SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
genetic |
4 |
2 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue |
TRK2 |
YKR050W |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
RGT1 |
YKL038W |
Glucose-responsive transcription factor |
regulation |
2 |
2 |
2 |
beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence |
GAL2 |
YLR081W |
Galactose permease |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-Western |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
2 |
2 |
2 |
Protein-RNA, Affinity Capture-RNA |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
2 |
1 |
2 |
PCA, PCA |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
PLB1 |
YMR008C |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
JLP2 |
YMR132C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AIM24 |
YJR080C |
Protein with a role in determining mitochondrial architecture |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
CYC8 |
YBR112C |
General transcriptional co-repressor |
regulation |
1 |
1 |
1 |
beta-galactosidase reporter gene assay evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
beta-galactosidase reporter gene assay evidence |
WTM1 |
YOR230W |
Transcriptional modulator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
FTH1 |
YBR207W |
Putative high affinity iron transporter |
physical |
1 |
1 |
1 |
PCA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
PCA |
GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
1 |
1 |
1 |
PCA |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
physical |
1 |
1 |
1 |
PCA |
AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
physical |
1 |
1 |
1 |
PCA |
GPA2 |
YER020W |
Nucleotide binding alpha subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Proximity Label-MS |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
physical |
1 |
1 |
1 |
PCA |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
physical |
1 |
1 |
1 |
PCA |
ELO3 |
YLR372W |
Elongase |
physical |
1 |
1 |
1 |
PCA |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTT1 |
YIR038C |
ER associated glutathione S-transferase |
physical |
1 |
1 |
1 |
PCA |
APN2 |
YBL019W |
Class II abasic (AP) endonuclease involved in repair of DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASN2 |
YGR124W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
physical |
1 |
1 |
1 |
PCA |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FTR1 |
YER145C |
High affinity iron permease |
physical |
1 |
1 |
1 |
PCA |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP45 |
YDL222C |
Integral membrane protein localized to mitochondria |
physical |
1 |
1 |
1 |
PCA |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
RFS1 |
YBR052C |
Protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
SNA4 |
YDL123W |
Protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
SNQ2 |
YDR011W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
TVP15 |
YDR100W |
Integral membrane protein |
physical |
1 |
1 |
1 |
PCA |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
physical |
1 |
1 |
1 |
PCA |
PLM2 |
YDR501W |
Putative transcription factor, contains Forkhead Associated domain |
physical |
1 |
1 |
1 |
PCA |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
physical |
1 |
1 |
1 |
PCA |
SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
PCA |
PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
physical |
1 |
1 |
1 |
PCA |
SDS23 |
YGL056C |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
PCA |
KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
physical |
1 |
1 |
1 |
PCA |
MUP1 |
YGR055W |
High affinity methionine permease |
physical |
1 |
1 |
1 |
PCA |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
SNA3 |
YJL151C |
Protein involved in efficient MVB sorting of proteins to the vacuole |
physical |
1 |
1 |
1 |
PCA |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
PCA |
TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
SFK1 |
YKL051W |
Protein that regulates phospholipid asymmetry at plasma membrane |
physical |
1 |
1 |
1 |
PCA |
MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
physical |
1 |
1 |
1 |
PCA |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
YVH1 |
YIR026C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
PCA |
QDR2 |
YIL121W |
Plasma membrane transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
TPO3 |
YPR156C |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
physical |
1 |
1 |
1 |
PCA |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
physical |
1 |
1 |
1 |
PCA |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
PCA |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
physical |
1 |
1 |
1 |
PCA |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
PCA |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
1 |
1 |
1 |
PCA |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
physical |
1 |
1 |
1 |
PCA |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HXT4 |
YHR092C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HXT5 |
YHR096C |
Hexose transporter with moderate affinity for glucose |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HXT6 |
YDR343C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HXT7 |
YDR342C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PTC4 |
YBR125C |
Cytoplasmic type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PLB2 |
YMR006C |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM2 |
YDR502C |
S-adenosylmethionine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX1 |
YLR043C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEU9 |
YOR108W |
Alpha-isopropylmalate synthase II (2-isopropylmalate synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICP55 |
YER078C |
Mitochondrial aminopeptidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR016W |
YGR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI7 |
YDL104C |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBH1 |
YJL181W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML100W-A |
YML100W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
PCA |
BAP2 |
YBR068C |
High-affinity leucine permease |
physical |
1 |
1 |
1 |
PCA |
COT1 |
YOR316C |
Vacuolar transporter that mediates zinc transport into the vacuole |
physical |
1 |
1 |
1 |
PCA |