Standard name Systematic name Name description Description
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase Mitochondrial leucyl-tRNA synthetase; also has direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance; human homolog LARS2 can complement yeast null mutant, and is implicated in Perrault syndrome
Visualize the interactome of NAM2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 56

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.056 NaN 0.148
Mito 0.860 0.870 0.490
Vac/Vac Memb 0.079 0.127 0.060
Bud NaN NaN 0.107
Cort. Patches NaN NaN 0.081
Endosome NaN NaN 0.074
SpindlePole NaN NaN 0.181

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 2120

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NAM2 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0702 (leucyl-tRNA synthetase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BI4 Q0120 Mitochondrial mRNA maturase physical 5 2 4 Two-hybrid, Protein-RNA, Two-hybrid, Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 2 1 2 Positive Genetic, Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Synthetic Lethality
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Lethality
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Negative Genetic
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
RIF1 YBR275C Protein involved in control of DNA replication physical 1 1 1 Affinity Capture-MS
PAR32 YDL173W Low complexity protein physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
BI4 Q0120 Mitochondrial mRNA maturase genetic 1 1 1 Phenotypic Suppression
FAA3 YIL009W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Positive Genetic
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Positive Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Positive Genetic