Standard name Systematic name Name description Description
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p
Visualize the interactome of STH1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 64

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.348 0.332 0.387
Nucleus 0.843 0.835 0.817

GFP localization & abundance

GFP localization GFP abundance
nucleus 1990

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
STH1 3 1 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 22 4 20 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Co-purification
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 13 5 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
RSC4 YKR008W Component of the RSC chromatin remodeling complex physical 10 4 9 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 10 4 7 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 9 4 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 9 4 8 Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 9 4 8 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RSC1 YGR056W Component of the RSC chromatin remodeling complex physical 9 4 8 Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 9 4 4 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RSC58 YLR033W Component of the RSC chromatin remodeling complex physical 8 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 7 5 7 Affinity Capture-Western, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 7 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
HHT1 YBR010W Histone H3 physical 6 5 4 Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Protein-peptide
RSC9 YML127W Component of the RSC chromatin remodeling complex physical 5 3 5 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
HHF1 YBR009C Histone H4 physical 5 4 3 Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Protein-peptide
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex physical 4 3 3 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex physical 4 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
PKC1 YBL105C Protein serine/threonine kinase genetic 4 3 2 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Phenotypic Suppression
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 4 3 2 Dosage Rescue, Synthetic Lethality, Dosage Rescue, Phenotypic Suppression
RSC30 YHR056C Component of the RSC chromatin remodeling complex physical 3 3 3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
HHT2 YNL031C Histone H3 physical 3 3 3 Reconstituted Complex, Co-crystal Structure, Protein-peptide
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 3 1 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
MOT1 YPL082C Essential protein involved in regulation of transcription physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
HTB1 YDR224C Histone H2B physical 3 3 1 Affinity Capture-Western, Far Western, Reconstituted Complex
HHF2 YNL030W Histone H4 physical 2 2 2 Reconstituted Complex, Protein-peptide
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) physical 2 2 2 Co-localization, Affinity Capture-Western
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 2 2 2 Phenotypic Suppression, Synthetic Growth Defect
LDB7 YBL006C Component of the RSC chromatin remodeling complex physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HTA2 YBL003C Histone H2A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 2 Dosage Rescue, Dosage Rescue
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 1 2 Dosage Rescue, Dosage Rescue
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 2 1 2 Dosage Rescue, Dosage Rescue
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 2 1 2 Dosage Rescue, Dosage Rescue
NHP6A YPR052C High-mobility group (HMG) protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 1 Negative Genetic, Positive Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
PLC1 YPL268W Phospholipase C genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
HAP4 YKL109W Transcription factor genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
MID2 YLR332W O-glycosylated plasma membrane protein genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Positive Genetic, Negative Genetic
IRR1 YIL026C Subunit of the cohesin complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A genetic 1 1 1 Synthetic Growth Defect
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Synthetic Growth Defect
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Growth Defect
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 1 1 1 Synthetic Growth Defect
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences genetic 1 1 1 Synthetic Growth Defect
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 1 1 1 Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-Western
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Synthetic Growth Defect
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC3 YDR303C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Lethality
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
HHF1 YBR009C Histone H4 genetic 1 1 1 Synthetic Rescue
HHF2 YNL030W Histone H4 genetic 1 1 1 Synthetic Lethality
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Synthetic Rescue
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
CCM1 YGR150C Mitochondrial 15S rRNA-binding protein genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Synthetic Growth Defect
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Co-fractionation
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
NHP6B YBR089C-A High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Synthetic Growth Defect
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Growth Defect
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
HTA1 YDR225W Histone H2A genetic 1 1 1 Synthetic Growth Defect
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes physical 1 1 1 Affinity Capture-MS
RPA12 YJR063W RNA polymerase I subunit A12.2 genetic 1 1 1 Synthetic Growth Defect
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-Western
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-Western
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Growth Defect
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 1 1 1 Affinity Capture-MS
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Synthetic Growth Defect
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B genetic 1 1 1 Synthetic Growth Defect
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Synthetic Growth Defect
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-Western
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Lethality
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Synthetic Growth Defect
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Synthetic Growth Defect
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Synthetic Growth Defect
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Affinity Capture-Western
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Affinity Capture-Western
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events physical 1 1 1 Affinity Capture-Western
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Synthetic Growth Defect
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Synthetic Growth Defect
ARP5 YNL059C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
MRS1 YIR021W Splicing protein genetic 1 1 1 Synthetic Growth Defect
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Synthetic Growth Defect
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Synthetic Growth Defect
HSP150 YJL159W O-mannosylated heat shock protein genetic 1 1 1 Dosage Rescue
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Synthetic Growth Defect
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Dosage Rescue
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
HAP4 YKL109W Transcription factor physical 1 1 1 Affinity Capture-Western
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A genetic 1 1 1 Synthetic Growth Defect
HHT2 YNL031C Histone H3 genetic 1 1 1 Synthetic Growth Defect
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin genetic 1 1 1 Synthetic Growth Defect
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Synthetic Growth Defect
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Dosage Rescue
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Synthetic Growth Defect
YOR302W YOR302W CPA1 uORF genetic 1 1 1 Synthetic Growth Defect
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Growth Defect
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Growth Defect
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
VMA22 YHR060W Protein that is required for vacuolar H+-ATPase (V-ATPase) function genetic 1 1 1 Synthetic Growth Defect
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 1 1 1 Synthetic Growth Defect
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Synthetic Growth Defect
MAP1 YLR244C Methionine aminopeptidase genetic 1 1 1 Synthetic Growth Defect
BUD23 YCR047C Ribosome biogenesis factor genetic 1 1 1 Synthetic Growth Defect
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Growth Defect
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Synthetic Growth Defect
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Synthetic Growth Defect
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Synthetic Growth Defect
RPL13B YMR142C Ribosomal 60S subunit protein L13B genetic 1 1 1 Synthetic Growth Defect
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
ARN2 YHL047C Transporter genetic 1 1 1 Synthetic Growth Defect
GGC1 YDL198C Mitochondrial GTP/GDP transporter genetic 1 1 1 Synthetic Growth Defect
MRPL51 YPR100W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
EFG1 YGR271C-A Ribosome biogenesis factor required for maturation of 18S rRNA genetic 1 1 1 Synthetic Growth Defect
RPL39 YJL189W Ribosomal 60S subunit protein L39 genetic 1 1 1 Synthetic Growth Defect
POS5 YPL188W Mitochondrial NADH kinase genetic 1 1 1 Synthetic Growth Defect
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Dosage Rescue
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Synthetic Growth Defect
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ARG2 YJL071W Acetylglutamate synthase (glutamate N-acetyltransferase) genetic 1 1 1 Synthetic Growth Defect
HNT3 YOR258W DNA 5' AMP hydrolase involved in DNA repair genetic 1 1 1 Synthetic Growth Defect
MSY1 YPL097W Mitochondrial tyrosyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect