Standard name Systematic name Name description Description
PBP1 YGR178C Component of glucose deprivation induced stress granules Component of glucose deprivation induced stress granules; involved in P-body-dependent granule assembly; regulates TORC1 signaling and autophagy; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; similar to human ataxin-2
Visualize the interactome of PBP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.866 0.899 0.735
Vac/Vac Memb 0.177 0.138 0.366

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 2870

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PBP1 7 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 11 4 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
PBP4 YDL053C Pbp1p binding protein physical 5 2 4 Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 4 3 3 Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 4 2 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Lethality
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 3 3 Two-hybrid, PCA, Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-Western
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 3 3 2 Negative Genetic, Dosage Rescue, Synthetic Growth Defect
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 3 2 2 Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement
CIK1 YMR198W Kinesin-associated protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 2 2 2 Positive Genetic, Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 2 2 Proximity Label-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 2 2 2 Dosage Growth Defect, Synthetic Growth Defect
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Two-hybrid, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Positive Genetic, Positive Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
KOG1 YHR186C Subunit of TORC1 physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 2 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
IGO1 YNL157W Protein required for initiation of G0 program physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 2 1 Negative Genetic, Positive Genetic
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 2 2 1 Two-hybrid, Affinity Capture-Western
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 2 2 1 Two-hybrid, Affinity Capture-Western
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 2 1 Synthetic Rescue, Dosage Lethality
JHD2 YJR119C JmjC domain family histone demethylase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 2 1 1 Negative Genetic, Negative Genetic
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 1 1 Negative Genetic, Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 1 1 Negative Genetic, Negative Genetic
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 2 1 1 Negative Genetic, Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 2 1 1 Negative Genetic, Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 2 1 1 Negative Genetic, Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 2 1 1 Negative Genetic, Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 2 1 1 Negative Genetic, Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Synthetic Growth Defect
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein physical 1 1 1 Affinity Capture-MS
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex physical 1 1 1 Two-hybrid
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex physical 1 1 1 Affinity Capture-MS
LIN1 YHR156C Non-essential component of U5 snRNP genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Two-hybrid
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Positive Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 1 1 1 Synthetic Growth Defect
LTV1 YKL143W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 PCA
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Positive Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Phenotypic Suppression
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 PCA
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Negative Genetic
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Phenotypic Enhancement
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Phenotypic Suppression
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Positive Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Synthetic Rescue
MUD2 YKL074C Protein involved in early pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation physical 1 1 1 Two-hybrid
FIR1 YER032W Protein involved in 3' mRNA processing physical 1 1 1 Two-hybrid
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase physical 1 1 1 Two-hybrid
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor physical 1 1 1 Affinity Capture-MS
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
YNR014W YNR014W Putative protein of unknown function physical 1 1 1 Two-hybrid
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-Western
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Dosage Rescue
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Phenotypic Suppression
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
SET4 YJL105W Chromatin-associated protein involved in control of stress response physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-Western
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Dosage Rescue
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Positive Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Growth Defect
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Synthetic Growth Defect
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Positive Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Positive Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
PEX7 YDR142C Peroxisomal signal receptor for peroxisomal matrix proteins genetic 1 1 1 Positive Genetic
UPS2 YLR168C Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A genetic 1 1 1 Negative Genetic
SEN2 YLR105C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
YJL118W YJL118W Protein of unknown function genetic 1 1 1 Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
YMR030W-A YMR030W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RPL18B YNL301C Ribosomal 60S subunit protein L18B genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Dosage Rescue
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 1 1 1 Dosage Rescue
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Phenotypic Suppression
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Phenotypic Suppression
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Dosage Rescue
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Dosage Rescue
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Dosage Rescue
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Affinity Capture-MS
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
HUB1 YNR032C-A Ubiquitin-like protein modifier physical 1 1 1 Affinity Capture-MS
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
HVG1 YER039C Protein of unknown function genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Dosage Rescue
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic