Standard name Systematic name Name description Description
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant
Visualize the interactome of VMA2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.255 0.336 0.161
Vac/Vac Memb 0.740 0.642 0.767
Golgi NaN NaN 0.282

GFP localization & abundance

GFP localization GFP abundance
vacuolar membrane 131000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VMA2 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1086 (V-ATPase, vacuole), r_1085 (V-ATPase, Golgi)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 13 6 11 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Co-fractionation, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-purification
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 11 4 11 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 9 6 9 Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Protein-peptide, Co-crystal Structure
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 7 4 7 Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, FRET
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 6 4 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Protein-peptide, FRET, Reconstituted Complex
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 4 4 4 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Protein-peptide
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CNB1 YKL190W Calcineurin B genetic 3 3 2 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Suppression
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
TLG2 YOL018C Syntaxin-like t-SNARE genetic 2 2 2 Synthetic Lethality, Negative Genetic
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 2 2 Dosage Lethality, Phenotypic Suppression
ELO3 YLR372W Elongase genetic 2 2 2 Negative Genetic, Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 2 2 2 Phenotypic Suppression, Synthetic Growth Defect
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
TSA1 YML028W Thioredoxin peroxidase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 2 2 1 Phenotypic Enhancement, Dosage Growth Defect
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ADA2 YDR448W Transcription coactivator genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-Western
RBG2 YGR173W Protein with a role in translation genetic 1 1 1 Phenotypic Enhancement
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Synthetic Lethality
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Synthetic Lethality
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Synthetic Lethality
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Co-fractionation
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Positive Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Lethality
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Affinity Capture-MS
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
YMD8 YML038C Putative nucleotide sugar transporter physical 1 1 1 Affinity Capture-MS
YPR097W YPR097W Protein that contains a PX domain and binds phosphoinositides physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 1 1 1 Synthetic Lethality
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Lethality
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Rescue
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Lethality
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Negative Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Synthetic Lethality
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Synthetic Lethality
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Lethality
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Dosage Lethality
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Phenotypic Enhancement
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Phenotypic Enhancement
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Negative Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Dosage Rescue
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Dosage Lethality
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Affinity Capture-MS
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Lethality
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 1 1 1 Affinity Capture-MS
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Dosage Rescue
ACO2 YJL200C Putative mitochondrial aconitase isozyme genetic 1 1 1 Negative Genetic
GNP1 YDR508C Broad specificity amino acid permease physical 1 1 1 Affinity Capture-MS
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Affinity Capture-MS
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Rescue
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Synthetic Lethality
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Affinity Capture-Western
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' physical 1 1 1 Co-fractionation
ERV14 YGL054C COPII-coated vesicle protein physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 1 1 1 Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 1 1 1 Negative Genetic
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Phenotypic Enhancement
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Positive Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Synthetic Lethality
HAM1 YJR069C Nucleoside triphosphate pyrophosphohydrolase physical 1 1 1 Affinity Capture-MS
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Phenotypic Enhancement
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance physical 1 1 1 Affinity Capture-MS
CPR5 YDR304C Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Synthetic Growth Defect
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Positive Genetic
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 1 1 1 Negative Genetic
URA10 YMR271C Minor orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Negative Genetic
LAP3 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRG8 YPR116W Protein of unknown function physical 1 1 1 Affinity Capture-MS
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Positive Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Lethality
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Synthetic Growth Defect
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Positive Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase physical 1 1 1 Affinity Capture-MS
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Dosage Growth Defect
GPX1 YKL026C Phospholipid hydroperoxide glutathione peroxidase genetic 1 1 1 Negative Genetic
LYP1 YNL268W Lysine permease physical 1 1 1 Affinity Capture-MS
SPC2 YML055W Subunit of signal peptidase complex genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Negative Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
IRC20 YLR247C E3 ubiquitin ligase and putative helicase physical 1 1 1 Affinity Capture-MS
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 1 1 1 Negative Genetic