GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	physical	14	3	13	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-localization, Affinity Capture-MS
VPS72	YDR485C	Htz1p-binding component of the SWR1 complex	genetic	12	3	9	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS71	YML041C	Nucleosome-binding component of the SWR1 complex	genetic	11	2	9	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	10	2	8	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HTZ1	YOL012C	Histone variant H2AZ	genetic	9	3	8	Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ARP6	YLR085C	Actin-related protein that binds nucleosomes	genetic	9	2	6	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	genetic	9	2	6	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	physical	8	3	7	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
SWC5	YBR231C	Component of the SWR1 complex	genetic	8	3	7	Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SET3	YKR029C	Defining member of the SET3 histone deacetylase complex	genetic	8	2	7	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	8	3	6	Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	8	1	6	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWC3	YAL011W	Protein of unknown function	genetic	8	3	5	Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BRE1	YDL074C	E3 ubiquitin ligase	genetic	8	2	5	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CDC73	YLR418C	Component of the Paf1p complex	genetic	7	3	6	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	7	1	6	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LTE1	YAL024C	Protein similar to GDP/GTP exchange factors	genetic	7	3	5	Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GET1	YGL020C	Subunit of the GET complex	genetic	7	2	5	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ELP4	YPL101W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	7	2	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LEO1	YOR123C	Component of the Paf1 complex	genetic	7	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RTT109	YLL002W	Histone acetyltransferase	genetic	7	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HDA1	YNL021W	Catalytic subunit of class II HDA1 histone deacetylase complex	genetic	7	4	4	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Positive Genetic
ARP8	YOR141C	Nuclear actin-related protein involved in chromatin remodeling	genetic	6	2	5	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	physical	6	2	5	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ELP6	YMR312W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	6	2	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SAC3	YDR159W	mRNA export factor	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP6	YFR010W	Ubiquitin-specific protease	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOS2	YGL194C	Histone deacetylase and subunit of Set3 and Rpd3L complexes	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSF1	YLR087C	Protein with structural similarity to lipid transport protein Vps13p	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HHT1	YBR010W	Histone H3	physical	6	3	4	Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide
ELP2	YGR200C	Subunit of Elongator complex	genetic	6	2	4	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HDA3	YPR179C	Subunit of HDA1 histone deacetylase complex	genetic	6	3	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement
RXT2	YBR095C	Component of the histone deacetylase Rpd3L complex	genetic	5	2	5	Phenotypic Suppression, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	genetic	5	2	5	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP3	YPL086C	Subunit of Elongator complex	genetic	5	2	5	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IXR1	YKL032C	Transcriptional repressor that regulates hypoxic genes during normoxia	genetic	5	2	5	Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHD1	YER164W	Chromatin remodeler that regulates various aspects of transcription	genetic	5	1	5	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
NHP10	YDL002C	Non-essential INO80 chromatin remodeling complex subunit	genetic	5	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1	YLR039C	Protein involved in retrograde transport to the cis-Golgi network	genetic	5	1	5	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
HHT1	YBR010W	Histone H3	genetic	5	3	4	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Negative Genetic
TIM18	YOR297C	Component of the mitochondrial TIM22 complex	genetic	5	2	4	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	genetic	5	2	4	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	5	2	4	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
UBA4	YHR111W	E1-like protein that activates Urm1p before urmylation	genetic	5	2	4	Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET2	YER083C	Subunit of the GET complex	genetic	5	2	4	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
EAF3	YPR023C	Component of the Rpd3S histone deacetylase complex	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SNT1	YCR033W	Set3C histone deacetylase scaffold	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
STB5	YHR178W	Transcription factor	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BCK1	YJL095W	MAPKKK acting in the protein kinase C signaling pathway	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO2	YDR123C	Transcription factor	genetic	5	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	genetic	5	3	3	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Positive Genetic
SWD1	YAR003W	Subunit of the COMPASS (Set1C) complex	genetic	5	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
BRE2	YLR015W	Subunit of COMPASS (Set1C) complex	genetic	5	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
HHT2	YNL031C	Histone H3	physical	5	2	3	Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	5	2	2	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ADA2	YDR448W	Transcription coactivator	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	genetic	5	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
CTK1	YKL139W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I)	genetic	4	3	4	Phenotypic Enhancement, Negative Genetic, Negative Genetic, Positive Genetic
RPN10	YHR200W	Proteasome polyubiquitin receptor	genetic	4	3	4	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue
SUB1	YMR039C	Transcriptional regulator	genetic	4	3	4	Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	genetic	4	3	4	Phenotypic Suppression, Positive Genetic, Synthetic Rescue, Positive Genetic
TOP1	YOL006C	Topoisomerase I	genetic	4	3	4	Phenotypic Suppression, Positive Genetic, Synthetic Growth Defect, Positive Genetic
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	physical	4	2	4	Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RXT2	YBR095C	Component of the histone deacetylase Rpd3L complex	physical	4	2	4	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PRP4	YPR178W	Splicing factor	genetic	4	2	4	Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
SGF11	YPL047W	Integral subunit of SAGA histone acetyltransferase complex	genetic	4	2	4	Positive Genetic, Synthetic Rescue, Positive Genetic, Positive Genetic
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO4	YOL108C	Transcription factor involved in phospholipid synthesis	genetic	4	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	4	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SCS7	YMR272C	Sphingolipid alpha-hydroxylase	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIF2	YBR103W	WD40 repeat-containing subunit of Set3C histone deacetylase complex	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLX5	YDL013W	Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex	genetic	4	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
RIM101	YHL027W	Cys2His2 zinc-finger transcriptional repressor	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IKI1	YHR187W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RVS161	YCR009C	Amphiphysin-like lipid raft protein	genetic	4	3	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
RVS167	YDR388W	Calmodulin-binding actin-associated protein	genetic	4	3	3	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
IKI3	YLR384C	Subunit of Elongator complex	genetic	4	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ARC18	YLR370C	Subunit of the ARP2/3 complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
EDE1	YBL047C	Scaffold protein involved in the formation of early endocytic sites	genetic	4	2	3	Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Enhancement
RSC1	YGR056W	Component of the RSC chromatin remodeling complex	genetic	4	2	3	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PRM6	YML047C	Potassium transporter that mediates K+ influx	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
TCP1	YDR212W	Alpha subunit of chaperonin-containing T-complex	genetic	4	2	3	Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
RTF1	YGL244W	Subunit of RNAPII-associated chromatin remodeling Paf1 complex	genetic	4	2	3	Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic
PHO80	YOL001W	Cyclin	genetic	4	2	3	Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic
APQ12	YIL040W	Nuclear envelope/ER integral membrane protein	genetic	4	2	3	Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic
ASF1	YJL115W	Nucleosome assembly factor	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	genetic	4	1	3	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
TIM13	YGR181W	Mitochondrial intermembrane space protein	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UPS1	YLR193C	Phosphatidic acid transfer protein	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRO7	YPR032W	Effector of Rab GTPase Sec4p	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3	YJR073C	Methylene-fatty-acyl-phospholipid synthase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OMS1	YDR316W	Protein integral to the mitochondrial membrane	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BUD27	YFL023W	Unconventional prefoldin protein involved in translation initiation	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
FKH1	YIL131C	Forkhead family transcription factor	regulation	3	2	3	chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
HAP5	YOR358W	Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex	genetic	3	2	3	Phenotypic Enhancement, Negative Genetic, Negative Genetic
LSM6	YDR378C	Lsm (Like Sm) protein	genetic	3	2	3	Positive Genetic, Negative Genetic, Positive Genetic
NRD1	YNL251C	RNA-binding subunit of Nrd1 complex	genetic	3	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	genetic	3	2	3	Synthetic Lethality, Negative Genetic, Negative Genetic
URE2	YNL229C	Nitrogen catabolite repression transcriptional regulator	genetic	3	2	3	Phenotypic Enhancement, Negative Genetic, Negative Genetic
BIM1	YER016W	Microtubule plus end-tracking protein	genetic	3	2	3	Synthetic Lethality, Negative Genetic, Synthetic Lethality
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
CSE2	YNR010W	Subunit of the RNA polymerase II mediator complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
VPS8	YAL002W	Membrane-binding component of the CORVET complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SEC22	YLR268W	R-SNARE protein	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SAM37	YMR060C	Component of the Sorting and Assembly Machinery (SAM) complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
THP2	YHR167W	Subunit of the THO and TREX complexes	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
XRN1	YGL173C	Evolutionarily-conserved 5'-3' exonuclease	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
YPT6	YLR262C	Rab family GTPase	genetic	3	1	3	Positive Genetic, Positive Genetic, Positive Genetic
SSN3	YPL042C	Component of the RNA polymerase II mediator complex	genetic	3	1	3	Positive Genetic, Positive Genetic, Positive Genetic
SWI5	YDR146C	Transcription factor that recruits Mediator and Swi/Snf complexes	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SDC1	YDR469W	Subunit of the COMPASS (Set1C) complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
MNN10	YDR245W	Subunit of a Golgi mannosyltransferase complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
BUB1	YGR188C	Protein kinase involved in the cell cycle checkpoint into anaphase	genetic	3	1	3	Positive Genetic, Positive Genetic, Positive Genetic
MMM1	YLL006W	ER integral membrane protein, ERMES complex subunit	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
GLC7	YER133W	Type 1 S/T protein phosphatase (PP1) catalytic subunit	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
BDF1	YLR399C	BET family transcriptional regulator	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
AAT2	YLR027C	Cytosolic aspartate aminotransferase involved in nitrogen metabolism	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PFY1	YOR122C	Profilin	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
GWT1	YJL091C	Protein involved in the inositol acylation of GlcN-PI	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
EFT2	YDR385W	Elongation factor 2 (EF-2), also encoded by EFT1	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ERG26	YGL001C	C-3 sterol dehydrogenase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
UME1	YPL139C	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	physical	3	1	2	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SCO2	YBR024W	Protein anchored to mitochondrial inner membrane	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SEC66	YBR171W	Non-essential subunit of Sec63 complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SWF1	YDR126W	Palmitoyltransferase that acts on transmembrane proteins	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
QCR6	YFR033C	Subunit 6 of the ubiquinol cytochrome-c reductase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RPN12	YFR052W	Subunit of the 19S regulatory particle of the 26S proteasome lid	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTG2	YGL252C	Sensor of mitochondrial dysfunction	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
QCR9	YGR183C	Subunit 9 of ubiquinol cytochrome-c reductase (Complex III)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SMI1	YGR229C	Protein involved in the regulation of cell wall synthesis	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SDH2	YLL041C	Iron-sulfur protein subunit of succinate dehydrogenase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
POM34	YLR018C	Subunit of the transmembrane ring of the nuclear pore complex (NPC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SEC61	YLR378C	Conserved ER protein translocation channel	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
VPS9	YML097C	Guanine nucleotide exchange factor (GEF) and ubiquitin receptor	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RIM13	YMR154C	Calpain-like cysteine protease	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
YDL157C	YDL157C	Putative protein of unknown function	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
THI3	YDL080C	Regulatory protein that binds Pdc2p and Thi2p transcription factors	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTR1	YER139C	Dual specificity protein phosphatase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RCF1	YML030W	Cytochrome c oxidase subunit	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
TSA1	YML028W	Thioredoxin peroxidase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTC6	YPL183W-A	Protein involved in translation	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RPO31	YOR116C	RNA polymerase III largest subunit C160	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MAF1	YDR005C	Highly conserved negative regulator of RNA polymerase III	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
HOS4	YIL112W	Subunit of the Set3 complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NAT1	YDL040C	Subunit of protein N-terminal acetyltransferase NatA	genetic	3	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
IRA2	YOL081W	GTPase-activating protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CPR6	YLR216C	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
FUM1	YPL262W	Fumarase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LHS1	YKL073W	Molecular chaperone of the endoplasmic reticulum lumen	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ARP1	YHR129C	Actin-related protein of the dynactin complex	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
ATG16	YMR159C	Conserved protein involved in autophagy	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
FOB1	YDR110W	Nucleolar protein that binds the rDNA replication fork barrier site	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
KTI12	YKL110C	Protein that plays a role in modification of tRNA wobble nucleosides	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CPR7	YJR032W	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
NUP188	YML103C	Subunit of the inner ring of the nuclear pore complex (NPC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MCR1	YKL150W	Mitochondrial NADH-cytochrome b5 reductase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CRF1	YDR223W	Transcriptional corepressor	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MRC1	YCL061C	S-phase checkpoint protein required for DNA replication	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MSS1	YMR023C	Mitochondrial protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
JID1	YPR061C	Probable Hsp40p co-chaperone	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
DGA1	YOR245C	Diacylglycerol acyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
COX10	YPL172C	Heme A:farnesyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CYT1	YOR065W	Cytochrome c1	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LDB18	YLL049W	Component of the dynactin complex	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
COX7	YMR256C	Subunit VII of cytochrome c oxidase (Complex IV)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
EMI1	YDR512C	Non-essential protein of unknown function	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MTO1	YGL236C	Mitochondrial protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CMC1	YKL137W	Copper-binding protein of the mitochondrial intermembrane space	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
GPI1	YGR216C	Membrane protein involved in the synthesis of GlcNAc-PI	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LAS21	YJL062W	Mannose-ethanolamine phosphotransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ICE2	YIL090W	Integral ER membrane protein with type-III transmembrane domains	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LAS17	YOR181W	Actin assembly factor	genetic	3	2	1	Positive Genetic, Negative Genetic, Negative Genetic
MOB2	YFL034C-B	Activator of Cbk1p kinase	genetic	3	2	1	Positive Genetic, Negative Genetic, Negative Genetic
NPL3	YDR432W	RNA-binding protein	genetic	2	2	2	Negative Genetic, Synthetic Growth Defect
MED7	YOL135C	Subunit of the RNA polymerase II mediator complex	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
NOT3	YIL038C	Component of the CCR4-NOT core complex, involved in mRNA decapping	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
SRP1	YNL189W	Karyopherin alpha homolog	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
PKR1	YMR123W	V-ATPase assembly factor	genetic	2	2	2	Phenotypic Enhancement, Positive Genetic
SLM3	YDL033C	tRNA-specific 2-thiouridylase	genetic	2	2	2	Negative Genetic, Positive Genetic
RAD55	YDR076W	Protein that stimulates strand exchange	genetic	2	2	2	Negative Genetic, Synthetic Growth Defect
URM1	YIL008W	Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
SLX8	YER116C	Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex	genetic	2	2	2	Positive Genetic, Negative Genetic
PRE9	YGR135W	Alpha 3 subunit of the 20S proteasome	genetic	2	2	2	Synthetic Rescue, Negative Genetic
SPT2	YER161C	Protein involved in negative regulation of transcription	genetic	2	2	2	Negative Genetic, Positive Genetic
RPB2	YOR151C	RNA polymerase II second largest subunit B150	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
GAS1	YMR307W	Beta-1,3-glucanosyltransferase required for cell wall assembly	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	genetic	2	2	2	Phenotypic Suppression, Positive Genetic
IPL1	YPL209C	Aurora kinase of chromosomal passenger complex	genetic	2	2	2	Negative Genetic, Synthetic Rescue
MEX67	YPL169C	Poly(A)RNA binding protein involved in nuclear mRNA export	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
ERG2	YMR202W	C-8 sterol isomerase	genetic	2	2	2	Phenotypic Suppression, Positive Genetic
CKB1	YGL019W	Beta regulatory subunit of casein kinase 2 (CK2)	genetic	2	1	2	Positive Genetic, Positive Genetic
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	2	1	2	Negative Genetic, Negative Genetic
MFT1	YML062C	Subunit of the THO complex	genetic	2	1	2	Negative Genetic, Negative Genetic
ALA1	YOR335C	Cytoplasmic and mitochondrial alanyl-tRNA synthetase	genetic	2	1	2	Negative Genetic, Negative Genetic
ECM16	YMR128W	Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
HGH1	YGR187C	Chaperone protein for translation factor eEF2	genetic	2	1	2	Negative Genetic, Negative Genetic
AEP2	YMR282C	Mitochondrial protein	genetic	2	1	2	Negative Genetic, Negative Genetic
LSM7	YNL147W	Lsm (Like Sm) protein	genetic	2	1	2	Positive Genetic, Positive Genetic
MAK3	YPR051W	Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT)	genetic	2	1	2	Negative Genetic, Negative Genetic
MED11	YMR112C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	2	Negative Genetic, Negative Genetic
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
GEP3	YOR205C	Protein required for mitochondrial ribosome small subunit biogenesis	genetic	2	1	2	Negative Genetic, Negative Genetic
MUM2	YBR057C	Protein essential for meiotic DNA replication and sporulation	genetic	2	1	2	Negative Genetic, Negative Genetic
MYO2	YOR326W	Type V myosin motor involved in actin-based transport of cargos	genetic	2	1	2	Negative Genetic, Negative Genetic
MIS1	YBR084W	Mitochondrial C1-tetrahydrofolate synthase	genetic	2	1	2	Negative Genetic, Negative Genetic
IES5	YER092W	Non-essential INO80 chromatin remodeling complex subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
PDB1	YBR221C	E1 beta subunit of the pyruvate dehydrogenase (PDH) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
HSP82	YPL240C	Hsp90 chaperone	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	genetic	2	1	2	Positive Genetic, Positive Genetic
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	genetic	2	1	2	Positive Genetic, Positive Genetic
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	genetic	2	1	2	Positive Genetic, Positive Genetic
SRO9	YCL037C	Cytoplasmic RNA-binding protein	genetic	2	1	2	Negative Genetic, Negative Genetic
SNU66	YOR308C	Component of the U4/U6.U5 snRNP complex	genetic	2	1	2	Negative Genetic, Negative Genetic
THP1	YOL072W	Nuclear pore-associated protein	genetic	2	1	2	Negative Genetic, Negative Genetic
SOH1	YGL127C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	2	Negative Genetic, Negative Genetic
SEM1	YDR363W-A	19S proteasome regulatory particle lid subcomplex component	genetic	2	1	2	Negative Genetic, Negative Genetic
RIM21	YNL294C	pH sensor molecule, component of the RIM101 pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
SNF5	YBR289W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RTT103	YDR289C	Protein involved in transcription termination by RNA polymerase II	genetic	2	1	2	Negative Genetic, Negative Genetic
SSD1	YDR293C	Translational repressor	genetic	2	1	2	Negative Genetic, Negative Genetic
UMP1	YBR173C	Chaperone required for correct maturation of the 20S proteasome	genetic	2	1	2	Negative Genetic, Negative Genetic
SAS5	YOR213C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p)	genetic	2	1	2	Negative Genetic, Negative Genetic
VID22	YLR373C	G-quadruplex (G4) DNA binding protein	genetic	2	1	2	Positive Genetic, Positive Genetic
SSN8	YNL025C	Cyclin-like component of RNA polymerase II holoenzyme	genetic	2	1	2	Positive Genetic, Positive Genetic
SSN2	YDR443C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	2	Positive Genetic, Positive Genetic
SRP40	YKR092C	Nucleolar serine-rich protein	genetic	2	1	2	Positive Genetic, Positive Genetic
POL3	YDL102W	Catalytic subunit of DNA polymerase delta	genetic	2	1	2	Positive Genetic, Positive Genetic
RML2	YEL050C	Mitochondrial ribosomal protein of the large subunit (L2)	genetic	2	1	2	Negative Genetic, Negative Genetic
UTR2	YEL040W	Chitin transglycosylase	genetic	2	1	2	Negative Genetic, Negative Genetic
SWI3	YJL176C	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
POB3	YML069W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	genetic	2	1	2	Negative Genetic, Negative Genetic
RNA1	YMR235C	GTPase activating protein (GAP) for Gsp1p	genetic	2	1	2	Negative Genetic, Negative Genetic
YKU70	YMR284W	Subunit of the telomeric Ku complex (Yku70p-Yku80p)	genetic	2	1	2	Negative Genetic, Negative Genetic
YAL065C	YAL065C	Putative protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
PMT2	YAL023C	Protein O-mannosyltransferase of the ER membrane	genetic	2	1	2	Negative Genetic, Negative Genetic
YEL1	YBL060W	Guanine nucleotide exchange factor specific for Arf3p	genetic	2	1	2	Negative Genetic, Negative Genetic
STE50	YCL032W	Adaptor protein for various signaling pathways	genetic	2	1	2	Negative Genetic, Negative Genetic
SGF29	YCL010C	Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes	genetic	2	1	2	Positive Genetic, Positive Genetic
VPS41	YDR080W	Subunit of the HOPS endocytic tethering complex	genetic	2	1	2	Negative Genetic, Negative Genetic
SUM1	YDR310C	Transcriptional repressor that regulates middle-sporulation genes	genetic	2	1	2	Negative Genetic, Negative Genetic
RPL27B	YDR471W	Ribosomal 60S subunit protein L27B	genetic	2	1	2	Negative Genetic, Negative Genetic
YCH1	YGR203W	Phosphatase with sequence similarity to Mih1p	genetic	2	1	2	Negative Genetic, Negative Genetic
TDA10	YGR205W	ATP-binding protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
YIR042C	YIR042C	Putative protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
TIF2	YJL138C	Translation initiation factor eIF4A	genetic	2	1	2	Negative Genetic, Negative Genetic
SFC1	YJR095W	Mitochondrial succinate-fumarate transporter	genetic	2	1	2	Negative Genetic, Negative Genetic
YKL069W	YKL069W	Methionine-R-sulfoxide reductase	genetic	2	1	2	Negative Genetic, Negative Genetic
RPL14A	YKL006W	Ribosomal 60S subunit protein L14A	genetic	2	1	2	Positive Genetic, Positive Genetic
SAP190	YKR028W	Protein that forms a complex with the Sit4p protein phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
SKG1	YKR100C	Transmembrane protein with a role in cell wall polymer composition	genetic	2	1	2	Negative Genetic, Negative Genetic
SSO2	YMR183C	Plasma membrane t-SNARE	genetic	2	1	2	Positive Genetic, Positive Genetic
RCE1	YMR274C	Type II CAAX prenyl protease	genetic	2	1	2	Negative Genetic, Negative Genetic
VPS21	YOR089C	Endosomal Rab family GTPase	genetic	2	1	2	Negative Genetic, Negative Genetic
PNT1	YOR266W	Mitochondrial integral inner membrane protein	genetic	2	1	2	Negative Genetic, Negative Genetic
SPP1	YPL138C	Subunit of COMPASS (Set1C)	genetic	2	1	2	Negative Genetic, Negative Genetic
RLM1	YPL089C	MADS-box transcription factor	genetic	2	1	2	Negative Genetic, Negative Genetic
YME1	YPR024W	Catalytic subunit of i-AAA protease complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RPT4	YOR259C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	2	Negative Genetic, Negative Genetic
SUV3	YPL029W	ATP-dependent RNA helicase	genetic	2	1	2	Negative Genetic, Negative Genetic
RCO1	YMR075W	Essential component of the Rpd3S histone deacetylase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PPH21	YDL134C	Catalytic subunit of protein phosphatase 2A, PP2A	genetic	2	1	2	Positive Genetic, Positive Genetic
RTG1	YOL067C	Transcription factor (bHLH) involved in interorganelle communication	genetic	2	1	2	Negative Genetic, Negative Genetic
SET1	YHR119W	Histone methyltransferase, subunit of the COMPASS (Set1C) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
SAC1	YKL212W	Phosphatidylinositol phosphate phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
VPS1	YKR001C	Dynamin-like GTPase required for vacuolar sorting	genetic	2	1	2	Positive Genetic, Positive Genetic
CTI6	YPL181W	Component of the Rpd3L histone deacetylase complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
DUG1	YFR044C	Cys-Gly metallo-di-peptidase	genetic	2	1	2	Negative Genetic, Negative Genetic
MGE1	YOR232W	Mitochondrial matrix cochaperone	genetic	2	1	2	Negative Genetic, Negative Genetic
MDM30	YLR368W	F-box component of an SCF ubiquitin protein ligase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
CTF4	YPR135W	Chromatin-associated protein	genetic	2	1	2	Negative Genetic, Negative Genetic
BEM4	YPL161C	Protein involved in establishment of cell polarity and bud emergence	genetic	2	1	2	Negative Genetic, Negative Genetic
HXT5	YHR096C	Hexose transporter with moderate affinity for glucose	genetic	2	1	2	Negative Genetic, Negative Genetic
FKH2	YNL068C	Forkhead family transcription factor	genetic	2	1	2	Negative Genetic, Negative Genetic
MEH1	YKR007W	Subunit of the EGO/GSE complex	genetic	2	1	2	Positive Genetic, Positive Genetic
NUP133	YKR082W	Subunit of Nup84p subcomplex of nuclear pore complex (NPC)	genetic	2	1	2	Negative Genetic, Negative Genetic
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	2	1	2	Negative Genetic, Negative Genetic
CTK3	YML112W	Gamma subunit of C-terminal domain kinase I	genetic	2	1	2	Negative Genetic, Negative Genetic
NUP57	YGR119C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX14	YGL153W	Central component of the peroxisomal importomer complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX10	YDR265W	Peroxisomal membrane E3 ubiquitin ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX13	YLR191W	Peroxisomal importomer complex component	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX2	YJL210W	RING-finger peroxin and E3 ubiquitin ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
IES3	YLR052W	Subunit of the INO80 chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
ELO2	YCR034W	Fatty acid elongase, involved in sphingolipid biosynthesis	genetic	2	1	2	Negative Genetic, Negative Genetic
MDM12	YOL009C	Mitochondrial outer membrane protein, ERMES complex subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
DPH1	YIL103W	Protein required for synthesis of diphthamide	genetic	2	1	2	Negative Genetic, Negative Genetic
HAP4	YKL109W	Transcription factor	genetic	2	1	2	Negative Genetic, Negative Genetic
CSG2	YBR036C	Endoplasmic reticulum membrane protein	genetic	2	1	2	Positive Genetic, Positive Genetic
ASH1	YKL185W	Component of the Rpd3L histone deacetylase complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
MIP1	YOR330C	Mitochondrial DNA polymerase gamma	genetic	2	1	2	Negative Genetic, Negative Genetic
ECM21	YBL101C	Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p	genetic	2	1	2	Negative Genetic, Negative Genetic
PAM17	YKR065C	Constituent of the TIM23 complex	genetic	2	1	2	Negative Genetic, Negative Genetic
KEX1	YGL203C	Cell death protease essential for hypochlorite-induced apoptosis	genetic	2	1	2	Negative Genetic, Negative Genetic
ICL1	YER065C	Isocitrate lyase	genetic	2	1	2	Negative Genetic, Negative Genetic
MAK31	YCR020C-A	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type	genetic	2	1	2	Negative Genetic, Negative Genetic
IFM1	YOL023W	Mitochondrial translation initiation factor 2	genetic	2	1	2	Negative Genetic, Negative Genetic
COX8	YLR395C	Subunit VIII of cytochrome c oxidase (Complex IV)	genetic	2	1	2	Negative Genetic, Negative Genetic
MDM35	YKL053C-A	Mitochondrial intermembrane space protein	genetic	2	1	2	Positive Genetic, Positive Genetic
MIC12	YBR262C	Component of the MICOS complex	genetic	2	1	2	Negative Genetic, Negative Genetic
CRD1	YDL142C	Cardiolipin synthase	genetic	2	1	2	Negative Genetic, Negative Genetic
CYT2	YKL087C	Cytochrome c1 heme lyase	genetic	2	1	2	Negative Genetic, Negative Genetic
MCT1	YOR221C	Predicted malonyl-CoA:ACP transferase	genetic	2	1	2	Positive Genetic, Positive Genetic
DCV1	YFR012W	Protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
COA6	YMR244C-A	Protein involved in cytochrome c oxidase (Complex IV) assembly	genetic	2	1	2	Negative Genetic, Negative Genetic
FMT1	YBL013W	Methionyl-tRNA formyltransferase	genetic	2	1	2	Negative Genetic, Negative Genetic
BIR1	YJR089W	Subunit of chromosomal passenger complex (CPC)	genetic	2	2	1	Positive Genetic, Negative Genetic
HMT1	YBR034C	Nuclear SAM-dependent mono- and asymmetric methyltransferase	genetic	2	2	1	Negative Genetic, Synthetic Growth Defect
NSE5	YML023C	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ARP3	YJR065C	Essential component of the Arp2/3 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
BET2	YPR176C	Beta subunit of Type II geranylgeranyltransferase	genetic	2	1	1	Negative Genetic, Negative Genetic
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
EXO84	YBR102C	Exocyst subunit with dual roles in exocytosis and spliceosome assembly	genetic	2	1	1	Negative Genetic, Negative Genetic
GDI1	YER136W	GDP dissociation inhibitor	genetic	2	1	1	Negative Genetic, Negative Genetic
COG3	YER157W	Essential component of the conserved oligomeric Golgi complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PCF11	YDR228C	mRNA 3' end processing factor	genetic	2	1	1	Negative Genetic, Negative Genetic
SSB1	YDL229W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
YNG2	YHR090C	Subunit of NuA4, an essential histone acetyltransferase complex	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
SPT20	YOL148C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPS11B	YBR048W	Protein component of the small (40S) ribosomal subunit	genetic	2	1	1	Positive Genetic, Positive Genetic
PTP1	YDL230W	Phosphotyrosine-specific protein phosphatase	genetic	2	1	1	Positive Genetic, Positive Genetic
VAM7	YGL212W	Vacuolar SNARE protein	genetic	2	1	1	Negative Genetic, Negative Genetic
RIM8	YGL045W	Protein involved in proteolytic activation of Rim101p	genetic	2	1	1	Negative Genetic, Negative Genetic
VSB1	YGR125W	Vacuolar membrane protein required for uptake and storage of arginine	genetic	2	1	1	Positive Genetic, Positive Genetic
SDH1	YKL148C	Flavoprotein subunit of succinate dehydrogenase	genetic	2	1	1	Negative Genetic, Negative Genetic
RAD27	YKL113C	5' to 3' exonuclease, 5' flap endonuclease	genetic	2	1	1	Negative Genetic, Negative Genetic
SOV1	YMR066W	Mitochondrial protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SGT1	YOR057W	Cochaperone protein	genetic	2	1	1	Positive Genetic, Positive Genetic
SNU23	YDL098C	Component of the U4/U6.U5 snRNP complex	genetic	2	1	1	Negative Genetic, Negative Genetic
TFB1	YDR311W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC20	YDR498C	Membrane glycoprotein v-SNARE	genetic	2	1	1	Negative Genetic, Negative Genetic
RPN11	YFR004W	Metalloprotease subunit of 19S regulatory particle	genetic	2	1	1	Negative Genetic, Negative Genetic
RPT6	YGL048C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC15	YGL233W	Essential 113 kDa subunit of the exocyst complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PRP31	YGR091W	Splicing factor	genetic	2	1	1	Negative Genetic, Negative Genetic
RHO3	YIL118W	Non-essential small GTPase of the Rho/Rac family of Ras-like proteins	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC10	YLR166C	Essential 100kDa subunit of the exocyst complex	genetic	2	1	1	Negative Genetic, Negative Genetic
RSE1	YML049C	Protein involved in pre-mRNA splicing	genetic	2	1	1	Negative Genetic, Negative Genetic
VTI1	YMR197C	Protein involved in cis-Golgi membrane traffic	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC16	YPL085W	COPII vesicle coat protein required for ER transport vesicle budding	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC8	YPR055W	Essential 121 kDa subunit of the exocyst complex	genetic	2	1	1	Negative Genetic, Negative Genetic
RDS3	YPR094W	Component of the SF3b subcomplex of the U2 snRNP	genetic	2	1	1	Negative Genetic, Negative Genetic
SGV1	YPR161C	Cyclin (Bur2p)-dependent protein kinase	genetic	2	1	1	Negative Genetic, Negative Genetic
PTK2	YJR059W	Serine/threonine protein kinase	genetic	2	1	1	Negative Genetic, Negative Genetic
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NGG1	YDR176W	Subunit of chromatin modifying histone acetyltransferase complexes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NEW1	YPL226W	Translation termination and ribosome biogenesis factor	genetic	2	1	1	Negative Genetic, Negative Genetic
BET5	YML077W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	2	1	1	Negative Genetic, Negative Genetic
DNM1	YLL001W	Dynamin-related GTPase involved in mitochondrial organization	genetic	2	1	1	Positive Genetic, Positive Genetic
ACS2	YLR153C	Acetyl-coA synthetase isoform	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
GPP2	YER062C	DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis	genetic	2	1	1	Negative Genetic, Negative Genetic
HOM6	YJR139C	Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase)	genetic	2	1	1	Negative Genetic, Negative Genetic
ECM33	YBR078W	GPI-anchored protein involved in efficient glucose uptake	genetic	2	1	1	Negative Genetic, Negative Genetic
MDJ1	YFL016C	Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
EXO70	YJL085W	Subunit of the exocyst complex	genetic	2	1	1	Negative Genetic, Negative Genetic
APM4	YOL062C	Cargo-binding mu subunit of AP-2	genetic	2	1	1	Negative Genetic, Negative Genetic
NUR1	YDL089W	Protein involved in regulation of mitotic exit	genetic	2	1	1	Negative Genetic, Negative Genetic
HOP1	YIL072W	Meiosis-specific protein required for chromosome synapsis	genetic	2	1	1	Negative Genetic, Negative Genetic
OST2	YOR103C	Epsilon subunit of the oligosaccharyltransferase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
CHS5	YLR330W	Component of the exomer complex	genetic	2	1	1	Negative Genetic, Negative Genetic
BCS1	YDR375C	Protein translocase and chaperone required for Complex III assembly	genetic	2	1	1	Positive Genetic, Positive Genetic
ATP18	YML081C-A	Subunit of the mitochondrial F1F0 ATP synthase	genetic	2	1	1	Positive Genetic, Positive Genetic
ETR1	YBR026C	2-enoyl thioester reductase	genetic	2	1	1	Positive Genetic, Positive Genetic
MGR1	YCL044C	Subunit of the mitochondrial (mt) i-AAA protease supercomplex	genetic	2	1	1	Positive Genetic, Positive Genetic
BST1	YFL025C	GPI inositol deacylase of the endoplasmic reticulum (ER)	genetic	2	1	1	Negative Genetic, Negative Genetic
MPS3	YJL019W	Nuclear envelope protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DFG16	YOR030W	Probable multiple transmembrane protein	genetic	2	1	1	Negative Genetic, Negative Genetic
FRT1	YOR324C	Tail-anchored ER membrane protein of unknown function	genetic	2	1	1	Negative Genetic, Negative Genetic
COX12	YLR038C	Subunit VIb of cytochrome c oxidase	genetic	2	1	1	Negative Genetic, Negative Genetic
LIP2	YLR239C	Lipoyl ligase	genetic	2	1	1	Positive Genetic, Positive Genetic
FKH2	YNL068C	Forkhead family transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
LEU3	YLR451W	Zinc-knuckle transcription factor, repressor and activator	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CAD1	YDR423C	AP-1-like basic leucine zipper (bZIP) transcriptional activator	regulation	1	1	1	DNA to cDNA expression microarray evidence
ALD3	YMR169C	Cytoplasmic aldehyde dehydrogenase	regulation	1	1	1	northern blot evidence
CTT1	YGR088W	Cytosolic catalase T	regulation	1	1	1	northern blot evidence
AME1	YBR211C	Essential kinetochore protein associated with microtubules and SPBs	genetic	1	1	1	Positive Genetic
DED81	YHR019C	Cytosolic asparaginyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
CKB2	YOR039W	Beta' regulatory subunit of casein kinase 2 (CK2)	genetic	1	1	1	Positive Genetic
MMS21	YEL019C	Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
NSE4	YDL105W	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
ARC1	YGL105W	Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases	genetic	1	1	1	Negative Genetic
BMH1	YER177W	14-3-3 protein, major isoform	genetic	1	1	1	Positive Genetic
NOP56	YLR197W	Essential evolutionarily-conserved nucleolar protein	genetic	1	1	1	Positive Genetic
AIR2	YDL175C	RNA-binding subunit of the TRAMP nuclear RNA surveillance complex	genetic	1	1	1	Negative Genetic
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	genetic	1	1	1	Negative Genetic
PAB1	YER165W	Poly(A) binding protein	genetic	1	1	1	Negative Genetic
LRP1	YHR081W	Nuclear exosome-associated nucleic acid binding protein	genetic	1	1	1	Positive Genetic
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
ARX1	YDR101C	Nuclear export factor for the ribosomal pre-60S subunit	genetic	1	1	1	Negative Genetic
NOP12	YOL041C	Nucleolar protein involved in pre-25S rRNA processing	genetic	1	1	1	Positive Genetic
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	1	1	1	Negative Genetic
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
NAM7	YMR080C	ATP-dependent RNA helicase of the SFI superfamily	genetic	1	1	1	Negative Genetic
ADE4	YMR300C	Phosphoribosylpyrophosphate amidotransferase (PRPPAT)	genetic	1	1	1	Negative Genetic
ARC15	YIL062C	Subunit of the ARP2/3 complex	genetic	1	1	1	Negative Genetic
ARC35	YNR035C	Subunit of the ARP2/3 complex	genetic	1	1	1	Negative Genetic
ARD1	YHR013C	Subunit of protein N-terminal acetyltransferase NatA	genetic	1	1	1	Synthetic Growth Defect
BET3	YKR068C	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Positive Genetic
BUD31	YCR063W	Component of the SF3b subcomplex of the U2 snRNP	genetic	1	1	1	Negative Genetic
CEG1	YGL130W	Guanylyltransferase involved in mRNA 5' capping	genetic	1	1	1	Negative Genetic
CKS1	YBR135W	Cyclin-dependent protein kinase regulatory subunit and adaptor	genetic	1	1	1	Negative Genetic
CLP1	YOR250C	Component of the cleavage and polyadenylation factor I (CF I)	genetic	1	1	1	Negative Genetic
CYR1	YJL005W	Adenylate cyclase	genetic	1	1	1	Positive Genetic
DNA2	YHR164C	ATP-dependent 5'-flap endonuclease and DNA helicase	genetic	1	1	1	Synthetic Lethality
CDC23	YHR166C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
FIP1	YJR093C	Subunit of cleavage polyadenylation factor (CPF)	genetic	1	1	1	Negative Genetic
CCT4	YDL143W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
GLO3	YER122C	ADP-ribosylation factor GTPase activating protein (ARF GAP)	genetic	1	1	1	Negative Genetic
DYN1	YKR054C	Cytoplasmic heavy chain dynein	genetic	1	1	1	Positive Genetic
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
HRP1	YOL123W	Subunit of cleavage factor I	genetic	1	1	1	Negative Genetic
KIN3	YAR018C	Nonessential serine/threonine protein kinase	genetic	1	1	1	Positive Genetic
HSL1	YKL101W	Nim1p-related protein kinase	genetic	1	1	1	Negative Genetic
KRR1	YCL059C	Nucleolar protein required for rRNA synthesis and ribosomal assembly	genetic	1	1	1	Positive Genetic
ENO2	YHR174W	Enolase II, a phosphopyruvate hydratase	genetic	1	1	1	Positive Genetic
MDM10	YAL010C	Subunit of both the ERMES and the SAM complex	genetic	1	1	1	Negative Genetic
MLH1	YMR167W	Protein required for mismatch repair in mitosis and meiosis	genetic	1	1	1	Positive Genetic
MOT1	YPL082C	Essential protein involved in regulation of transcription	physical	1	1	1	Affinity Capture-MS
MRP1	YDR347W	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
IMG1	YCR046C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
IMG2	YCR071C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
MRPL1	YDR116C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
MRPL39	YML009C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
FYV4	YHR059W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MGM101	YJR144W	Protein with a role in mitochondrial DNA recombinational repair	genetic	1	1	1	Negative Genetic
MTR10	YOR160W	Nuclear import receptor	genetic	1	1	1	Positive Genetic
GIN4	YDR507C	Protein kinase involved in bud growth and assembly of the septin ring	genetic	1	1	1	Dosage Growth Defect
IES1	YFL013C	Subunit of the INO80 chromatin remodeling complex	genetic	1	1	1	Negative Genetic
NUP159	YIL115C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Positive Genetic
ORC2	YBR060C	Subunit of the origin recognition complex (ORC)	genetic	1	1	1	Negative Genetic
PAC10	YGR078C	Part of the heteromeric co-chaperone GimC/prefoldin complex	genetic	1	1	1	Negative Genetic
DAM1	YGR113W	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
MIR1	YJR077C	Mitochondrial phosphate carrier	genetic	1	1	1	Negative Genetic
MRPL6	YHR147C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
PGD1	YGL025C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
IWR1	YDL115C	RNA polymerase II transport factor, conserved from yeast to humans	genetic	1	1	1	Negative Genetic
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	physical	1	1	1	Affinity Capture-MS
UME1	YPL139C	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	1	1	1	Negative Genetic
UME6	YDR207C	Rpd3L histone deacetylase complex subunit	physical	1	1	1	Affinity Capture-MS
UME6	YDR207C	Rpd3L histone deacetylase complex subunit	genetic	1	1	1	Negative Genetic
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	physical	1	1	1	Affinity Capture-MS
YCK2	YNL154C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	physical	1	1	1	Biochemical Activity
SPC25	YER018C	Component of the kinetochore-associated Ndc80 complex	physical	1	1	1	Two-hybrid
SRO9	YCL037C	Cytoplasmic RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
TAF13	YML098W	TFIID subunit (19 kDa)	genetic	1	1	1	Negative Genetic
SGO1	YOR073W	Component of the spindle checkpoint	genetic	1	1	1	Negative Genetic
SRB2	YHR041C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
RIM1	YCR028C-A	ssDNA-binding protein essential for mitochondrial genome maintenance	genetic	1	1	1	Negative Genetic
REI1	YBR267W	Cytoplasmic pre-60S factor	genetic	1	1	1	Phenotypic Suppression
RAD3	YER171W	5' to 3' DNA helicase	genetic	1	1	1	Negative Genetic
RPB3	YIL021W	RNA polymerase II third largest subunit B44	genetic	1	1	1	Negative Genetic
VPH2	YKL119C	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Phenotypic Suppression
SET5	YHR207C	Methyltransferase involved in methylation of histone H4 Lys5, -8, -12	genetic	1	1	1	Phenotypic Suppression
SND3	YBR106W	Involved in SRP-independent protein targeting to the ER	genetic	1	1	1	Phenotypic Suppression
SAS4	YDR181C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p)	genetic	1	1	1	Negative Genetic
RAD50	YNL250W	Subunit of MRX complex with Mre11p and Xrs2p	genetic	1	1	1	Negative Genetic
VRP1	YLR337C	Verprolin, proline-rich actin-associated protein	genetic	1	1	1	Negative Genetic
SAP185	YJL098W	Protein that forms a complex with the Sit4p protein phosphatase	genetic	1	1	1	Negative Genetic
PZF1	YPR186C	Transcription factor IIIA (TFIIIA)	genetic	1	1	1	Negative Genetic
SAS2	YMR127C	Histone acetyltransferase (HAT) catalytic subunit of the SAS complex	genetic	1	1	1	Negative Genetic
VPS64	YDR200C	Protein required for cytoplasm to vacuole targeting of proteins	genetic	1	1	1	Positive Genetic
UBA3	YPR066W	Protein that activates Rub1p (NEDD8) before neddylation	genetic	1	1	1	Positive Genetic
RTS1	YOR014W	B-type regulatory subunit of protein phosphatase 2A (PP2A)	genetic	1	1	1	Positive Genetic
POP7	YBR167C	Subunit of RNase MRP, nuclear RNase P and telomerase	genetic	1	1	1	Negative Genetic
SYC1	YOR179C	Subunit of the APT subcomplex of cleavage and polyadenylation factor	genetic	1	1	1	Negative Genetic
RLI1	YDR091C	Essential Fe-S protein	genetic	1	1	1	Positive Genetic
YCR016W	YCR016W	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
RSA3	YLR221C	Protein with a likely role in ribosomal maturation	genetic	1	1	1	Positive Genetic
UTP11	YKL099C	Subunit of U3-containing Small Subunit (SSU) processome complex	genetic	1	1	1	Positive Genetic
TGS1	YPL157W	Trimethyl guanosine synthase, conserved nucleolar methyl transferase	genetic	1	1	1	Positive Genetic
RRP4	YHR069C	Exosome non-catalytic core component	genetic	1	1	1	Positive Genetic
SSF1	YHR066W	Constituent of 66S pre-ribosomal particles	genetic	1	1	1	Positive Genetic
RIP1	YEL024W	Ubiquinol-cytochrome-c reductase	genetic	1	1	1	Negative Genetic
UTP22	YGR090W	Component of the small-subunit processome	genetic	1	1	1	Negative Genetic
STU2	YLR045C	Microtubule polymerase of the XMAP215/Dis1 family	genetic	1	1	1	Negative Genetic
YHC1	YLR298C	Component of the U1 snRNP complex required for pre-mRNA splicing	genetic	1	1	1	Positive Genetic
YBR053C	YBR053C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
TEF2	YBR118W	Translational elongation factor EF-1 alpha	genetic	1	1	1	Negative Genetic
SHG1	YBR258C	Subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
SHM1	YBR263W	Mitochondrial serine hydroxymethyltransferase	genetic	1	1	1	Negative Genetic
TVS1	YCR061W	Protein of unknown function	genetic	1	1	1	Negative Genetic
RPP1A	YDL081C	Ribosomal stalk protein P1 alpha	genetic	1	1	1	Negative Genetic
PPH3	YDR075W	Catalytic subunit of protein phosphatase PP4 complex	genetic	1	1	1	Negative Genetic
RPS24A	YER074W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
VFA1	YER128W	Protein that interacts with Vps4p and has a role in vacuolar sorting	genetic	1	1	1	Negative Genetic
RMD8	YFR048W	Cytosolic protein required for sporulation	genetic	1	1	1	Negative Genetic
YGL235W	YGL235W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SNF4	YGL115W	Activating gamma subunit of the AMP-activated Snf1p kinase complex	genetic	1	1	1	Negative Genetic
YGK1	YGL101W	5'-deoxynucleotidase	genetic	1	1	1	Positive Genetic
YGR122W	YGR122W	Protein that may be involved in pH regulation	genetic	1	1	1	Negative Genetic
YHR112C	YHR112C	Protein of unknown function	genetic	1	1	1	Positive Genetic
SDL1	YIL167W	Blocked reading frame otherwise encoding L-serine dehydratase	genetic	1	1	1	Negative Genetic
XBP1	YIL101C	Transcriptional repressor	genetic	1	1	1	Negative Genetic
RPE1	YJL121C	D-ribulose-5-phosphate 3-epimerase	genetic	1	1	1	Negative Genetic
YKL162C	YKL162C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SRN2	YLR119W	Component of the ESCRT-I complex	genetic	1	1	1	Negative Genetic
YNR014W	YNR014W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SDH5	YOL071W	Protein required for flavinylation of Sdh1p	genetic	1	1	1	Negative Genetic
RDL2	YOR286W	Protein with rhodanese activity	genetic	1	1	1	Negative Genetic
VPS30	YPL120W	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II	genetic	1	1	1	Negative Genetic
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	genetic	1	1	1	Negative Genetic
SDD4	YPR022C	Putative transcription factor, as suggested by computational analysis	genetic	1	1	1	Negative Genetic
TKL1	YPR074C	Transketolase	genetic	1	1	1	Negative Genetic
PUB1	YNL016W	Poly (A)+ RNA-binding protein	genetic	1	1	1	Negative Genetic
RSF2	YJR127C	Zinc-finger protein	genetic	1	1	1	Negative Genetic
ZAP1	YJL056C	Zinc-regulated transcription factor	genetic	1	1	1	Positive Genetic
PUL4	YNR063W	Putative zinc-cluster transcription factor	genetic	1	1	1	Negative Genetic
SRD1	YCR018C	Protein involved in the processing of pre-rRNA to mature rRNA	genetic	1	1	1	Negative Genetic
RPI1	YIL119C	Transcription factor, allelic differences between S288C and Sigma1278b	genetic	1	1	1	Negative Genetic
RPA34	YJL148W	RNA polymerase I subunit A34.5	genetic	1	1	1	Negative Genetic
TDA9	YML081W	Transcription factor that regulates acetate production	genetic	1	1	1	Negative Genetic
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	genetic	1	1	1	Negative Genetic
SIW14	YNL032W	Inositol phosphatase involved in inositol pyrophosphate metabolism	genetic	1	1	1	Negative Genetic
YVH1	YIR026C	Dual specificity protein phosphatase	genetic	1	1	1	Negative Genetic
TIM8	YJR135W-A	Mitochondrial intermembrane space protein	genetic	1	1	1	Negative Genetic
YTA12	YMR089C	Mitochondrial inner membrane m-AAA protease component	genetic	1	1	1	Negative Genetic
PPA2	YMR267W	Mitochondrial inorganic pyrophosphatase	genetic	1	1	1	Negative Genetic
RUD3	YOR216C	Golgi matrix protein	genetic	1	1	1	Negative Genetic
SFL1	YOR140W	Transcriptional repressor and activator	genetic	1	1	1	Phenotypic Suppression
RPO21	YDL140C	RNA polymerase II largest subunit B220	genetic	1	1	1	Synthetic Growth Defect
RAD51	YER095W	Strand exchange protein	genetic	1	1	1	Synthetic Growth Defect
YCG1	YDR325W	Subunit of the condensin complex	genetic	1	1	1	Positive Genetic
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	genetic	1	1	1	Positive Genetic
SCC4	YER147C	Subunit of cohesin loading factor (Scc2p-Scc4p)	genetic	1	1	1	Positive Genetic
SRM1	YGL097W	Nucleotide exchange factor for Gsp1p	genetic	1	1	1	Positive Genetic
UFD1	YGR048W	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	1	1	1	Positive Genetic
SMC4	YLR086W	Subunit of the condensin complex	genetic	1	1	1	Positive Genetic
TAP42	YMR028W	Essential protein involved in the TOR signaling pathway	genetic	1	1	1	Positive Genetic
RPA190	YOR341W	RNA polymerase I largest subunit A190	genetic	1	1	1	Positive Genetic
PIN4	YBL051C	Protein involved in G2/M phase progression and response to DNA damage	genetic	1	1	1	Positive Genetic
VPS54	YDR027C	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Positive Genetic
SOM1	YEL059C-A	Subunit of the mitochondrial inner membrane peptidase (IMP)	genetic	1	1	1	Positive Genetic
SEH1	YGL100W	Subunit of the Nup84 nuclear pore and SEACAT subcomplexes	genetic	1	1	1	Positive Genetic
YJL070C	YJL070C	Putative metallo-dependent hydrolase superfamily protein	genetic	1	1	1	Positive Genetic
PTC1	YDL006W	Type 2C protein phosphatase (PP2C)	genetic	1	1	1	Positive Genetic
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	1	1	1	Positive Genetic
RPL22A	YLR061W	Ribosomal 60S subunit protein L22A	genetic	1	1	1	Positive Genetic
RPL20B	YOR312C	Ribosomal 60S subunit protein L20B	genetic	1	1	1	Positive Genetic
SNT309	YPR101W	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Positive Genetic
STU1	YBL034C	Microtubule plus-end-tracking non-motor protein	genetic	1	1	1	Negative Genetic
REB1	YBR049C	RNA polymerase I enhancer binding protein	genetic	1	1	1	Negative Genetic
PRP6	YBR055C	Splicing factor	genetic	1	1	1	Negative Genetic
POP4	YBR257W	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
PRP11	YDL043C	Subunit of the SF3a splicing factor complex	genetic	1	1	1	Negative Genetic
SUB2	YDL084W	Component of the TREX complex required for nuclear mRNA export	genetic	1	1	1	Negative Genetic
RRP42	YDL111C	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
SLU7	YDR088C	RNA splicing factor	genetic	1	1	1	Negative Genetic
SEC1	YDR164C	Sm-like protein involved in docking and fusion of exocytic vesicles	genetic	1	1	1	Negative Genetic
RPT3	YDR394W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	1	1	1	Negative Genetic
TRS31	YDR472W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
WBP1	YEL002C	Beta subunit of the oligosaccharyl transferase glycoprotein complex	genetic	1	1	1	Negative Genetic
TUB2	YFL037W	Beta-tubulin	genetic	1	1	1	Negative Genetic
RSC8	YFR037C	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
RPS2	YGL123W	Protein component of the small (40S) subunit	genetic	1	1	1	Negative Genetic
TIP20	YGL145W	Peripheral membrane protein required for COPI vesicle fusion to the ER	genetic	1	1	1	Negative Genetic
TFG2	YGR005C	TFIIF (Transcription Factor II) middle subunit	genetic	1	1	1	Negative Genetic
VHT1	YGR065C	High-affinity plasma membrane H+-biotin (vitamin H) symporter	genetic	1	1	1	Negative Genetic
PTI1	YGR156W	Essential component of CPF (cleavage and polyadenylation factor)	genetic	1	1	1	Negative Genetic
YIP1	YGR172C	Integral membrane protein	genetic	1	1	1	Negative Genetic
TAO3	YIL129C	Component of the RAM signaling network	genetic	1	1	1	Negative Genetic
SLN1	YIL147C	Transmembrane histidine phosphotransfer kinase and osmosensor	genetic	1	1	1	Negative Genetic
TIM54	YJL054W	Component of the mitochondrial TIM22 complex	genetic	1	1	1	Negative Genetic
UTP18	YJL069C	Small-subunit processome protein involved in pre-18S rRNA maturation	genetic	1	1	1	Negative Genetic
PHS1	YJL097W	Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane	genetic	1	1	1	Negative Genetic
RRP14	YKL082C	Essential protein, constituent of 66S pre-ribosomal particles	genetic	1	1	1	Negative Genetic
RPT1	YKL145W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	1	1	1	Negative Genetic
SNU114	YKL173W	GTPase component of U5 snRNP involved in mRNA splicing via spliceosome	genetic	1	1	1	Negative Genetic
YKT6	YKL196C	Vesicle membrane protein (v-SNARE) with acyltransferase activity	genetic	1	1	1	Negative Genetic
RLP24	YLR009W	Essential protein required for ribosomal large subunit biogenesis	genetic	1	1	1	Negative Genetic
SMD2	YLR275W	Core Sm protein Sm D2	genetic	1	1	1	Negative Genetic
PRP39	YML046W	U1 snRNP protein involved in splicing	genetic	1	1	1	Negative Genetic
RNA14	YMR061W	Component of the cleavage and polyadenylation factor I (CF I)	genetic	1	1	1	Negative Genetic
TIF34	YMR146C	eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3)	genetic	1	1	1	Negative Genetic
SWP1	YMR149W	Delta subunit of the oligosaccharyl transferase glycoprotein complex	genetic	1	1	1	Negative Genetic
RRN9	YMR270C	Protein involved in promoting high level transcription of rDNA	genetic	1	1	1	Negative Genetic
RPS15	YOL040C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
RPL3	YOR063W	Ribosomal 60S subunit protein L3	genetic	1	1	1	Negative Genetic
RPB10	YOR210W	RNA polymerase subunit ABC10-beta	genetic	1	1	1	Negative Genetic
SRP68	YPL243W	Core component of the signal recognition particle (SRP) complex	genetic	1	1	1	Negative Genetic
SEC23	YPR181C	GTPase-activating protein, stimulates the GTPase activity of Sar1p	genetic	1	1	1	Negative Genetic
SMX3	YPR182W	Core Sm protein Sm F	genetic	1	1	1	Negative Genetic
SEC18	YBR080C	AAA ATPase and SNARE disassembly chaperone	genetic	1	1	1	Negative Genetic
PRP5	YBR237W	RNA helicase in the DEAD-box family	genetic	1	1	1	Negative Genetic
PRP9	YDL030W	Subunit of the SF3a splicing factor complex	genetic	1	1	1	Negative Genetic
RPN6	YDL097C	Essential, non-ATPase regulatory subunit of the 26S proteasome lid	genetic	1	1	1	Negative Genetic
SSS1	YDR086C	Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p)	genetic	1	1	1	Negative Genetic
RPB7	YDR404C	RNA polymerase II subunit B16	genetic	1	1	1	Negative Genetic
SEC4	YFL005W	Rab family GTPase	genetic	1	1	1	Negative Genetic
SAD1	YFR005C	Conserved zinc-finger domain protein involved in pre-mRNA splicing	genetic	1	1	1	Negative Genetic
STT3	YGL022W	Catalytic subunit of the oligosaccharyltransferase complex of the ER l	genetic	1	1	1	Negative Genetic
PRP21	YJL203W	Subunit of the SF3a splicing factor complex	genetic	1	1	1	Negative Genetic
SMP3	YOR149C	Alpha 1,2-mannosyltransferase	genetic	1	1	1	Negative Genetic
RKM3	YBR030W	Ribosomal lysine methyltransferase	genetic	1	1	1	Negative Genetic
SHE3	YBR130C	Protein adaptor between Myo4p and the She2p-mRNA complex	genetic	1	1	1	Negative Genetic
RAD18	YCR066W	E3 ubiquitin ligase	genetic	1	1	1	Negative Genetic
RMD1	YDL001W	Cytoplasmic protein required for sporulation	genetic	1	1	1	Negative Genetic
YDR003W-A	YDR003W-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RSM28	YDR494W	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
URC2	YDR520C	Putative Zn(II)2Cys6 motif containing transcription factor	genetic	1	1	1	Negative Genetic
YND1	YER005W	Apyrase with wide substrate specificity	genetic	1	1	1	Negative Genetic
YER010C	YER010C	Bifunctional HMG aldolase/oxaloacetate decarboxylase	genetic	1	1	1	Negative Genetic
STF2	YGR008C	Protein involved in resistance to desiccation stress	genetic	1	1	1	Negative Genetic
YGR017W	YGR017W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SNG1	YGR197C	Protein involved in resistance to nitrosoguanidine and 6-azauracil	genetic	1	1	1	Negative Genetic
RIM4	YHL024W	Putative RNA-binding protein	genetic	1	1	1	Negative Genetic
YIL014C-A	YIL014C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
PRM2	YIL037C	Pheromone-regulated protein	genetic	1	1	1	Negative Genetic
YJL107C	YJL107C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RAD7	YJR052W	Nucleotide excision repair (NER) protein	genetic	1	1	1	Negative Genetic
YJR056C	YJR056C	Protein of unknown function	genetic	1	1	1	Negative Genetic
RSM22	YKL155C	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
ZRT3	YKL175W	Vacuolar membrane zinc transporter	genetic	1	1	1	Negative Genetic
SND2	YLR065C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	1	1	1	Negative Genetic
SWC7	YLR385C	Protein of unknown function	genetic	1	1	1	Negative Genetic
YMR295C	YMR295C	Protein of unknown function that associates with ribosomes	genetic	1	1	1	Negative Genetic
STP4	YDL048C	Protein containing a Kruppel-type zinc-finger domain	genetic	1	1	1	Negative Genetic
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	genetic	1	1	1	Negative Genetic
SRF1	YDL133W	Regulator of phospholipase D (Spo14p)	genetic	1	1	1	Negative Genetic
XRS2	YDR369C	FHA domain-containing component of the Mre11 complex	genetic	1	1	1	Negative Genetic
RGA2	YDR379W	GTPase-activating protein for polarity-establishment protein Cdc42p	genetic	1	1	1	Negative Genetic
RAD4	YER162C	Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2	genetic	1	1	1	Negative Genetic
YJR084W	YJR084W	Protein that forms a complex with Thp3p	genetic	1	1	1	Negative Genetic
TSR2	YLR435W	Protein with a potential role in pre-rRNA processing	genetic	1	1	1	Negative Genetic
UBX4	YMR067C	UBX domain-containing protein that interacts with Cdc48p	genetic	1	1	1	Negative Genetic
TOM6	YOR045W	Component of the TOM (translocase of outer membrane) complex	genetic	1	1	1	Negative Genetic
QCR2	YPR191W	Subunit 2 of ubiquinol cytochrome-c reductase (Complex III)	genetic	1	1	1	Negative Genetic
YSP3	YOR003W	Putative precursor of the subtilisin-like protease III	genetic	1	1	1	Negative Genetic
YPL039W	YPL039W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
THP3	YPR045C	Protein that may have a role in transcription elongation	genetic	1	1	1	Negative Genetic
SYT1	YPR095C	Guanine nucleotide exchange factor (GEF) for Arf proteins	genetic	1	1	1	Negative Genetic
PSY4	YBL046W	Regulatory subunit of protein phosphatase PP4	genetic	1	1	1	Positive Genetic
RTK1	YDL025C	Putative protein kinase, potentially phosphorylated by Cdc28p	genetic	1	1	1	Negative Genetic
PPT1	YGR123C	Protein serine/threonine phosphatase	genetic	1	1	1	Positive Genetic
TDH2	YJR009C	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2	genetic	1	1	1	Positive Genetic
TAH18	YPR048W	Conserved NAPDH-dependent diflavin reductase	genetic	1	1	1	Positive Genetic
RPC40	YPR110C	RNA polymerase subunit AC40	genetic	1	1	1	Positive Genetic
YOR1	YGR281W	Plasma membrane ATP-binding cassette (ABC) transporter	genetic	1	1	1	Positive Genetic
YPT31	YER031C	Rab family GTPase	genetic	1	1	1	Negative Genetic
YIA6	YIL006W	Mitochondrial NAD+ transporter	genetic	1	1	1	Negative Genetic
SPE2	YOL052C	S-adenosylmethionine decarboxylase	genetic	1	1	1	Positive Genetic
SKM1	YOL113W	Member of the PAK family of serine/threonine protein kinases	genetic	1	1	1	Negative Genetic
PRK1	YIL095W	Ser/Thr protein kinase	genetic	1	1	1	Positive Genetic
SPE1	YKL184W	Ornithine decarboxylase	genetic	1	1	1	Positive Genetic
TAT1	YBR069C	Amino acid transporter for valine, leucine, isoleucine, and tyrosine	genetic	1	1	1	Positive Genetic
RAD52	YML032C	Protein involved in homologous recombination	genetic	1	1	1	Negative Genetic
YMR1	YJR110W	Phosphatidylinositol 3-phosphate (PI3P) phosphatase	genetic	1	1	1	Positive Genetic
YMR317W	YMR317W	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
YMR226C	YMR226C	NADP(+)-dependent serine dehydrogenase and carbonyl reductase	genetic	1	1	1	Positive Genetic
VPS53	YJL029C	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Positive Genetic
UBP12	YJL197W	Ubiquitin-specific protease	genetic	1	1	1	Negative Genetic
SCH9	YHR205W	AGC family protein kinase	genetic	1	1	1	Negative Genetic
SOD1	YJR104C	Cytosolic copper-zinc superoxide dismutase	genetic	1	1	1	Positive Genetic
RAD5	YLR032W	DNA helicase/Ubiquitin ligase	genetic	1	1	1	Negative Genetic
YPT1	YFL038C	Rab family GTPase	genetic	1	1	1	Negative Genetic
TUB4	YLR212C	Gamma-tubulin	genetic	1	1	1	Synthetic Rescue
YNG1	YOR064C	Subunit of the NuA3 histone acetyltransferase complex	genetic	1	1	1	Phenotypic Suppression
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	1	1	1	Positive Genetic
YPC1	YBR183W	Alkaline ceramidase	genetic	1	1	1	Negative Genetic
CTI6	YPL181W	Component of the Rpd3L histone deacetylase complex	genetic	1	1	1	Phenotypic Enhancement
CDC6	YJL194W	Essential ATP-binding protein required for DNA replication	genetic	1	1	1	Negative Genetic
NUM1	YDR150W	Protein required for nuclear migration	genetic	1	1	1	Positive Genetic
OPI1	YHL020C	Transcriptional regulator of a variety of genes	genetic	1	1	1	Negative Genetic
NUP120	YKL057C	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
NUP84	YDL116W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
NUP85	YJR042W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
CSE1	YGL238W	Nuclear envelope protein that acts as a recycling factor	genetic	1	1	1	Negative Genetic
ABF2	YMR072W	Mitochondrial DNA-binding protein	genetic	1	1	1	Negative Genetic
HRK1	YOR267C	Protein kinase	genetic	1	1	1	Negative Genetic
HEM13	YDR044W	Coproporphyrinogen III oxidase	genetic	1	1	1	Negative Genetic
ATG9	YDL149W	Transmembrane protein involved in forming Cvt and autophagic vesicles	genetic	1	1	1	Negative Genetic
ACE2	YLR131C	Transcription factor required for septum destruction after cytokinesis	genetic	1	1	1	Negative Genetic
CAB5	YDR196C	Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC)	genetic	1	1	1	Positive Genetic
NOB1	YOR056C	Protein involved in proteasomal and 40S ribosomal subunit biogenesis	genetic	1	1	1	Negative Genetic
HIR3	YJR140C	Subunit of the HIR complex	genetic	1	1	1	Negative Genetic
CDC53	YDL132W	Cullin	genetic	1	1	1	Positive Genetic
FYV10	YIL097W	Subunit of GID complex	genetic	1	1	1	Negative Genetic
CDC9	YDL164C	DNA ligase I found in nucleus and mitochondria	genetic	1	1	1	Positive Genetic
COF1	YLL050C	Cofilin, involved in pH-dependent actin filament depolarization	genetic	1	1	1	Negative Genetic
HEF3	YNL014W	Translational elongation factor EF-3	genetic	1	1	1	Positive Genetic
ERG10	YPL028W	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase)	genetic	1	1	1	Negative Genetic
MRS6	YOR370C	Rab escort protein	genetic	1	1	1	Negative Genetic
DOP1	YDR141C	Protein involved in vesicular transport at trans-Golgi network (TGN)	genetic	1	1	1	Negative Genetic
DUG2	YBR281C	Component of glutamine amidotransferase (GATase II)	genetic	1	1	1	Negative Genetic
KNS1	YLL019C	Protein kinase involved in negative regulation of PolIII transcription	genetic	1	1	1	Positive Genetic
ELM1	YKL048C	Serine/threonine protein kinase	genetic	1	1	1	Positive Genetic
MSI1	YBR195C	Subunit of chromatin assembly factor I (CAF-1)	genetic	1	1	1	Negative Genetic
HRT3	YLR097C	Putative SCF-ubiquitin ligase F-box protein	genetic	1	1	1	Negative Genetic
FHL1	YPR104C	Regulator of ribosomal protein (RP) transcription	genetic	1	1	1	Negative Genetic
FAR10	YLR238W	Protein involved in recovery from arrest in response to pheromone	genetic	1	1	1	Positive Genetic
ADH4	YGL256W	Alcohol dehydrogenase isoenzyme type IV	genetic	1	1	1	Negative Genetic
FRS2	YFL022C	Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
CTF13	YMR094W	Subunit of the CBF3 complex	genetic	1	1	1	Positive Genetic
BCK2	YER167W	Serine/threonine-rich protein involved in PKC1 signaling pathway	genetic	1	1	1	Negative Genetic
ICP55	YER078C	Mitochondrial aminopeptidase	genetic	1	1	1	Negative Genetic
CIK1	YMR198W	Kinesin-associated protein	genetic	1	1	1	Negative Genetic
MAP2	YBL091C	Methionine aminopeptidase	genetic	1	1	1	Negative Genetic
AHC1	YOR023C	Subunit of the Ada histone acetyltransferase complex	genetic	1	1	1	Negative Genetic
PAP2	YOL115W	Non-canonical poly(A) polymerase	genetic	1	1	1	Negative Genetic
MCK1	YNL307C	Dual-specificity ser/thr and tyrosine protein kinase	genetic	1	1	1	Negative Genetic
CPR3	YML078W	Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	1	1	1	Positive Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	1	1	1	Negative Genetic
MSG5	YNL053W	Dual-specificity protein phosphatase	genetic	1	1	1	Negative Genetic
FUS3	YBL016W	Mitogen-activated serine/threonine protein kinase involved in mating	genetic	1	1	1	Positive Genetic
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	genetic	1	1	1	Negative Genetic
GCR2	YNL199C	Transcriptional activator of genes involved in glycolysis	genetic	1	1	1	Negative Genetic
CYS3	YAL012W	Cystathionine gamma-lyase	genetic	1	1	1	Negative Genetic
PEX15	YOL044W	Tail-anchored type II integral peroxisomal membrane protein	genetic	1	1	1	Negative Genetic
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	physical	1	1	1	Affinity Capture-MS
CRC1	YOR100C	Mitochondrial inner membrane carnitine transporter	genetic	1	1	1	Negative Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	1	1	1	Negative Genetic
DCK1	YLR422W	Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1	genetic	1	1	1	Positive Genetic
DUO1	YGL061C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Positive Genetic
HOF1	YMR032W	F-BAR protein that regulates actin cytoskeleton organization	genetic	1	1	1	Positive Genetic
CLN3	YAL040C	G1 cyclin involved in cell cycle progression	genetic	1	1	1	Negative Genetic
ECM19	YLR390W	Protein of unknown function	genetic	1	1	1	Negative Genetic
GTR1	YML121W	Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex	genetic	1	1	1	Positive Genetic
IPK1	YDR315C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase	genetic	1	1	1	Negative Genetic
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	physical	1	1	1	Biochemical Activity
MSN5	YDR335W	Karyopherin	genetic	1	1	1	Negative Genetic
HSP10	YOR020C	Mitochondrial matrix co-chaperonin	genetic	1	1	1	Negative Genetic
PDR8	YLR266C	Transcription factor	genetic	1	1	1	Negative Genetic
ART5	YGR068C	Protein proposed to regulate endocytosis of plasma membrane proteins	genetic	1	1	1	Negative Genetic
GPI16	YHR188C	Subunit of the glycosylphosphatidylinositol transamidase complex	genetic	1	1	1	Negative Genetic
ASK1	YKL052C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Positive Genetic
AIM4	YBR194W	Protein proposed to be associated with the nuclear pore complex	genetic	1	1	1	Negative Genetic
CDC26	YFR036W	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
DOC1	YGL240W	Processivity factor	genetic	1	1	1	Positive Genetic
CET1	YPL228W	RNA 5'-triphosphatase involved in mRNA 5' capping	genetic	1	1	1	Negative Genetic
NHP6A	YPR052C	High-mobility group (HMG) protein	genetic	1	1	1	Negative Genetic
DAL81	YIR023W	Positive regulator of genes in multiple nitrogen degradation pathways	genetic	1	1	1	Positive Genetic
IES2	YNL215W	Protein that associates with the INO80 chromatin remodeling complex	genetic	1	1	1	Negative Genetic
CPT1	YNL130C	Cholinephosphotransferase	genetic	1	1	1	Negative Genetic
CTK2	YJL006C	Beta subunit of C-terminal domain kinase I (CTDK-I)	genetic	1	1	1	Negative Genetic
DBP5	YOR046C	Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family	genetic	1	1	1	Negative Genetic
GIM4	YEL003W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Positive Genetic
MAD1	YGL086W	Coiled-coil protein involved in spindle-assembly checkpoint	genetic	1	1	1	Positive Genetic
MCM3	YEL032W	Protein involved in DNA replication	genetic	1	1	1	Positive Genetic
MPS1	YDL028C	Dual-specificity kinase	genetic	1	1	1	Positive Genetic
PET111	YMR257C	Mitochondrial translational activator specific for the COX2 mRNA	genetic	1	1	1	Negative Genetic
MGM1	YOR211C	Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p	genetic	1	1	1	Negative Genetic
BUD8	YLR353W	Protein involved in bud-site selection	genetic	1	1	1	Positive Genetic
FUS2	YMR232W	Cell fusion regulator	genetic	1	1	1	Negative Genetic
NUP170	YBL079W	Subunit of inner ring of nuclear pore complex (NPC)	genetic	1	1	1	Synthetic Growth Defect
BNR1	YIL159W	Formin	genetic	1	1	1	Positive Genetic
MUD2	YKL074C	Protein involved in early pre-mRNA splicing	genetic	1	1	1	Positive Genetic
FCP1	YMR277W	Carboxy-terminal domain (CTD) phosphatase	genetic	1	1	1	Negative Genetic
ARG80	YMR042W	Transcription factor involved in regulating arginine-responsive genes	genetic	1	1	1	Positive Genetic
AFI1	YOR129C	Arf3p polarization-specific docking factor	genetic	1	1	1	Negative Genetic
JEM1	YJL073W	DnaJ-like chaperone required for nuclear membrane fusion during mating	genetic	1	1	1	Negative Genetic
GAD1	YMR250W	Glutamate decarboxylase	genetic	1	1	1	Negative Genetic
HFA1	YMR207C	Mitochondrial acetyl-coenzyme A carboxylase	genetic	1	1	1	Negative Genetic
BCH1	YMR237W	Member of the ChAPs family (Chs5p-Arf1p-binding proteins)	genetic	1	1	1	Positive Genetic
MON1	YGL124C	Subunit of a heterodimeric guanine nucleotide exchange factor (GEF)	genetic	1	1	1	Negative Genetic
OTU1	YFL044C	Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p	genetic	1	1	1	Negative Genetic
PET309	YLR067C	Specific translational activator for the COX1 mRNA	genetic	1	1	1	Negative Genetic
DJP1	YIR004W	ER-associated chaperone involved in protein targeting	genetic	1	1	1	Negative Genetic
DPC29	YGR021W	Putative mitochondrial protein of unknown function	genetic	1	1	1	Negative Genetic
AZF1	YOR113W	Zinc-finger transcription factor	genetic	1	1	1	Positive Genetic
ATP10	YLR393W	Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase	genetic	1	1	1	Negative Genetic
ADY4	YLR227C	Structural component of the meiotic outer plaque	genetic	1	1	1	Negative Genetic
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	genetic	1	1	1	Positive Genetic
HHT2	YNL031C	Histone H3	genetic	1	1	1	Synthetic Growth Defect
PAM16	YJL104W	Subunit of the import motor (PAM complex)	genetic	1	1	1	Synthetic Growth Defect
HAC1	YFL031W	Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog)	genetic	1	1	1	Positive Genetic
GSM1	YJL103C	Putative zinc cluster protein of unknown function	genetic	1	1	1	Negative Genetic
KAP120	YPL125W	Karyopherin responsible for the nuclear import of Rpf1p	genetic	1	1	1	Positive Genetic
PAN3	YKL025C	Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex	genetic	1	1	1	Negative Genetic
ERV14	YGL054C	COPII-coated vesicle protein	genetic	1	1	1	Phenotypic Enhancement
GAB1	YLR459W	Subunit of the glycosylphosphatidylinositol transamidase complex	genetic	1	1	1	Negative Genetic
ORM2	YLR350W	Protein that mediates sphingolipid homeostasis	genetic	1	1	1	Negative Genetic
OKP1	YGR179C	Outer kinetochore protein required for accurate chromosome segregation	genetic	1	1	1	Negative Genetic
BTS1	YPL069C	Geranylgeranyl diphosphate synthase (GGPPS)	genetic	1	1	1	Positive Genetic
AGP2	YBR132C	Plasma membrane regulator of polyamine and carnitine transport	genetic	1	1	1	Positive Genetic
DIC1	YLR348C	Mitochondrial dicarboxylate carrier	genetic	1	1	1	Negative Genetic
ERG7	YHR072W	Lanosterol synthase	genetic	1	1	1	Negative Genetic
DAD4	YDR320C-A	Essential subunit of the Dam1 complex (aka DASH complex)	physical	1	1	1	Two-hybrid
DCC1	YCL016C	Subunit of a complex with Ctf8p and Ctf18p	genetic	1	1	1	Negative Genetic
HYR1	YIR037W	Glutathione peroxidase	genetic	1	1	1	Positive Genetic
MBA1	YBR185C	Membrane-associated mitochondrial ribosome receptor	genetic	1	1	1	Negative Genetic
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	1	1	1	Positive Genetic
KCS1	YDR017C	Inositol hexakisphosphate and inositol heptakisphosphate kinase	genetic	1	1	1	Negative Genetic
FCF2	YLR051C	Nucleolar protein involved in the early steps of 35S rRNA processing	genetic	1	1	1	Negative Genetic
MRPL17	YNL252C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
AIM22	YJL046W	Lipoate-protein ligase	genetic	1	1	1	Negative Genetic
JIP4	YDR475C	Protein of unknown function	genetic	1	1	1	Negative Genetic
PDC2	YDR081C	Transcription factor for thiamine-regulated genes	genetic	1	1	1	Negative Genetic
COQ11	YLR290C	Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes	genetic	1	1	1	Negative Genetic
ADE16	YLR028C	Enzyme of 'de novo' purine biosynthesis	genetic	1	1	1	Negative Genetic
BRL1	YHR036W	Essential nuclear envelope/ER integral membrane protein	genetic	1	1	1	Negative Genetic
FCY21	YER060W	Putative purine-cytosine permease	genetic	1	1	1	Negative Genetic
BNA1	YJR025C	3-hydroxyanthranilic acid dioxygenase	genetic	1	1	1	Positive Genetic
NKP2	YLR315W	Central kinetochore protein and subunit of the Ctf19 complex	physical	1	1	1	Two-hybrid
NOP19	YGR251W	Ribosome biogenesis factor	genetic	1	1	1	Negative Genetic
LYS14	YDR034C	Transcriptional activator involved in regulating lysine biosynthesis	genetic	1	1	1	Negative Genetic
ORC4	YPR162C	Subunit of the origin recognition complex (ORC)	genetic	1	1	1	Negative Genetic
MEF2	YJL102W	Mitochondrial elongation factor involved in translational elongation	genetic	1	1	1	Negative Genetic
GCD14	YJL125C	Subunit of tRNA (1-methyladenosine) methyltransferase	genetic	1	1	1	Negative Genetic
NAM2	YLR382C	Mitochondrial leucyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
FMS1	YMR020W	Polyamine oxidase	genetic	1	1	1	Positive Genetic
GLN4	YOR168W	Glutamine tRNA synthetase	genetic	1	1	1	Negative Genetic
MSF1	YPR047W	Mitochondrial phenylalanyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
GEP5	YLR091W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MRPL27	YBR282W	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
NUP192	YJL039C	Essential subunit of inner ring of nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
HEM1	YDR232W	5-aminolevulinate synthase	genetic	1	1	1	Negative Genetic
EMA35	YCR100C	Protein involved in protein sorting	genetic	1	1	1	Negative Genetic
MRX3	YBL095W	Protein that associates with mitochondrial ribosome	genetic	1	1	1	Negative Genetic
DDP1	YOR163W	Diadenosine and diphosphoinositol polyphosphate phosphatase	genetic	1	1	1	Negative Genetic
AAD4	YDL243C	Putative aryl-alcohol dehydrogenase	genetic	1	1	1	Negative Genetic
CWH43	YCR017C	GPI lipid remodelase	genetic	1	1	1	Negative Genetic
DCR2	YLR361C	Protein phosphatase	genetic	1	1	1	Positive Genetic
GIS1	YDR096W	Histone demethylase and transcription factor	genetic	1	1	1	Negative Genetic
AST2	YER101C	Lipid raft associated protein	genetic	1	1	1	Negative Genetic
CIS3	YJL158C	Mannose-containing glycoprotein constituent of the cell wall	genetic	1	1	1	Negative Genetic
MET8	YBR213W	Bifunctional dehydrogenase and ferrochelatase	genetic	1	1	1	Positive Genetic
COS7	YDL248W	Endosomal protein involved in turnover of plasma membrane proteins	genetic	1	1	1	Negative Genetic
HER2	YMR293C	Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex	genetic	1	1	1	Negative Genetic
CHO2	YGR157W	Phosphatidylethanolamine methyltransferase (PEMT)	genetic	1	1	1	Positive Genetic
ALG2	YGL065C	Mannosyltransferase in the N-linked glycosylation pathway	genetic	1	1	1	Positive Genetic
CDC8	YJR057W	Nucleoside monophosphate and nucleoside diphosphate kinase	genetic	1	1	1	Negative Genetic
CCW14	YLR390W-A	Covalently linked cell wall glycoprotein	genetic	1	1	1	Negative Genetic
DFG10	YIL049W	Probable polyprenol reductase	genetic	1	1	1	Positive Genetic
BSC4	YNL269W	Protein of unknown function	genetic	1	1	1	Negative Genetic
DNF3	YMR162C	Trans-golgi network aminophospholipid translocase (flippase)	genetic	1	1	1	Negative Genetic
MRX14	YDR115W	Putative mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
ECM4	YKR076W	S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR)	genetic	1	1	1	Negative Genetic
MRM2	YGL136C	Mitochondrial 2' O-ribose methyltransferase	genetic	1	1	1	Negative Genetic
MDL2	YPL270W	Mitochondrial inner membrane half-type ABC transporter	genetic	1	1	1	Positive Genetic
IZH2	YOL002C	Plasma membrane receptor for plant antifungal osmotin	genetic	1	1	1	Positive Genetic
MCO32	YGR053C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	1	1	1	Positive Genetic
ICY1	YMR195W	Protein of unknown function	genetic	1	1	1	Negative Genetic
CHM7	YJL049W	Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum	genetic	1	1	1	Negative Genetic
MSS2	YDL107W	Peripherally bound inner membrane protein of the mitochondrial matrix	genetic	1	1	1	Negative Genetic
HEM25	YDL119C	Mitochondrial glycine transporter	genetic	1	1	1	Negative Genetic
LSB6	YJL100W	Type II phosphatidylinositol 4-kinase	genetic	1	1	1	Positive Genetic
DFR1	YOR236W	Dihydrofolate reductase involved in tetrahydrofolate biosynthesis	genetic	1	1	1	Negative Genetic
ATG22	YCL038C	Vacuolar integral membrane protein required for efflux of amino acids	genetic	1	1	1	Positive Genetic
FLX1	YIL134W	Mitochondrial flavin adenine dinucleotide transporter	genetic	1	1	1	Positive Genetic
GPI8	YDR331W	Catalytic subunit of the ER membrane GPI transamidase complex	genetic	1	1	1	Negative Genetic
AIM33	YML087C	Protein of unknown function, highly conserved across species	genetic	1	1	1	Positive Genetic
BNA4	YBL098W	Kynurenine 3-monooxygenase	genetic	1	1	1	Negative Genetic
MSH1	YHR120W	DNA-binding protein of the mitochondria	genetic	1	1	1	Negative Genetic
ATP23	YNR020C	Putative metalloprotease of the mitochondrial inner membrane	genetic	1	1	1	Negative Genetic
MRX8	YDR336W	Protein that associates with mitochondrial ribosome	genetic	1	1	1	Negative Genetic
GPI11	YDR302W	ER membrane protein involved in a late step of GPI anchor assembly	genetic	1	1	1	Negative Genetic
PET117	YER058W	Assembly factor that couples heme a synthesis to complex IV assembly	genetic	1	1	1	Negative Genetic
MMT1	YMR177W	Putative metal transporter involved in mitochondrial iron accumulation	genetic	1	1	1	Negative Genetic
PHM7	YOL084W	Protein of unknown function	genetic	1	1	1	Negative Genetic
ADF1	YCL058W-A	Transcriptional repressor encoded by the FYV5 antisense strand	genetic	1	1	1	Negative Genetic