Standard name Systematic name Name description Description
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; long-lived protein that is preferentially retained in mother cells and forms cytoplasmic foci; oligomer activation requires heat-induced conformational change; also has mRNA binding activity
Visualize the interactome of HSP26
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 162

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.966 0.932 0.988
Mito 0.081 0.051 NaN

GFP localization & abundance

GFP localization GFP abundance
ambiguous 19300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HSP26 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 4 3 4 Protein-peptide, Reconstituted Complex, Reconstituted Complex, Two-hybrid
ESC2 YDR363W Sumo-like domain protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator regulation 2 2 2 chromatin immunoprecipitation-chip evidence, RNA-sequencing evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 2 2 2 chromatin immunoprecipitation-chip evidence, RNA-sequencing evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 1 2 Negative Genetic, Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 2 Negative Genetic, Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 1 2 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 2 1 1 PCA, PCA
RPP2A YOL039W Ribosomal protein P2 alpha physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
HCM1 YCR065W Forkhead transcription factor regulation 1 1 1 quantitative polymerase chain reaction evidence
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPN1 YPR133C Protein involved in RNA polymerase II transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NHP6A YPR052C High-mobility group (HMG) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes regulation 1 1 1 chromatin immunoprecipitation-seq evidence
TOA2 YKL058W TFIIA small subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex regulation 1 1 1 reverse transcription polymerase chain reaction evidence
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-Western
HRK1 YOR267C Protein kinase physical 1 1 1 Biochemical Activity
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase genetic 1 1 1 Phenotypic Enhancement
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III physical 1 1 1 Affinity Capture-MS
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-MS
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-MS
ADY3 YDL239C Protein required for spore wall formation physical 1 1 1 Two-hybrid
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CCP1 YKR066C Mitochondrial cytochrome-c peroxidase physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Affinity Capture-MS
TFB4 YPR056W Subunit of TFIIH complex physical 1 1 1 Affinity Capture-MS
UPC2 YDR213W Sterol regulatory element binding protein physical 1 1 1 Affinity Capture-MS
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase physical 1 1 1 Affinity Capture-MS
POL32 YJR043C Third subunit of DNA polymerase delta physical 1 1 1 Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Two-hybrid
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Two-hybrid
TAE1 YBR261C AdoMet-dependent proline methyltransferase physical 1 1 1 Two-hybrid
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Phenotypic Enhancement
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Reconstituted Complex
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
TOP3 YLR234W DNA Topoisomerase III physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity genetic 1 1 1 Phenotypic Enhancement
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p genetic 1 1 1 Phenotypic Enhancement
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
KRE29 YER038C Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Negative Genetic
YGR016W YGR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR153W YGR153W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
YLR159W YLR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNR061C YNR061C Protein of unknown function genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SWT1 YOR166C RNA endoribonuclease involved in perinuclear mRNP quality control genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Positive Genetic
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Negative Genetic
ZIP2 YGL249W Meiosis-specific protein genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
RNH202 YDR279W Ribonuclease H2 subunit genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic