Standard name Systematic name Name description Description
CUE2 YKL090W Ubiquitin-binding endonuclease involved in mRNA decay Ubiquitin-binding endonuclease involved in mRNA decay; recruited to stalled ribosomes to promote breakdown of transcript body of nuclear-transcribed mRNA with stalls in translation elongation; cleaves mRNA within A site of colliding ribosome; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
Visualize the interactome of CUE2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CUE2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
UBI4 YLL039C Ubiquitin physical 4 2 3 Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor physical 1 1 1 Two-hybrid
THG1 YGR024C tRNAHis guanylyltransferase physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RRI2 YOL117W Subunit of the COP9 signalosome (CSN) complex physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Positive Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Positive Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
YCL001W-B YCL001W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
MRP10 YDL045W-A Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Phenotypic Suppression
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Phenotypic Enhancement
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Phenotypic Enhancement
YPL199C YPL199C Protein involved in nonstop mRNA decay genetic 1 1 1 Phenotypic Enhancement
CEP3 YMR168C Essential kinetochore protein physical 1 1 1 Two-hybrid
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase genetic 1 1 1 Negative Genetic