Standard name Systematic name Name description Description
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth; PDR5 has a paralog, PDR15, that arose from the whole genome duplication
Visualize the interactome of PDR5
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 14

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.92 0.889 0.926
Cort. Patches NaN 0.134 0.150
Cytoplasm NaN 0.062 NaN
ER NaN 0.051 NaN

GFP localization & abundance

GFP localization GFP abundance
cell periphery 42000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PDR5 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 8 3 8 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 5 3 5 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter physical 5 2 4 Two-hybrid, PCA, PCA, PCA, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 4 2 4 Synthetic Growth Defect, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 4 2 2 Co-fractionation, PCA, PCA, PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 3 2 3 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network regulation 3 3 2 beta-galactosidase reporter gene assay evidence, DNAse footprinting evidence, northern blot evidence
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 3 1 2 PCA, PCA, PCA
YOL075C YOL075C Putative ABC transporter physical 3 1 1 PCA, PCA, PCA
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response regulation 2 2 2 beta-galactosidase reporter gene assay evidence, northern blot evidence
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 2 2 2 Two-hybrid, Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 2 2 2 Co-fractionation, PCA
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 2 2 2 Phenotypic Suppression, Negative Genetic
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 2 1 2 PCA, PCA
YML053C YML053C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 2 1 2 Negative Genetic, Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 2 1 2 Negative Genetic, Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane physical 2 2 1 Affinity Capture-Western, PCA
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking physical 2 2 1 Affinity Capture-Western, PCA
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
AIM41 YOR215C Protein of unknown function physical 2 1 1 PCA, PCA
SEO1 YAL067C Putative permease physical 2 1 1 PCA, PCA
SMF2 YHR050W Divalent metal ion transporter involved in manganese homeostasis physical 2 1 1 PCA, PCA
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 2 1 1 PCA, PCA
MCH5 YOR306C Plasma membrane riboflavin transporter physical 2 1 1 PCA, PCA
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 PCA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 1 1 1 Synthetic Growth Defect
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic physical 1 1 1 Affinity Capture-MS
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity genetic 1 1 1 Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane physical 1 1 1 Co-fractionation
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 PCA
HXT7 YDR342C High-affinity glucose transporter physical 1 1 1 Co-fractionation
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 PCA
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Synthetic Rescue
HXT5 YHR096C Hexose transporter with moderate affinity for glucose physical 1 1 1 PCA
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Phenotypic Enhancement
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Dosage Rescue
CSM3 YMR048W Replication fork associated factor physical 1 1 1 Affinity Capture-MS
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO3 YLR372W Elongase physical 1 1 1 PCA
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex physical 1 1 1 PCA
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence physical 1 1 1 Two-hybrid
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway physical 1 1 1 Two-hybrid
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols physical 1 1 1 Two-hybrid
RAX2 YLR084C Protein required for the maintenance of bud site selection physical 1 1 1 Two-hybrid
TMS1 YDR105C Vacuolar membrane protein of unknown function physical 1 1 1 Two-hybrid
YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Two-hybrid
UTP10 YJL109C Nucleolar protein physical 1 1 1 Two-hybrid
PTR2 YKR093W Integral membrane peptide transporter physical 1 1 1 Co-fractionation
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Co-fractionation
SUR7 YML052W Plasma membrane protein, component of eisosomes physical 1 1 1 Co-fractionation
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
YGR266W YGR266W Protein of unknown function physical 1 1 1 Co-fractionation
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 PCA
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane genetic 1 1 1 Phenotypic Enhancement
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RAS2 YNL098C GTP-binding protein physical 1 1 1 PCA
RTN1 YDR233C Reticulon protein physical 1 1 1 PCA
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 PCA
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth physical 1 1 1 PCA
YGR026W YGR026W Putative protein of unknown function physical 1 1 1 PCA
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 PCA
YND1 YER005W Apyrase with wide substrate specificity physical 1 1 1 PCA
YNL208W YNL208W Protein of unknown function physical 1 1 1 PCA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) physical 1 1 1 Two-hybrid
SPA2 YLL021W Component of the polarisome physical 1 1 1 Affinity Capture-Western
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Growth Defect
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Dosage Rescue
YPT31 YER031C Rab family GTPase genetic 1 1 1 Dosage Rescue
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Phenotypic Enhancement
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Phenotypic Suppression
RKM2 YDR198C Ribosomal protein lysine methyltransferase genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNK1 YKL067W Nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Synthetic Growth Defect
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 1 1 1 Negative Genetic
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p physical 1 1 1 Two-hybrid
NRT1 YOR071C High-affinity nicotinamide riboside transporter physical 1 1 1 Two-hybrid
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Biochemical Activity
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Phenotypic Enhancement
HOT13 YKL084W Zinc-binding mitochondrial intermembrane space (IMS) protein genetic 1 1 1 Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 1 1 1 Synthetic Growth Defect
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
FUN26 YAL022C High affinity, broad selectivity, nucleoside/nucleobase transporter physical 1 1 1 PCA
MRH1 YDR033W Protein that localizes primarily to the plasma membrane physical 1 1 1 Co-fractionation
NCE102 YPR149W Protein of unknown function physical 1 1 1 Co-fractionation
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Rescue
PDR15 YDR406W Plasma membrane ATP binding cassette (ABC) transporter genetic 1 1 1 Phenotypic Enhancement
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
COS1 YNL336W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
CCW12 YLR110C Cell wall mannoprotein physical 1 1 1 PCA
EMA19 YLR050C Integral ER membrane protein involved in protein sorting physical 1 1 1 PCA
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 1 1 1 Synthetic Rescue
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Phenotypic Enhancement