SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
10 |
5 |
7 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, PCA, Reconstituted Complex, Affinity Capture-Western |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
5 |
3 |
2 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
3 |
3 |
2 |
Negative Genetic, Phenotypic Suppression, Synthetic Growth Defect |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect |
SNC1 |
YAL030W |
Vesicle membrane receptor protein (v-SNARE) |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, PCA |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Lethality |
YPT31 |
YER031C |
Rab family GTPase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Positive Genetic |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HRT1 |
YOL133W |
RING-H2 domain core subunit of multiple ubiquitin ligase complexes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK10 |
YEL053C |
Non-catalytic subunit of the NatC N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN1 |
YDR122W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC53 |
YDL132W |
Cullin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD32 |
YGR262C |
Protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GTO1 |
YGR154C |
Omega-class glutathione transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCY1 |
YOR120W |
Glycerol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
physical |
1 |
1 |
1 |
Biochemical Activity |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAR066W |
YAR066W |
Putative GPI protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRI1 |
YDL216C |
Catalytic subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDR210W |
YDR210W |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHR212W-A |
YHR212W-A |
Pseudogenic fragment with similarity to flocculins |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOR1 |
YJR159W |
Sorbitol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKR018C |
YKR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YSF3 |
YNL138W-A |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOR072W-B |
YOR072W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR225C |
YLR225C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM2 |
YHL019C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISD11 |
YER048W-A |
Cysteine desulfurase (Nfs1p) activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAE1 |
YKR038C |
Highly conserved ATPase of HSP70/DnaK family |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSA2 |
YKR077W |
Putative transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUT2 |
YIL155C |
Mitochondrial glycerol-3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Positive Genetic |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
1 |
1 |
1 |
Positive Genetic |
IZH2 |
YOL002C |
Plasma membrane receptor for plant antifungal osmotin |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALP1 |
YNL270C |
Arginine transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |