Standard name Systematic name Name description Description
PPX1 YHR201C Exopolyphosphatase Exopolyphosphatase; hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix
Visualize the interactome of PPX1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.988 1.0 0.987

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 3170

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PPX1 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4333 (Polyphosphate phosphohydrolase), r_4403 (Triphosphate phosphohydrolase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Positive Genetic
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
HEL2 YDR266C RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
PIB1 YDR313C RING-type ubiquitin ligase of the endosomal and vacuolar membranes genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
GYP6 YJL044C GTPase-activating protein (GAP) for yeast Rab family member Ypt6p genetic 1 1 1 Negative Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
LUG1 YLR352W Protein of unknown function with similarity to F-box proteins genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase physical 1 1 1 Biochemical Activity
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Negative Genetic
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
LAC1 YKL008C Ceramide synthase component genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CUE2 YKL090W Ubiquitin-binding endonuclease involved in mRNA decay genetic 1 1 1 Negative Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Negative Genetic
AGP2 YBR132C Plasma membrane regulator of polyamine and carnitine transport genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
PBP4 YDL053C Pbp1p binding protein genetic 1 1 1 Negative Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism genetic 1 1 1 Phenotypic Enhancement
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Positive Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Positive Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Positive Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Positive Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Positive Genetic
TAZ1 YPR140W Lyso-phosphatidylcholine acyltransferase genetic 1 1 1 Positive Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
SPR28 YDR218C Sporulation-specific homolog of the CDC3/10/11/12 family of genes genetic 1 1 1 Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
RPL27B YDR471W Ribosomal 60S subunit protein L27B genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Negative Genetic
TCD1 YHR003C tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SUC2 YIL162W Invertase genetic 1 1 1 Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
YKL033W-A YKL033W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RCI50 YKL133C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Negative Genetic
PUS5 YLR165C Pseudouridine synthase genetic 1 1 1 Negative Genetic
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Negative Genetic
PUN1 YLR414C Plasma membrane protein with a role in cell wall integrity genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
YPL150W YPL150W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
YPL162C YPL162C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Positive Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
MBR1 YKL093W Protein involved in mitochondrial functions and stress response genetic 1 1 1 Negative Genetic
FMP46 YKR049C Putative redox protein containing a thioredoxin fold genetic 1 1 1 Negative Genetic
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Negative Genetic
ECM22 YLR228C Sterol regulatory element binding protein genetic 1 1 1 Negative Genetic
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Negative Genetic
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Negative Genetic
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
FMP25 YLR077W Protein required for assembly of respiratory complex III genetic 1 1 1 Negative Genetic
MEP1 YGR121C Ammonium permease genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
NNR2 YKL151C Widely-conserved NADHX dehydratase genetic 1 1 1 Negative Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase genetic 1 1 1 Negative Genetic
DIT1 YDR403W Sporulation-specific enzyme required for spore wall maturation genetic 1 1 1 Negative Genetic
BRE4 YDL231C Zinc finger protein containing five transmembrane domains genetic 1 1 1 Negative Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
KHA1 YJL094C Putative K+/H+ antiporter genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
CCC2 YDR270W Cu(+2)-transporting P-type ATPase genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
AVT7 YIL088C Vacuolar amino acid transporter genetic 1 1 1 Negative Genetic
FLX1 YIL134W Mitochondrial flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
FDC1 YDR539W Ferulic acid decarboxylase genetic 1 1 1 Negative Genetic
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Negative Genetic
ICS3 YJL077C Protein with a role in copper homeostasis genetic 1 1 1 Negative Genetic