| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Positive Genetic, Positive Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BAP2 |
YBR068C |
High-affinity leucine permease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MCX1 |
YBR227C |
Non-proteolytic ATPase of the AAA family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| REX4 |
YOL080C |
Putative RNA exonuclease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AIM33 |
YML087C |
Protein of unknown function, highly conserved across species |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NDJ1 |
YOL104C |
Protein that regulates meiotic SPB cohesion and telomere clustering |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMG2 |
YLR450W |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KTI11 |
YBL071W-A |
Zn-ribbon protein that co-purifies with Dph1 and Dph2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EKI1 |
YDR147W |
Ethanolamine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAD14 |
YNL331C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COX16 |
YJL003W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTR3 |
YFR029W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPS28 |
YDR337W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMP1 |
YLR145W |
Subunit of RNase MRP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA1 |
YNL158W |
Essential component of GPI-mannosyltransferase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCL001W-B |
YCL001W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP2 |
YEL017C-A |
Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPA1 |
YER049W |
Prolyl hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFR018C |
YFR018C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPH1 |
YLR313C |
Protein involved in shmoo formation and bipolar bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSG2 |
YNL156C |
Protein involved in regulation of sterol biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTP1 |
YNL237W |
Probable type-III integral membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHA2 |
YNL316C |
Prephenate dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIR4 |
YOR009W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBI1 |
YPL272C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR160W |
YMR160W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRL1 |
YPR079W |
Membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Positive Genetic |
