemical Activity
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
CRF1 YDR223W Transcriptional corepressor physical 1 1 1 Biochemical Activity
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
MSN2 YMR037C Stress-responsive transcriptional activator physical 1 1 1 Biochemical Activity
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
MSN4 YKL062W Stress-responsive transcriptional activator physical 1 1 1 Biochemical Activity
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 1 1 1 Two-hybrid
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Two-hybrid
NOP19 YGR251W Ribosome biogenesis factor physical 1 1 1 Two-hybrid
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
EFB1 YAL003W Translation elongation factor 1 beta genetic 1 1 1 Negative Genetic
TAD2 YJL035C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
SLS1 YLR139C Mitochondrial membrane protein genetic 1 1 1 Positive Genetic
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Positive Genetic
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Positive Genetic
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Positive Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Positive Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Positive Genetic
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein genetic 1 1 1 Positive Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Positive Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Positive Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 1 1 1 Positive Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Positive Genetic
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
FIR1 YER032W Protein involved in 3' mRNA processing genetic 1 1 1 Positive Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Positive Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Positive Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Positive Genetic
NPP1 YCR026C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Positive Genetic
RHB1 YCR027C Putative Rheb-related GTPase genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Positive Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Positive Genetic
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Positive Genetic
YMR1 YJR110W Phosphatidylinositol 3-phosphate (PI3P) phosphatase genetic 1 1 1 Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Positive Genetic
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
YEA6 YEL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Positive Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Positive Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Suppression
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Positive Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Dosage Rescue
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Dosage Rescue
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Rescue
NDJ1 YOL104C Protein that regulates meiotic SPB cohesion and telomere clustering genetic 1 1 1 Dosage Growth Defect
SBE2 YDR351W Protein required for bud growth genetic 1 1 1 Dosage Growth Defect
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Growth Defect
SBE22 YHR103W Protein involved in bud growth genetic 1 1 1 Dosage Growth Defect
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Dosage Growth Defect
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Dosage Growth Defect
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Negative Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
PPT1 YGR123C Protein serine/threonine phosphatase genetic 1 1 1 Synthetic Growth Defect
LAG1 YHL003C Ceramide synthase component genetic 1 1 1 Dosage Growth Defect
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Positive Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Positive Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Positive Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Positive Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
KRE29 YER038C Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
FAF1 YIL019W Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
PZF1 YPR186C Transcription factor IIIA (TFIIIA) genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
COX9 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
PAU10 YDR542W Protein of unknown function genetic 1 1 1 Negative Genetic
PET117 YER058W Assembly factor that couples heme a synthesis to complex IV assembly genetic 1 1 1 Negative Genetic
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
COX16 YJL003W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Dosage Lethality
YRM1 YOR172W Zinc finger transcription factor involved in multidrug resistance genetic 1 1 1 Dosage Lethality
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Dosage Lethality
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Dosage Lethality
MATALPHA2 YCR039C Homeobox-domain protein genetic 1 1 1 Dosage Lethality
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth genetic 1 1 1 Dosage Lethality
DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts genetic 1 1 1 Dosage Lethality
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Dosage Lethality
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
MRPS12 YNR036C Mitochondrial protein genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Phenotypic Suppression
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Positive Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
FAA4 YMR246W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Positive Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Positive Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Positive Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Dosage Rescue
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor physical 1 1 1 Affinity Capture-MS
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Positive Genetic
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone physical 1 1 1 Biochemical Activity
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Biochemical Activity
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CBF2 YGR140W Essential kinetochore protein physical 1 1 1 Biochemical Activity
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity physical 1 1 1 Reconstituted Complex
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Positive Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
AFT2 YPL202C Iron-regulated transcriptional activator genetic 1 1 1 Dosage Lethality
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic