Standard name Systematic name Name description Description
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis Protein involved in proteasomal and 40S ribosomal subunit biogenesis; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA; cleavage is activated by Fun12p, a GTPase and translation initiation factor; relocalizes from nucleus to nucleolus upon DNA replication stress
Visualize the interactome of NOB1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.954 0.979 0.983

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 4490

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NOB1 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 19 6 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 13 2 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 10 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 7 4 6 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Co-purification
LTV1 YKL143W Subunit of the EGO/GSE complex physical 6 4 6 Affinity Capture-MS, Reconstituted Complex, Co-fractionation, Co-purification, Affinity Capture-MS, Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 3 2 3 Affinity Capture-MS, Proximity Label-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 2 2 2 Negative Genetic, Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 2 1 2 Negative Genetic, Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 2 1 Affinity Capture-Western, Co-purification
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 2 2 1 Reconstituted Complex, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 1 1 1 Negative Genetic
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
GCN2 YDR283C Protein kinase physical 1 1 1 Reconstituted Complex
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Positive Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Positive Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Two-hybrid
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 1 1 1 Co-purification
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Reconstituted Complex
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-Western
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SCY1 YGL083W Putative kinase physical 1 1 1 Reconstituted Complex
YAK1 YJL141C Serine-threonine protein kinase physical 1 1 1 Reconstituted Complex
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Protein-peptide
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase physical 1 1 1 Protein-peptide
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Dosage Rescue
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Dosage Rescue
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p genetic 1 1 1 Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
UGA2 YBR006W Succinate semialdehyde dehydrogenase genetic 1 1 1 Positive Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
RPS26B YER131W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Positive Genetic
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
YBR225W YBR225W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme genetic 1 1 1 Negative Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
SKA1 YKL023W SKI complex-associated protein genetic 1 1 1 Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
PAU17 YLL025W Protein of unknown function genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
YPK2 YMR104C AGC-type S/T protein kinase genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Negative Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Synthetic Growth Defect
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Synthetic Growth Defect
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Synthetic Lethality
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Positive Genetic
DCI1 YOR180C Peroxisomal protein genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Reconstituted Complex
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Positive Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase genetic 1 1 1 Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) genetic 1 1 1 Negative Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 1 1 1 Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
BUD23 YCR047C Ribosome biogenesis factor physical 1 1 1 Affinity Capture-Western
BUD23 YCR047C Ribosome biogenesis factor genetic 1 1 1 Synthetic Rescue
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Positive Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
MAL31 YBR298C Maltose permease genetic 1 1 1 Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
NMA111 YNL123W Serine protease and general molecular chaperone genetic 1 1 1 Negative Genetic
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic