Standard name Systematic name Name description Description
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA RNA binding protein required for maturation of tRNA and U6 snRNA; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen
Visualize the interactome of LHP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.974 0.984 0.955

GFP localization & abundance

GFP localization GFP abundance
nucleus no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LHP1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM7 YNL147W Lsm (Like Sm) protein genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
LSM6 YDR378C Lsm (Like Sm) protein genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MSC1 YML128C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 2 2 2 Reconstituted Complex, Protein-peptide
PAB1 YER165W Poly(A) binding protein physical 2 2 2 Affinity Capture-MS, Co-fractionation
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 2 2 2 Dosage Rescue, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
CDC33 YOL139C Translation initiation factor eIF4E physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SRP72 YPL210C Core component of the signal recognition particle (SRP) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 2 1 2 Negative Genetic, Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 2 1 2 Negative Genetic, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 2 Negative Genetic, Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 2 1 2 Negative Genetic, Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 2 1 2 Negative Genetic, Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Negative Genetic, Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 2 1 Phenotypic Suppression, Dosage Growth Defect
RNH70 YGR276C 3'-5' exoribonuclease genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 1 Negative Genetic, Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 2 1 1 Negative Genetic, Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 2 1 1 Negative Genetic, Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 2 1 1 Negative Genetic, Negative Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Affinity Capture-MS
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
PRP4 YPR178W Splicing factor physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein physical 1 1 1 Affinity Capture-MS
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Reconstituted Complex
WWM1 YFL010C WW domain containing protein of unknown function physical 1 1 1 Protein-peptide
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase physical 1 1 1 Protein-peptide
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Synthetic Rescue
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Lethality
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Synthetic Lethality
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Synthetic Growth Defect
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation genetic 1 1 1 Positive Genetic
TRM8 YDL201W Catalytic subunit of a tRNA methyltransferase complex genetic 1 1 1 Positive Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Positive Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Positive Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 1 1 1 Synthetic Growth Defect
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Negative Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Dosage Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Positive Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Protein-peptide
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex genetic 1 1 1 Positive Genetic
CUS2 YNL286W Putative checkpoint factor in transcription genetic 1 1 1 Negative Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Growth Defect
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic