MSN1 |
YOL116W |
Transcriptional activator |
genetic |
5 |
2 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Suppression |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
regulation |
4 |
4 |
4 |
beta-galactosidase reporter gene assay evidence, DNA to cDNA expression microarray evidence, northern blot evidence, nucleic acid binding evidence |
FLO8 |
YER109C |
Transcription factor |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Phenotypic Suppression |
FLO8 |
YER109C |
Transcription factor |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
SUT2 |
YPR009W |
Zn2Cys6 family transcription factor |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPQ2 |
YDR352W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
AFB1 |
YLR040C |
MATalpha-specific a-factor blocker |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CQD2 |
YLR253W |
Mitochondrial protein involved in lipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GTS1 |
YGL181W |
Protein involved in Arf3p regulation and in transcription regulation |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
2 |
1 |
1 |
Dosage Rescue, Dosage Rescue |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GRE3 |
YHR104W |
Aldose reductase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GSC2 |
YGR032W |
Catalytic subunit of 1,3-beta-glucan synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TIR3 |
YIL011W |
Cell wall mannoprotein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NET1 |
YJL076W |
Core subunit of the RENT complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
REE1 |
YJL217W |
Cytoplasmic protein involved in the regulation of enolase (ENO1) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
regulation |
1 |
1 |
1 |
reporter gene assay evidence |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
regulation |
1 |
1 |
1 |
beta-galactosidase reporter gene assay evidence |
CUP1-1 |
YHR053C |
Metallothionein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CUP1-2 |
YHR055C |
Metallothionein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ECM34 |
YHL043W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CMR3 |
YPR013C |
Putative zinc finger protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MSS11 |
YMR164C |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BTN2 |
YGR142W |
v-SNARE binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YLR053C |
YLR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YEF1 |
YEL041W |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPH1 |
YLR313C |
Protein involved in shmoo formation and bipolar bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
LAG2 |
YOL025W |
Protein that negatively regulates the SCF E3-ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABZ2 |
YMR289W |
Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MFG1 |
YDL233W |
Regulator of filamentous growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP78 |
YDR258C |
Oligomeric mitochondrial matrix chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
IZH2 |
YOL002C |
Plasma membrane receptor for plant antifungal osmotin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FLO10 |
YKR102W |
Member of the FLO family of cell wall flocculation proteins |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |