Standard name Systematic name Name description Description
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex Catalytic subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p
Visualize the interactome of SNF2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.193 0.236 0.133
Nucleus 0.872 0.843 0.845
Mito NaN 0.087 0.279

GFP localization & abundance

GFP localization GFP abundance
nucleus 217

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SNF2 10 0 0 0 1

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 20 4 18 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 17 4 15 Affinity Capture-Western, Two-hybrid, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 15 3 14 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 13 4 13 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 12 3 11 Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 11 4 11 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex physical 9 4 7 Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex physical 8 3 8 Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 8 3 8 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex physical 8 3 7 Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 7 3 7 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
ASF1 YJL115W Nucleosome assembly factor genetic 6 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 4 3 4 Affinity Capture-Western, Affinity Capture-Western, Co-localization, PCA
NHP6A YPR052C High-mobility group (HMG) protein genetic 4 3 3 Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect
HHT2 YNL031C Histone H3 physical 3 2 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 3 1 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 3 2 Phenotypic Suppression, Synthetic Rescue, Dosage Rescue
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 3 3 1 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 3 2 1 Reconstituted Complex, Reconstituted Complex, Far Western
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
ASF1 YJL115W Nucleosome assembly factor physical 2 2 2 Co-localization, Affinity Capture-Western
HHF1 YBR009C Histone H4 physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
HHF2 YNL030W Histone H4 physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 2 2 2 Reconstituted Complex, Co-localization
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 2 2 2 Biochemical Activity, Co-localization
HIR1 YBL008W Subunit of the HIR complex physical 2 2 2 Affinity Capture-Western, Co-localization
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 2 2 2 PCA, Affinity Capture-Western
DGA1 YOR245C Diacylglycerol acyltransferase genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HHF1 YBR009C Histone H4 genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SPT6 YGR116W Nucleosome remodeling protein genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
HAP4 YKL109W Transcription factor physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CUP1-1 YHR053C Metallothionein regulation 2 2 1 chromatin immunoprecipitation evidence, quantitative reverse transcription polymerase chain reaction evidence
CUP1-2 YHR055C Metallothionein regulation 2 2 1 chromatin immunoprecipitation evidence, quantitative reverse transcription polymerase chain reaction evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) genetic 2 2 1 Synthetic Lethality, Dosage Rescue
TOA2 YKL058W TFIIA small subunit genetic 2 2 1 Synthetic Lethality, Dosage Rescue
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
NRG1 YDR043C Transcriptional repressor genetic 2 2 1 Dosage Rescue, Synthetic Rescue
RLM1 YPL089C MADS-box transcription factor physical 2 2 1 Affinity Capture-Western, Co-localization
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HHT1 YBR010W Histone H3 genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MAC1 YMR021C Copper-sensing transcription factor physical 2 1 1 Co-localization, Co-localization
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GTT2 YLL060C Glutathione S-transferase capable of homodimerization regulation 1 1 1 reverse transcription polymerase chain reaction evidence
INM1 YHR046C Inositol monophosphatase regulation 1 1 1 chromatin immunoprecipitation-qPCR evidence
SUC2 YIL162W Invertase regulation 1 1 1 enzymatic activity assay evidence
GTO1 YGR154C Omega-class glutathione transferase regulation 1 1 1 reverse transcription polymerase chain reaction evidence
SPL2 YHR136C Protein with similarity to cyclin-dependent kinase inhibitors regulation 1 1 1 northern blot evidence
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex regulation 1 1 1 northern blot evidence
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) regulation 1 1 1 reverse transcription polymerase chain reaction evidence
HO YDL227C Site-specific endonuclease regulation 1 1 1 beta-galactosidase reporter gene assay evidence
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity regulation 1 1 1 reverse transcription polymerase chain reaction evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Lethality
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Lethality
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Phenotypic Enhancement
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling physical 1 1 1 Co-crystal Structure
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Positive Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex physical 1 1 1 PCA
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
ADA2 YDR448W Transcription coactivator physical 1 1 1 Co-localization
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Synthetic Growth Defect
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
MRPL16 YBL038W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Positive Genetic
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways physical 1 1 1 Affinity Capture-MS
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
MSH3 YCR092C Mismatch repair protein genetic 1 1 1 Negative Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Co-localization
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Lethality
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Co-localization
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Phenotypic Enhancement
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Positive Genetic
HTA1 YDR225W Histone H2A physical 1 1 1 Reconstituted Complex
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes physical 1 1 1 Reconstituted Complex
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
YGR161C-C YGR161C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Synthetic Rescue
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Phenotypic Enhancement
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SRB4 YER022W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Synthetic Growth Defect
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Lethality
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Lethality
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Dosage Rescue
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Phenotypic Suppression
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Positive Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Positive Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Positive Genetic
YKL091C YKL091C Putative phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Reconstituted Complex
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Positive Genetic
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Synthetic Rescue
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Synthetic Growth Defect
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Growth Defect
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Phenotypic Suppression
HIR2 YOR038C Subunit of HIR nucleosome assembly complex physical 1 1 1 Affinity Capture-Western
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Synthetic Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Co-localization
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Affinity Capture-MS
GAL3 YDR009W Transcriptional regulator genetic 1 1 1 Phenotypic Enhancement
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Affinity Capture-MS
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Synthetic Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Positive Genetic
SIR3 YLR442C Silencing protein genetic 1 1 1 Synthetic Rescue
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Enhancement
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Positive Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
MSN2 YMR037C Stress-responsive transcriptional activator physical 1 1 1 Co-localization
HPC2 YBR215W Subunit of the HIR complex physical 1 1 1 Co-localization
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Co-localization
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Synthetic Lethality
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Phenotypic Enhancement
PHO80 YOL001W Cyclin genetic 1 1 1 Phenotypic Suppression
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci physical 1 1 1 Affinity Capture-Western
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Dosage Rescue
HSF1 YGL073W Trimeric heat shock transcription factor physical 1 1 1 Co-localization
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Two-hybrid
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
CAT8 YMR280C Zinc cluster transcriptional activator genetic 1 1 1 Phenotypic Enhancement
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Positive Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Positive Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
RPL36B YPL249C-A Ribosomal 60S subunit protein L36B physical 1 1 1 Affinity Capture-MS
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
PBP4 YDL053C Pbp1p binding protein physical 1 1 1 Affinity Capture-MS
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
RPL36A YMR194W Ribosomal 60S subunit protein L36A physical 1 1 1 Affinity Capture-MS
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
RPL34B YIL052C Ribosomal 60S subunit protein L34B physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
RTT106 YNL206C Histone chaperone physical 1 1 1 Co-localization
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 1 1 1 Negative Genetic
FAA3 YIL009W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Phenotypic Enhancement
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Synthetic Growth Defect
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
ERD2 YBL040C HDEL receptor genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Positive Genetic