Standard name Systematic name Name description Description
MEP1 YGR121C Ammonium permease Ammonium permease; belongs to Mep-Amt-Rh family of well-conserved ammonium (NH4+) transporters that includes the human Rh factors; expression is under the nitrogen catabolite repression regulation; activity regulated by TORC1 effectors, Npr1p and Par32p; human homolog RHCG complements yeast null mutant; mutations in human homolog RHCG implicated in metabolic acidosis; MEP1 has a paralog, MEP3, that arose from the whole genome duplication
Visualize the interactome of MEP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.895 0.925 0.905
Cort. Patches 0.268 0.261 0.189
Mito 0.089 NaN NaN
Cytoplasm NaN NaN 0.050

GFP localization & abundance

GFP localization GFP abundance
cell periphery technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MEP1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1115 (ammonia transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MEP3 YPR138C Ammonium permease of high capacity and low affinity genetic 8 3 6 Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue, Dosage Rescue
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth genetic 7 4 6 Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 2 Negative Genetic, Negative Genetic
GTT1 YIR038C ER associated glutathione S-transferase physical 2 1 2 Two-hybrid, Two-hybrid
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 1 2 Negative Genetic, Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 2 1 2 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Dosage Rescue
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Dosage Rescue
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Positive Genetic
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 PCA
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
FUI1 YBL042C High affinity uridine permease, localizes to the plasma membrane genetic 1 1 1 Negative Genetic
ATG34 YOL083W Receptor protein involved in selective autophagy during starvation genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Negative Genetic
FUS2 YMR232W Cell fusion regulator genetic 1 1 1 Negative Genetic
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Dosage Rescue
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Dosage Rescue
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Negative Genetic
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway genetic 1 1 1 Negative Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
IRC7 YFR055W Cysteine desulphydrase, enables growth on cysteine as nitrogen source genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
DTR1 YBR180W Putative dityrosine transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
ERS1 YCR075C Protein involved in cystine transport genetic 1 1 1 Negative Genetic
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
MEP3 YPR138C Ammonium permease of high capacity and low affinity physical 1 1 1 PCA
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 PCA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
PMT3 YOR321W Protein O-mannosyltransferase physical 1 1 1 PCA
PAR32 YDL173W Low complexity protein physical 1 1 1 Affinity Capture-Western
PAR32 YDL173W Low complexity protein genetic 1 1 1 Phenotypic Suppression
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Dosage Rescue
MSN5 YDR335W Karyopherin genetic 1 1 1 Dosage Rescue
MSS11 YMR164C Transcription factor genetic 1 1 1 Dosage Rescue
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth genetic 1 1 1 Dosage Rescue
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Dosage Rescue
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Dosage Rescue
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Dosage Rescue
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Dosage Rescue
SSD1 YDR293C Translational repressor genetic 1 1 1 Dosage Rescue
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Dosage Rescue
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Positive Genetic
RRT12 YCR045C Probable subtilisin-family protease genetic 1 1 1 Positive Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YCL049C YCL049C Protein of unknown function genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
PUG1 YER185W Plasma membrane protein involved in protoprophyrin and heme transport genetic 1 1 1 Negative Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAL037W YAL037W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
RFU1 YLR073C Protein that inhibits Doa4p deubiquitinating activity genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
YMR030W-A YMR030W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
NPR1 YNL183C Protein kinase genetic 1 1 1 Dosage Rescue
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
CIS1 YLR346C Protein of unknown function found in mitochondria genetic 1 1 1 Negative Genetic
FSH1 YHR049W Lysophospholipase genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Dosage Rescue