Standard name Systematic name Name description Description
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis Meiosis-specific protein required for chromosome synapsis; displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for chiasma formation; in vitro, displays the ability to promote intra- and intermolecular synapsis between double-stranded DNA molecules and to fold DNA into rigid protein-DNA filaments
Visualize the interactome of HOP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HOP1 0 3 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RED1 YLR263W Protein component of the synaptonemal complex axial elements physical 9 5 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Far Western, Reconstituted Complex, Protein-peptide
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 5 5 3 Two-hybrid, Biochemical Activity, Co-localization, Protein-peptide, Co-crystal Structure
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 4 3 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Lethality
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Protein-peptide
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
REC104 YHR157W Protein involved in early stages of meiotic recombination genetic 2 1 2 Dosage Rescue, Dosage Rescue
YEL1 YBL060W Guanine nucleotide exchange factor specific for Arf3p genetic 2 1 2 Negative Genetic, Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 1 2 Negative Genetic, Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
YHR210C YHR210C Putative aldose 1-epimerase superfamily protein genetic 2 1 2 Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 2 1 2 Negative Genetic, Negative Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 2 1 2 Negative Genetic, Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
DIC1 YLR348C Mitochondrial dicarboxylate carrier genetic 2 1 2 Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 2 1 1 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 2 1 1 Negative Genetic, Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 2 1 1 Negative Genetic, Negative Genetic
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 2 1 1 Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex physical 1 1 1 Affinity Capture-MS
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Reconstituted Complex
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p physical 1 1 1 Reconstituted Complex
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p genetic 1 1 1 Phenotypic Suppression
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
ZIP2 YGL249W Meiosis-specific protein physical 1 1 1 Affinity Capture-MS
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis physical 1 1 1 Affinity Capture-MS
SPO16 YHR153C Meiosis-specific protein involved in synaptonemal complex assembly physical 1 1 1 Affinity Capture-MS
MND1 YGL183C Protein required for recombination and meiotic nuclear division genetic 1 1 1 Phenotypic Suppression
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Phenotypic Suppression
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Phenotypic Suppression
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Positive Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Phenotypic Enhancement
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
PUT1 YLR142W Proline oxidase genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 1 1 1 Phenotypic Suppression
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
HED1 YDR014W-A Meiosis-specific protein genetic 1 1 1 Synthetic Lethality
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
CUP1-2 YHR055C Metallothionein genetic 1 1 1 Negative Genetic