ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
physical |
11 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
physical |
9 |
3 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
7 |
3 |
7 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
physical |
7 |
3 |
7 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
6 |
3 |
6 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
6 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
6 |
4 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue, Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
5 |
2 |
5 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-RNA |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
3 |
2 |
3 |
Co-localization, Co-localization, Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
3 |
2 |
3 |
Co-localization, Co-localization, Affinity Capture-MS |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
3 |
2 |
3 |
Negative Genetic, Positive Genetic, Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Co-fractionation |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSC7 |
YHR039C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OSM1 |
YJR051W |
Fumarate reductase, catalyzes the reduction of fumarate to succinate |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PCL8 |
YPL219W |
Cyclin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRI1 |
YPR118W |
5'-methylthioribose-1-phosphate isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAF16 |
YFL028C |
Part of evolutionarily-conserved CCR4-NOT regulatory complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Rescue |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Rescue |
TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Growth Defect |
DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Rescue |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Suppression |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
SDH7 |
YDR511W |
Mitochondrial protein involved in assembly of succinate dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CRR1 |
YLR213C |
Putative glycoside hydrolase of the spore wall envelope |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
DAK1 |
YML070W |
Dihydroxyacetone kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Co-crystal Structure |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Co-purification |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO26 |
YPR187W |
RNA polymerase subunit ABC23 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR338W |
YOR338W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC11 |
YOR339C |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NDD1 |
YOR372C |
Transcriptional activator essential for nuclear division |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAG1 |
YJR004C |
Alpha-agglutinin of alpha-cells |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDE2 |
YDL085W |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
JIP4 |
YDR475C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMD8 |
YFR048W |
Cytosolic protein required for sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNT2 |
YGL257C |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO16 |
YHR153C |
Meiosis-specific protein involved in synaptonemal complex assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX1 |
YLR043C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCD1 |
YLR151C |
8-oxo-dGTP diphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAF1 |
YMR102C |
Sterol-binding beta-propeller protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSS11 |
YMR164C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR8 |
YLR266C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUS5 |
YLR165C |
Pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT5 |
YDL093W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBG2 |
YGR173W |
Protein with a role in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL132W |
YJL132W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUT7 |
YLR283W |
Regulator of mitochondrial proline metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIN3 |
YPR154W |
Negative regulator of actin nucleation-promoting factor activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM4 |
YOL062C |
Cargo-binding mu subunit of AP-2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR3 |
YMR052W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUP2 |
YGL166W |
Copper-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDP1 |
YNL039W |
Essential subunit of RNA polymerase III transcription factor (TFIIIB) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
physical |
1 |
1 |
1 |
Co-localization |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
AMA1 |
YGR225W |
Activator of meiotic anaphase promoting complex (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOP2 |
YGL033W |
Meiosis-specific protein that localizes to chromosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR2 |
YOR093C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTH1 |
YDR151C |
mRNA binding protein, member of the CCCH zinc finger family |
genetic |
1 |
1 |
1 |
Negative Genetic |
EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCV1 |
YFR012W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |