Standard name Systematic name Name description Description
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway; involved in maintenance of cell wall integrity and recovery from heat shock; required for the arrest of secretion response; WSC2 has a paralog, WSC3, that arose from the whole genome duplication
Visualize the interactome of WSC2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 58

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.114 0.125 0.089
Budsite 0.055 NaN NaN
Cell Periphery 0.411 0.420 0.368
Cort. Patches 0.479 0.331 0.372
Cytoplasm 0.233 0.398 0.336
SpindlePole 0.082 NaN 0.099
Mito NaN NaN 0.056

GFP localization & abundance

GFP localization GFP abundance
cell periphery low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
WSC2 0 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 3 3 2 Dosage Rescue, Phenotypic Enhancement, Negative Genetic
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 2 1 2 PCA, PCA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 2 1 2 Dosage Rescue, Dosage Rescue
MID2 YLR332W O-glycosylated plasma membrane protein genetic 2 1 2 Dosage Rescue, Dosage Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Positive Genetic, Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HTB1 YDR224C Histone H2B genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
AIM25 YJR100C Mitochondria protein of unknown function genetic 1 1 1 Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Dosage Rescue
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Dosage Rescue
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-RNA
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Dosage Rescue
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Rescue
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic physical 1 1 1 PCA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 1 1 1 Dosage Rescue
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Dosage Rescue
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 PCA
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Dosage Rescue
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Dosage Rescue
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Dosage Rescue
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Dosage Rescue
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Phenotypic Suppression
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Dosage Rescue
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Dosage Rescue
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 Two-hybrid
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 1 1 1 Phenotypic Suppression
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 1 1 1 PCA
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Dosage Rescue
BPH1 YCR032W Protein homologous to Chediak-Higashi syndrome and Beige proteins genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain physical 1 1 1 PCA
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
RFS1 YBR052C Protein of unknown function physical 1 1 1 PCA
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 PCA
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 PCA
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 1 1 1 Positive Genetic
YGL108C YGL108C Protein of unknown function, predicted to be palmitoylated physical 1 1 1 PCA
WSC3 YOL105C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 PCA
WSC3 YOL105C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Dosage Rescue
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 PCA
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 1 1 1 Negative Genetic
YPL162C YPL162C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
ECM15 YBL001C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 1 1 1 Negative Genetic
MRS4 YKR052C Iron transporter of the mitochondrial carrier family genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Synthetic Growth Defect
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
NCA3 YJL116C Protein involved in mitochondrion organization genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic