ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
3 |
Synthetic Haploinsufficiency, Negative Genetic, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
FPR4 |
YLR449W |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSI1 |
YMR025W |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCP1 |
YHR042W |
NADP-cytochrome P450 reductase |
physical |
1 |
1 |
1 |
PCA |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
physical |
1 |
1 |
1 |
PCA |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH3 |
YKL141W |
Subunit of succinate dehydrogenase and of TIM22 translocase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMT5 |
YDL093W |
Protein O-mannosyltransferase |
physical |
1 |
1 |
1 |
PCA |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP9 |
YER098W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM13 |
YGR181W |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYF2 |
YGR129W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS4 |
YKR052C |
Iron transporter of the mitochondrial carrier family |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBI1 |
YPL272C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |