Standard name Systematic name Name description Description
SIP4 YJL089W C6 zinc cluster transcriptional activator C6 zinc cluster transcriptional activator; binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
Visualize the interactome of SIP4
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SIP4 6 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SNF1 YDR477W AMP-activated S/T protein kinase physical 6 2 3 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
ICL1 YER065C Isocitrate lyase regulation 3 3 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-qPCR evidence, quantitative polymerase chain reaction evidence
PCK1 YKR097W Phosphoenolpyruvate carboxykinase regulation 3 3 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-qPCR evidence, quantitative polymerase chain reaction evidence
RAD52 YML032C Protein involved in homologous recombination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 2 1 2 Negative Genetic, Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 2 1 2 Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 2 1 2 Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSH4 YKL124W Specificity factor required for Rsp5p-dependent ubiquitination genetic 2 1 2 Negative Genetic, Negative Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 2 1 2 Negative Genetic, Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 2 1 2 Negative Genetic, Negative Genetic
FPR2 YDR519W Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) genetic 2 1 2 Negative Genetic, Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 2 1 2 Negative Genetic, Negative Genetic
FBP1 YLR377C Fructose-1,6-bisphosphatase regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, quantitative polymerase chain reaction evidence
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 2 2 1 Reconstituted Complex, Two-hybrid
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 2 2 1 Affinity Capture-Western, Two-hybrid
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 2 1 1 Negative Genetic, Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 2 1 1 Negative Genetic, Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 2 1 1 Negative Genetic, Negative Genetic
CAT8 YMR280C Zinc cluster transcriptional activator physical 2 1 1 Two-hybrid, Two-hybrid
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 2 1 1 Negative Genetic, Negative Genetic
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 2 1 1 Negative Genetic, Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TRM13 YOL125W 2'-O-methyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) regulation 1 1 1 DNA to cDNA expression microarray evidence
MDH2 YOL126C Cytoplasmic malate dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs regulation 1 1 1 DNA to cDNA expression microarray evidence
RRT15 YLR162W-A Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 quantitative polymerase chain reaction evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Biochemical Activity
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Positive Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Positive Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
DSS1 YMR287C 3'-5' exoribonuclease genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 Biochemical Activity
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
BUD9 YGR041W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Lethality
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Biochemical Activity
SIP4 YJL089W C6 zinc cluster transcriptional activator physical 1 1 1 Two-hybrid
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase genetic 1 1 1 Negative Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Positive Genetic
YJR124C YJR124C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 1 1 1 Negative Genetic
SRL2 YLR082C Protein of unknown function genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRI1 YMR233W Non-essential sumoylated protein of unknown function genetic 1 1 1 Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
YNR068C YNR068C Putative protein of unknown function genetic 1 1 1 Negative Genetic
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
CAT8 YMR280C Zinc cluster transcriptional activator genetic 1 1 1 Dosage Rescue
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Negative Genetic
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Negative Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
KIN82 YCR091W Putative serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PYP1 YNL010W Sugar alcohol phosphatase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 Biochemical Activity
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Negative Genetic
MUP3 YHL036W Low affinity methionine permease genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
CMC4 YMR194C-B Protein that localizes to the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
QDR1 YIL120W Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic