Standard name Systematic name Name description Description
APN2 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage Class II abasic (AP) endonuclease involved in repair of DNA damage; resolves blocked 3' ends that result from removal of misincorporated nucleotides; homolog of human HAP1 and E. coli exoIII
Visualize the interactome of APN2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.762 0.788 0.77
Mito 0.320 0.053 0.07
Vac/Vac Memb 0.113 0.250 0.23

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 414

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
APN2 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
APN1 YKL114C Major apurinic/apyrimidinic endonuclease genetic 17 4 16 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 7 2 7 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p) genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 3 1 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
TPP1 YMR156C DNA 3'-phosphatase genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 3 2 2 Two-hybrid, Co-purification, Two-hybrid
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
UNG1 YML021C Uracil-DNA glycosylase genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 2 2 1 Synthetic Lethality, Synthetic Rescue
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Lethality
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Phenotypic Suppression
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Phenotypic Enhancement
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
HNT3 YOR258W DNA 5' AMP hydrolase involved in DNA repair genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Lethality
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Lethality
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Lethality
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Phenotypic Enhancement
RAD24 YER173W Checkpoint protein genetic 1 1 1 Phenotypic Enhancement
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Phenotypic Enhancement
RAD51 YER095W Strand exchange protein genetic 1 1 1 Phenotypic Enhancement
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Phenotypic Enhancement
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SAW1 YAL027W 5'- and 3'-flap DNA binding protein genetic 1 1 1 Synthetic Lethality
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Negative Genetic
YKL106C-A YKL106C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
FMP27 YLR454W Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Lethality
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Rescue
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Synthetic Rescue
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic