Standard name Systematic name Name description Description
PRP21 YJL203W Subunit of the SF3a splicing factor complex Subunit of the SF3a splicing factor complex; required for spliceosome assembly
Visualize the interactome of PRP21
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.93 0.887 0.946
Mito NaN 0.289 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleus 2490

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRP21 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 11 3 10 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 10 3 9 Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 3 3 3 Synthetic Rescue, Synthetic Lethality, Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NNK1 YKL171W Protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome physical 2 2 2 Affinity Capture-MS, Co-purification
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 2 2 Positive Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation- exonuclease evidence
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 2 1 2 Negative Genetic, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 2 1 2 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TDA8 YAL064C-A Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 2 1 2 Negative Genetic, Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SPG1 YGR236C Protein required for high temperature survival during stationary phase genetic 2 1 2 Negative Genetic, Negative Genetic
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 2 1 2 Negative Genetic, Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 2 1 2 Negative Genetic, Negative Genetic
STE23 YLR389C Metalloprotease genetic 2 1 2 Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 1 2 Negative Genetic, Negative Genetic
UNG1 YML021C Uracil-DNA glycosylase genetic 2 1 2 Negative Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 1 2 Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 2 1 2 Negative Genetic, Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 2 1 2 Negative Genetic, Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 2 1 2 Negative Genetic, Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
FUM1 YPL262W Fumarase genetic 2 1 2 Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 2 1 2 Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 2 1 2 Negative Genetic, Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Negative Genetic, Negative Genetic
BAP3 YDR046C Amino acid permease genetic 2 1 2 Negative Genetic, Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 2 1 2 Negative Genetic, Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 2 Negative Genetic, Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 2 1 2 Negative Genetic, Negative Genetic
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
AGA2 YGL032C Adhesion subunit of a-agglutinin of a-cells genetic 2 1 2 Negative Genetic, Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 2 1 2 Negative Genetic, Negative Genetic
NFT1 YKR103W Putative transporter of the MRP subfamily genetic 2 1 2 Negative Genetic, Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
AAT1 YKL106W Mitochondrial aspartate aminotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 1 1 Negative Genetic, Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 2 1 1 Negative Genetic, Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 2 1 1 Negative Genetic, Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 2 1 1 Negative Genetic, Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 2 1 1 Negative Genetic, Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CEF1 YMR213W Essential splicing factor physical 1 1 1 Affinity Capture-MS
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase physical 1 1 1 Two-hybrid
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase physical 1 1 1 Two-hybrid
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSH155 YMR288W U2-snRNP associated splicing factor physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Positive Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
SMX2 YFL017W-A Core Sm protein Sm G physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Two-hybrid
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Two-hybrid
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Two-hybrid
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
YEL023C YEL023C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PRP4 YPR178W Splicing factor physical 1 1 1 Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Synthetic Rescue
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Negative Genetic
YEH2 YLR020C Steryl ester hydrolase genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Negative Genetic
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
YOR019W YOR019W Protein of unknown function genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Positive Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Positive Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Positive Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
TRE2 YOR256C Transferrin receptor-like protein genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TRX3 YCR083W Mitochondrial thioredoxin genetic 1 1 1 Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
SHU2 YDR078C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
YGR283C YGR283C Putative methyltransferase genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
YHR022C-A YHR022C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
THI11 YJR156C Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
REX3 YLR107W RNA exonuclease genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SPS19 YNL202W Peroxisomal 2,4-dienoyl-CoA reductase genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YOL166W-A YOL166W-A Protein of unknown function genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase genetic 1 1 1 Negative Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Positive Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
YLR363W-A YLR363W-A Protein of unknown function genetic 1 1 1 Negative Genetic
TRM2 YKR056W tRNA methyltransferase genetic 1 1 1 Negative Genetic
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
CAR2 YLR438W L-ornithine transaminase (OTAse) genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing physical 1 1 1 Two-hybrid
FAA4 YMR246W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor physical 1 1 1 Affinity Capture-MS
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
GUF1 YLR289W Mitochondrial matrix GTPase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 1 1 1 Affinity Capture-MS
BUD9 YGR041W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Positive Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
POL4 YCR014C DNA polymerase IV genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Positive Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Positive Genetic
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Positive Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Negative Genetic
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Synthetic Lethality
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Negative Genetic
PET309 YLR067C Specific translational activator for the COX1 mRNA physical 1 1 1 Two-hybrid
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Negative Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p physical 1 1 1 Two-hybrid
IZH4 YOL101C Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
ICL1 YER065C Isocitrate lyase genetic 1 1 1 Negative Genetic
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Negative Genetic
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase genetic 1 1 1 Negative Genetic
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase physical 1 1 1 Affinity Capture-MS
DIN7 YDR263C Mitochondrial nuclease functioning in DNA repair and replication genetic 1 1 1 Negative Genetic
DNF1 YER166W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen genetic 1 1 1 Negative Genetic
DUS1 YML080W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
PAU8 YAL068C Protein of unknown function genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Negative Genetic
MET3 YJR010W ATP sulfurylase genetic 1 1 1 Negative Genetic
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Negative Genetic
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
ASP3-4 YLR160C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
FSH3 YOR280C Putative serine hydrolase genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MRX19 YDL183C Protein that may form an active mitochondrial KHE system genetic 1 1 1 Negative Genetic
POF1 YCL047C Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) genetic 1 1 1 Negative Genetic
BDS1 YOL164W Bacterially-derived sulfatase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
HXT13 YEL069C Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic
NPP2 YEL016C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
PAU9 YBL108C-A Protein of unknown function genetic 1 1 1 Negative Genetic