Standard name Systematic name Name description Description
FIR1 YER032W Protein involved in 3' mRNA processing Protein involved in 3' mRNA processing; interacts with Ref2p; APCC(Cdh1) substrate; potential Cdc28p substrate
Visualize the interactome of FIR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 69

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.824 NaN 0.892
Mito 0.078 NaN 0.054
Peroxisome 0.059 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
bud neck low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FIR1 3 0 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 5 4 3 Two-hybrid, Affinity Capture-MS, Two-hybrid, Protein-peptide, Reconstituted Complex
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor regulation 3 3 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
CBF2 YGR140W Essential kinetochore protein physical 2 1 2 Two-hybrid, Two-hybrid
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex physical 2 1 2 Two-hybrid, Two-hybrid
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 2 1 2 Negative Genetic, Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 2 1 2 Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 1 2 Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 1 2 Negative Genetic, Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 2 1 2 Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network regulation 1 1 1 protein kinase assay evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BUD14 YAR014C Protein involved in bud-site selection physical 1 1 1 Two-hybrid
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Two-hybrid
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Two-hybrid
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Two-hybrid
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Phenotypic Enhancement
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Positive Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex physical 1 1 1 Two-hybrid
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Two-hybrid
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) physical 1 1 1 Two-hybrid
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein physical 1 1 1 Two-hybrid
REF2 YDR195W RNA-binding protein genetic 1 1 1 Phenotypic Enhancement
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Two-hybrid
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Two-hybrid
PRP45 YAL032C Protein required for pre-mRNA splicing physical 1 1 1 Two-hybrid
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 1 1 1 Two-hybrid
YLR456W YLR456W Protein of unknown function physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Two-hybrid
SPT2 YER161C Protein involved in negative regulation of transcription physical 1 1 1 Reconstituted Complex
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 Two-hybrid
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
YEN1 YER041W Holliday junction resolvase physical 1 1 1 Two-hybrid
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Synthetic Lethality
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Negative Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Dosage Rescue
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
PRE3 YJL001W Beta 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Synthetic Lethality
LRE1 YCL051W Protein involved in control of cell wall structure and stress response genetic 1 1 1 Synthetic Growth Defect
ACF2 YLR144C Intracellular beta-1,3-endoglucanase physical 1 1 1 Affinity Capture-MS
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Synthetic Lethality
CTS1 YLR286C Endochitinase genetic 1 1 1 Synthetic Rescue