Standard name Systematic name Name description Description
LRE1 YCL051W Protein involved in control of cell wall structure and stress response Protein involved in control of cell wall structure and stress response; direct inhibitor of the nuclear Dbf2 related (NDR) kinase Cbk1p-Mob2p; overproduction confers resistance to cell-wall degrading enzymes; exhibits genetic interactions with genes involved in the cell wall integrity pathway; LRE1 has a paralog, HLR1, that arose from the whole genome duplication
Visualize the interactome of LRE1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LRE1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 7 5 4 Two-hybrid, Two-hybrid, PCA, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Co-localization
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 3 2 2 Biochemical Activity, Affinity Capture-Western, Biochemical Activity
MOB2 YFL034C-B Activator of Cbk1p kinase physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 2 1 2 Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 2 1 2 Negative Genetic, Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 2 1 2 Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SSD1 YDR293C Translational repressor physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 2 1 2 Negative Genetic, Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 1 Two-hybrid, Biochemical Activity
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 2 1 1 Dosage Rescue, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Two-hybrid
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
AVT4 YNL101W Vacuolar transporter genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Phenotypic Suppression
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Rescue
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-Western
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Negative Genetic
FIR1 YER032W Protein involved in 3' mRNA processing genetic 1 1 1 Synthetic Growth Defect
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Dosage Rescue
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Dosage Rescue
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Synthetic Growth Defect
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Dosage Rescue
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Dosage Rescue
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Dosage Rescue
MRS6 YOR370C Rab escort protein genetic 1 1 1 Dosage Rescue
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Dosage Rescue
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
SCO2 YBR024W Protein anchored to mitochondrial inner membrane genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Dosage Rescue
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Dosage Rescue
MYO1 YHR023W Type II myosin heavy chain genetic 1 1 1 Synthetic Growth Defect
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
VFA1 YER128W Protein that interacts with Vps4p and has a role in vacuolar sorting genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Dosage Rescue