Standard name Systematic name Name description Description
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) FG-nucleoporin component of central core of nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport; induces membrane tubulation, which may contribute to nuclear pore assembly; ASM4 has a paralog, NUP53, that arose from the whole genome duplication
Visualize the interactome of ASM4
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nuc Periphery 0.683 0.667 0.780
Nucleolus 0.147 0.077 0.152
Nucleus 0.133 0.146 0.071
Vac/Vac Memb 0.291 0.266 0.142
Mito NaN 0.062 0.090
Endosome NaN NaN 0.081

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 2740

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ASM4 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 9 2 7 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 8 2 6 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 6 4 5 Two-hybrid, PCA, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, PCA
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 6 3 5 Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 6 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 6 2 4 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 3 3 3 Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 3 3 3 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 2 2 Phenotypic Suppression, Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 2 2 Phenotypic Suppression, Positive Genetic
PRP4 YPR178W Splicing factor genetic 2 2 2 Phenotypic Suppression, Positive Genetic
KAP95 YLR347C Karyopherin beta physical 2 1 2 Reconstituted Complex, Reconstituted Complex
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
TBS1 YBR150C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YBR220C YBR220C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 2 1 2 Negative Genetic, Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 2 1 2 Negative Genetic, Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 2 1 2 Negative Genetic, Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
ACH1 YBL015W Protein with CoA transferase activity genetic 2 1 1 Positive Genetic, Positive Genetic
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RPP2B YDR382W Ribosomal protein P2 beta genetic 2 1 1 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 1 Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 1 1 Negative Genetic, Negative Genetic
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Co-purification
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Reconstituted Complex
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 Two-hybrid
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Reconstituted Complex
KAP123 YER110C Karyopherin beta physical 1 1 1 Reconstituted Complex
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein physical 1 1 1 PCA
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Lethality
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
NMD5 YJR132W Karyopherin genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Positive Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
NNT1 YLR285W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Positive Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Positive Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Synthetic Growth Defect
ERD2 YBL040C HDEL receptor genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
YCL001W-B YCL001W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
YJR098C YJR098C Putative protein of unknown function genetic 1 1 1 Negative Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Negative Genetic
YML002W YML002W Putative protein of unknown function genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Dosage Rescue
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Dosage Rescue
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 1 1 1 Positive Genetic
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Synthetic Lethality
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic