Standard name Systematic name Name description Description
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex H subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF
Visualize the interactome of GCV3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi 0.118 0.071 0.352
Mito 0.971 0.857 0.680
Nucleolus 0.176 0.086 0.176
Vac/Vac Memb 0.059 0.157 0.088

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 3510

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GCV3 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0509 (glycine-cleavage system (lipoamide)), r_0505 (glycine-cleavage complex (lipoamide)), r_0508 (glycine-cleavage complex (lipoylprotein)), r_0507 (glycine-cleavage complex (lipoylprotein)), r_0506 (glycine-cleavage complex (lipoylprotein)), r_0501 (glycine cleavage system), r_0504 (glycine-cleavage complex (lipoamide)), r_1030 (tetrahydrofolate aminomethyltransferase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BAS1 YKR099W Myb-related transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 2 2 1 Positive Genetic, Negative Genetic
CIT1 YNR001C Mitochondrial citrate synthase genetic 2 1 1 Positive Genetic, Positive Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 2 1 1 Negative Genetic, Negative Genetic
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 2 1 1 Negative Genetic, Negative Genetic
LSC2 YGR244C Beta subunit of succinyl-CoA ligase genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
ACH1 YBL015W Protein with CoA transferase activity genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
FAA2 YER015W Medium chain fatty acyl-CoA synthetase genetic 1 1 1 Phenotypic Suppression
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
GAS5 YOL030W 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Positive Genetic
LIP2 YLR239C Lipoyl ligase physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Positive Genetic
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Negative Genetic
ODC1 YPL134C Mitochondrial inner membrane transporter genetic 1 1 1 Positive Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
RMA1 YKL132C Putative dihydrofolate synthetase genetic 1 1 1 Negative Genetic
IRC7 YFR055W Cysteine desulphydrase, enables growth on cysteine as nitrogen source genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Positive Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
UTR1 YJR049C ATP-NADH kinase genetic 1 1 1 Positive Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
SGA1 YIL099W Intracellular sporulation-specific glucoamylase genetic 1 1 1 Positive Genetic
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Negative Genetic
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Lethality
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Lethality
ATF2 YGR177C Alcohol acetyltransferase genetic 1 1 1 Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Positive Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
ELO1 YJL196C Elongase I, medium-chain acyl elongase genetic 1 1 1 Positive Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic