Standard name Systematic name Name description Description
NHP6A YPR052C High-mobility group (HMG) protein High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
Visualize the interactome of NHP6A
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 83

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.131 NaN NaN
Nucleolus 0.080 0.111 0.193
Nucleus 0.862 0.927 0.885

GFP localization & abundance

GFP localization GFP abundance
nucleus 3870

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NHP6A 7 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 6 3 6 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 6 3 4 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue
MSC1 YML128C Protein of unknown function genetic 4 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 4 3 3 Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 3 3 2 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis physical 3 2 2 Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
SPT15 YER148W TATA-binding protein (TBP) genetic 3 1 2 Dosage Rescue, Dosage Rescue, Dosage Rescue
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 2 2 Negative Genetic, Synthetic Rescue
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HTA1 YDR225W Histone H2A physical 2 2 2 PCA, Reconstituted Complex
HTB1 YDR224C Histone H2B physical 2 2 2 PCA, Reconstituted Complex
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-MS, PCA
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
YBR090C YBR090C Putative protein of unknown function genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 2 1 2 PCA, PCA
BRF1 YGR246C TFIIIB B-related factor genetic 2 1 2 Dosage Rescue, Dosage Rescue
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 1 Synthetic Lethality, Dosage Rescue
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 2 2 1 Synthetic Lethality, Dosage Rescue
RPB4 YJL140W RNA polymerase II subunit B32 physical 2 2 1 PCA, Co-localization
SPT6 YGR116W Nucleosome remodeling protein genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
BIM1 YER016W Microtubule plus end-tracking protein genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TDA10 YGR205W ATP-binding protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RTT105 YER104W Chaperone for Replication Protein A complex (RPA) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HCA4 YJL033W DEAD box RNA helicase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GSY2 YLR258W Glycogen synthase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HTA2 YBL003C Histone H2A regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HTA1 YDR225W Histone H2A regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HTB2 YBL002W Histone H2B regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HTB1 YDR224C Histone H2B regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HHT2 YNL031C Histone H3 regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HHT1 YBR010W Histone H3 regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HHF2 YNL030W Histone H4 regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HHF1 YBR009C Histone H4 regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HSP82 YPL240C Hsp90 chaperone regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UPS2 YLR168C Mitochondrial intermembrane space protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSM10 YDR041W Mitochondrial ribosomal protein of the small subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PGM2 YMR105C Phosphoglucomutase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LGE1 YPL055C Protein involved in histone H2B ubiquitination regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBR085C-A YBR085C-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ANR2 YKL047W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AIM26 YKL037W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR257W YLR257W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RTC3 YHR087W Protein of unknown function involved in RNA metabolism regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MTL1 YGR023W Putative plasma membrane sensor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR152C YLR152C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AKL1 YBR059C Ser/Thr protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUL1 YKL034W Subunit of the DSC ubiquitin ligase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATG42 YBR139W Vacuolar serine-type carboxypeptidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BTN2 YGR142W v-SNARE binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Positive Genetic
ENP2 YGR145W Component of the SSU genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Dosage Rescue
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
GCN2 YDR283C Protein kinase physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 1 1 1 PCA
HHF1 YBR009C Histone H4 genetic 1 1 1 Dosage Lethality
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 PCA
HTB2 YBL002W Histone H2B physical 1 1 1 PCA
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 PCA
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 PCA
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 PCA
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
DDC1 YPL194W DNA damage checkpoint protein physical 1 1 1 PCA
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Positive Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 genetic 1 1 1 Dosage Lethality
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Dosage Rescue
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Phenotypic Suppression
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Reconstituted Complex
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Lethality
NHP6B YBR089C-A High-mobility group (HMG) protein physical 1 1 1 Co-purification
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 PCA
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 PCA
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Phenotypic Suppression
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage physical 1 1 1 PCA
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 PCA
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 1 1 1 PCA
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 1 1 1 PCA
TFB4 YPR056W Subunit of TFIIH complex physical 1 1 1 PCA
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit physical 1 1 1 PCA
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 PCA
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex physical 1 1 1 PCA
TFA2 YKR062W TFIIE small subunit physical 1 1 1 PCA
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci physical 1 1 1 PCA
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 PCA
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
TFA1 YKL028W TFIIE large subunit physical 1 1 1 PCA
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) physical 1 1 1 PCA
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 PCA
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Lethality
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Rescue
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Dosage Rescue
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Dosage Rescue
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Synthetic Lethality
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Phenotypic Suppression
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Phenotypic Suppression
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Dosage Rescue
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 1 1 1 Synthetic Growth Defect
YIR016W YIR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Dosage Rescue
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Phenotypic Suppression
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Synthetic Lethality
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Lethality
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Rescue
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Phenotypic Suppression
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Phenotypic Suppression
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Phenotypic Suppression
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein physical 1 1 1 PCA
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Synthetic Lethality
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Phenotypic Suppression
HHT2 YNL031C Histone H3 physical 1 1 1 PCA
HPA2 YPR193C Tetrameric histone acetyltransferase physical 1 1 1 Biochemical Activity
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase physical 1 1 1 PCA
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Synthetic Growth Defect
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic