LAS17 |
YOR181W |
Actin assembly factor |
physical |
9 |
5 |
6 |
Two-hybrid, Affinity Capture-Western, Protein-peptide, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Luminescence, Affinity Capture-Western, PCA |
LSB1 |
YGR136W |
Negative regulator of actin nucleation-promoting factor activity |
physical |
5 |
3 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Co-localization |
UBI4 |
YLL039C |
Ubiquitin |
physical |
4 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Co-localization |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
GYL1 |
YMR192W |
Putative GTPase activating protein (GAP) with a role in exocytosis |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
YIL108W |
YIL108W |
Putative metalloendopeptidase |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMP1 |
YLL061W |
High-affinity S-methylmethionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
1 |
1 |
1 |
Co-localization |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Two-hybrid |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
physical |
1 |
1 |
1 |
Two-hybrid |
MCM6 |
YGL201C |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Two-hybrid |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Two-hybrid |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FES1 |
YBR101C |
Hsp70 (Ssa1p) nucleotide exchange factor |
physical |
1 |
1 |
1 |
Two-hybrid |
LSB1 |
YGR136W |
Negative regulator of actin nucleation-promoting factor activity |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPG1 |
YGL121C |
Proposed gamma subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN9 |
YPL050C |
Subunit of Golgi mannosyltransferase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
FZO1 |
YBR179C |
Mitofusin, protein involved in mitochondrial outer membrane fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMG2 |
YLR450W |
HMG-CoA reductase |
physical |
1 |
1 |
1 |
Two-hybrid |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
physical |
1 |
1 |
1 |
Two-hybrid |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET31 |
YPL038W |
Zinc-finger DNA-binding transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
physical |
1 |
1 |
1 |
Two-hybrid |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACF2 |
YLR144C |
Intracellular beta-1,3-endoglucanase |
physical |
1 |
1 |
1 |
Two-hybrid |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
1 |
1 |
1 |
Two-hybrid |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Two-hybrid |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
PIN3 |
YPR154W |
Negative regulator of actin nucleation-promoting factor activity |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
physical |
1 |
1 |
1 |
Two-hybrid |
RRP7 |
YCL031C |
Essential protein involved in rRNA processing and ribosome biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
physical |
1 |
1 |
1 |
Two-hybrid |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
physical |
1 |
1 |
1 |
Two-hybrid |
THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Two-hybrid |
VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Two-hybrid |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Two-hybrid |
YAL063C-A |
YAL063C-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YDL159W-A |
YDL159W-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
PCA |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL039W |
YGL039W |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBS1 |
YBR150C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD30 |
YDR419W |
DNA polymerase eta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER137C |
YER137C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
genetic |
1 |
1 |
1 |
Negative Genetic |
TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML003W |
YML003W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO19 |
YPL130W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
physical |
1 |
1 |
1 |
Two-hybrid |
ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
MCH1 |
YDL054C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDA1 |
YLR307W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM29 |
YKR074W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
MRX18 |
YBR056W |
Putative glycoside hydrolase of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE4 |
YDL231C |
Zinc finger protein containing five transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNF3 |
YMR162C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Two-hybrid |
GRS2 |
YPR081C |
Glycine-tRNA synthetase, not expressed under normal growth conditions |
physical |
1 |
1 |
1 |
Two-hybrid |
DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Positive Genetic |