| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
18 |
3 |
16 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
physical |
3 |
3 |
2 |
Two-hybrid, Co-localization, Biochemical Activity |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
3 |
2 |
2 |
Biochemical Activity, Reconstituted Complex, Biochemical Activity |
| PLC1 |
YPL268W |
Phospholipase C |
genetic |
3 |
3 |
1 |
Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EMP24 |
YGL200C |
Component of the p24 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAW1 |
YAL027W |
5'- and 3'-flap DNA binding protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| FUN19 |
YAL034C |
Non-essential protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ACH1 |
YBL015W |
Protein with CoA transferase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GID7 |
YCL039W |
Subunit of GID Complex that binds directly to central component Vid30p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MOH1 |
YBL049W |
Protein of unknown function, essential for stationary phase survival |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| YCR007C |
YCR007C |
Putative integral membrane protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPB2 |
YAL056W |
Multistep regulator of cAMP-PKA signaling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SYP1 |
YCR030C |
Negative regulator of WASP-Arp23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LYS21 |
YDL131W |
Homocitrate synthase isozyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GLK1 |
YCL040W |
Glucokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TCM62 |
YBR044C |
Protein involved in assembly of the succinate dehydrogenase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PET18 |
YCR020C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AVT5 |
YBL089W |
Putative transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EFM2 |
YBR271W |
S-adenosylmethionine-dependent methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YBL029W |
YBL029W |
Non-essential protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
2 |
2 |
1 |
Two-hybrid, PCA |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
2 |
1 |
1 |
PCA, PCA |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
| RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TRZ1 |
YKR079C |
tRNA 3'-end processing endonuclease tRNase Z |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GIR2 |
YDR152W |
Highly-acidic RWD domain-containing cytoplasmic protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PUS4 |
YNL292W |
Pseudouridine synthase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHC1 |
YGL206C |
Clathrin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MBP1 |
YDL056W |
Transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP2 |
YBR233W |
RNA binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGS1 |
YNL218W |
Protein with DNA-dependent ATPase and ssDNA annealing activities |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP6 |
YBR055C |
Splicing factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC4 |
YBR125C |
Cytoplasmic type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA12 |
YJR063W |
RNA polymerase I subunit A12.2 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSH2 |
YDL019C |
Member of an oxysterol-binding protein family with seven members |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVT4 |
YNL101W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CRN1 |
YLR429W |
Coronin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MPC54 |
YOR177C |
Component of the meiotic outer plaque |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FDO1 |
YMR144W |
Protein involved in directionality of mating type switching |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIG2 |
YDR480W |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RTN2 |
YDL204W |
Reticulon protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
| LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS1 |
YNL192W |
Chitin synthase I |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ACS1 |
YAL054C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
physical |
1 |
1 |
1 |
Two-hybrid |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCK1 |
YLR422W |
Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN6 |
YBL014C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADP1 |
YCR011C |
Putative ATP-dependent permease of the ABC transporter family |
physical |
1 |
1 |
1 |
Two-hybrid |
| CTL1 |
YMR180C |
RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm |
physical |
1 |
1 |
1 |
Two-hybrid |
| PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPB1 |
YCL054W |
AdoMet-dependent methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
| YER079W |
YER079W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| YDR170W-A |
YDR170W-A |
Retrotransposon TYA Gag gene |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL284C-A |
YNL284C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR038C-A |
YGR038C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML083C |
YML083C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YHR214C-C |
YHR214C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR126W |
YGR126W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YJR056C |
YJR056C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR326W |
YLR326W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL034W |
YNL034W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPR158W-A |
YPR158W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR410W-A |
YLR410W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YDR034C-C |
YDR034C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR027W-A |
YGR027W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YOL103W-A |
YOL103W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMR046C |
YMR046C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPR158C-C |
YPR158C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML037C |
YML037C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPR137C-A |
YPR137C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML045W-A |
YML045W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR257W |
YLR257W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL054W-A |
YNL054W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPL257W-A |
YPL257W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YDR109C |
YDR109C |
D-ribulokinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPL191C |
YPL191C |
K48-specific deubiquitinating (DUB) enzyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YHR131C |
YHR131C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML096W |
YML096W |
Putative protein with similarity to asparagine synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL033W |
YNL033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR016W |
YCR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOR034C-A |
YOR034C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIR021W-A |
YIR021W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR225C |
YLR225C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL180W |
YDL180W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL113C |
YPL113C |
Glyoxylate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZIP2 |
YGL249W |
Meiosis-specific protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUT3 |
YKL015W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAA2 |
YBL010C |
Clathrin adaptor (adaptin) accessory protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG8 |
YBL078C |
Ub-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELO3 |
YLR372W |
Elongase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HOP1 |
YIL072W |
Meiosis-specific protein required for chromosome synapsis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC5 |
YDR166C |
Essential 107kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNL1 |
YIL016W |
Ribosome-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATC1 |
YDR184C |
Nuclear protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Co-fractionation |
| PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARK1 |
YNL020C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPO74 |
YGL170C |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAR32 |
YDL173W |
Low complexity protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INH1 |
YDL181W |
Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DUS3 |
YLR401C |
Dihydrouridine synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NDJ1 |
YOL104C |
Protein that regulates meiotic SPB cohesion and telomere clustering |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CST26 |
YBR042C |
Acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HEH2 |
YDR458C |
Inner nuclear membrane (INM) protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSI1 |
YDR026C |
RNA polymerase I termination factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRE3 |
YHR104W |
Aldose reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VHS2 |
YIL135C |
Regulator of septin dynamics |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AQY3 |
YFL054C |
Putative channel-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM3 |
YOR092W |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CUZ1 |
YNL155W |
Protein with a role in the ubiquitin-proteasome pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CYC7 |
YEL039C |
Cytochrome c isoform 2, expressed under hypoxic conditions |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTH2 |
YBL057C |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTH2 |
YBL057C |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ2 |
YJL162C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GEP5 |
YLR091W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSA3 |
YLR221C |
Protein with a likely role in ribosomal maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| FYV6 |
YNL133C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCW22 |
YDR134C |
Cell wall protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADD37 |
YMR184W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARV1 |
YLR242C |
Cortical ER protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CMR3 |
YPR013C |
Putative zinc finger protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DUS1 |
YML080W |
Dihydrouridine synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NVJ2 |
YPR091C |
Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MLF3 |
YNL074C |
Serine-rich protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RCM1 |
YNL022C |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAU22 |
YPL282C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDG1 |
YNL173C |
Plasma membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SET5 |
YHR207C |
Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSK1 |
YNL073W |
Mitochondrial lysine-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STP3 |
YLR375W |
Zinc-finger protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UTP25 |
YIL091C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRP1 |
YDR007W |
Phosphoribosylanthranilate isomerase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VCX1 |
YDL128W |
Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SMF1 |
YOL122C |
Divalent metal ion transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YBR225W |
YBR225W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TRI1 |
YMR233W |
Non-essential sumoylated protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YBL086C |
YBL086C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YBR285W |
YBR285W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
physical |
1 |
1 |
1 |
Biochemical Activity |
| THO1 |
YER063W |
Conserved nuclear RNA-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STE3 |
YKL178C |
Receptor for a factor pheromone |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP9 |
YER098W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SGE1 |
YPR198W |
Plasma membrane multidrug transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM27 |
YGR215W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPS18 |
YNL204C |
Protein of unknown function, contains a putative zinc-binding domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBR053C |
YBR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX34 |
YCL056C |
Protein that regulates peroxisome populations |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRY1 |
YKL218C |
3-hydroxyaspartate dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLC3 |
YGL139W |
Putative FAD transporter, similar to Flc1p and Flc2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AFG1 |
YEL052W |
Protein that may act as a chaperone for cytochrome c oxidase subunits |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| LPX1 |
YOR084W |
Peroxisomal matrix-localized lipase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM7 |
YDL039C |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX35 |
YGR168C |
Regulator of peroxisome abundance |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NGL1 |
YOL042W |
Putative endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL41B |
YDL133C-A |
Ribosomal 60S subunit protein L41B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEG2 |
YKL105C |
Eisosome component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RKM3 |
YBR030W |
Ribosomal lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR220C |
YBR220C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
