Standard name Systematic name Name description Description
NET1 YJL076W Core subunit of the RENT complex Core subunit of the RENT complex; involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure; NET1 has a paralog, TOF2, that arose from the whole genome duplication
Visualize the interactome of NET1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.950 0.700 0.851
Nucleus 0.069 0.075 0.059
SpindlePole 0.098 NaN 0.311
Cytoplasm NaN 0.250 NaN
Budneck NaN NaN 0.086

GFP localization & abundance

GFP localization GFP abundance
nucleolus 1590

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NET1 0 3 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 29 5 19 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 24 5 17 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 7 2 6 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 7 4 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 5 2 5 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 4 3 4 Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Proximity Label-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 4 2 4 PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 4 2 4 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 4 4 2 Two-hybrid, Biochemical Activity, Affinity Capture-Western, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 3 2 3 Dosage Rescue, Synthetic Rescue, Dosage Rescue
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 3 2 3 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 3 1 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 3 2 2 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
RPA43 YOR340C RNA polymerase I subunit A43 physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
NUR1 YDL089W Protein involved in regulation of mitotic exit physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SPO12 YHR152W Nucleolar protein of unknown function genetic 2 2 2 Synthetic Rescue, Synthetic Lethality
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 2 2 2 Biochemical Activity, Proximity Label-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
PRP43 YGL120C RNA helicase in the DEAH-box family physical 2 2 1 Two-hybrid, Affinity Capture-Western
NSI1 YDR026C RNA polymerase I termination factor physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
MOB1 YIL106W Component of the mitotic exit network physical 2 2 1 Affinity Capture-Western, Proximity Label-MS
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency
RPA43 YOR340C RNA polymerase I subunit A43 genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 1 1 1 protein kinase assay evidence
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RGM1 YMR182C Putative zinc finger DNA binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
INO2 YDR123C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
DAL82 YNL314W Positive regulator of allophanate inducible genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MSS11 YMR164C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RAD53 YPL153C DNA damage response kinase regulation 1 1 1 protein kinase assay evidence
CUP2 YGL166W Copper-binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
MYO1 YHR023W Type II myosin heavy chain genetic 1 1 1 Synthetic Lethality
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Phenotypic Suppression
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Co-localization
UTP9 YHR196W Nucleolar protein physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Affinity Capture-MS
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 PCA
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 PCA
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-Western
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Affinity Capture-MS
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway physical 1 1 1 Affinity Capture-MS
PSR2 YLR019W Putative plasma membrane phosphatase physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I genetic 1 1 1 Dosage Rescue
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Synthetic Lethality
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase physical 1 1 1 Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase physical 1 1 1 Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Affinity Capture-MS
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 1 1 1 Synthetic Rescue
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Phenotypic Suppression
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Biochemical Activity
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p physical 1 1 1 Affinity Capture-MS
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Biochemical Activity
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-MS
DCS2 YOR173W m(7)GpppX pyrophosphatase regulator physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Suppression
MET14 YKL001C Adenylylsulfate kinase physical 1 1 1 Affinity Capture-MS
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Phenotypic Suppression
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS