Standard name Systematic name Name description Description
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) Essential subunit of the Dam1 complex (aka DASH complex); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases; sumoylated in an Mms21p-dependent manner; protein abundance increases in response to DNA replication stress
Visualize the interactome of ASK1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 161

CYCLoPs localization & abundance

WT1 WT2 WT3
Budneck 0.063 NaN NaN
Nucleolus 0.514 0.561 0.382
SpindlePole 0.694 0.725 0.863
Mito NaN 0.053 NaN
Peroxisome NaN 0.058 NaN

GFP localization & abundance

GFP localization GFP abundance
spindle pole 2840

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ASK1 0 2 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) physical 11 4 10 Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, Two-hybrid, Two-hybrid, Co-purification
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) physical 8 4 8 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Co-purification, Co-purification, Reconstituted Complex
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 6 4 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Co-purification, Co-purification
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 4 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Two-hybrid, Co-purification
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 4 3 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 4 3 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 4 2 4 Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-MS
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 3 2 Synthetic Growth Defect, Positive Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 3 2 2 Positive Genetic, Negative Genetic, Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 2 2 Synthetic Lethality, Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 2 2 2 Co-purification, Reconstituted Complex
CBF2 YGR140W Essential kinetochore protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Lethality, Positive Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 2 1 2 Biochemical Activity, Biochemical Activity
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 2 1 2 Negative Genetic, Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 2 1 2 Negative Genetic, Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 2 1 2 Negative Genetic, Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 1 2 Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 2 1 2 Negative Genetic, Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 2 Negative Genetic, Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 1 2 Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 2 1 2 Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 2 Negative Genetic, Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
RAS2 YNL098C GTP-binding protein genetic 2 2 1 Dosage Rescue, Synthetic Rescue
TUB2 YFL037W Beta-tubulin genetic 2 2 1 Positive Genetic, Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 2 2 1 Positive Genetic, Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 2 1 1 Negative Genetic, Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 1 1 Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 1 Negative Genetic, Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 2 1 1 Negative Genetic, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 2 1 1 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Rescue
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex physical 1 1 1 Two-hybrid
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-Western
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-Western
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Rescue
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Rescue
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Co-localization
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
DAD3 YBR233W-A Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Co-purification
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Biochemical Activity
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Reconstituted Complex
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CNN1 YFR046C Kinetochore protein physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Synthetic Growth Defect
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Rescue
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Phenotypic Suppression
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Synthetic Lethality
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Positive Genetic
CWC2 YDL209C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Positive Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Positive Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Positive Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Positive Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Positive Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Positive Genetic
MRPL31 YKL138C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
YCR023C YCR023C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YBR184W YBR184W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Negative Genetic
YER076C YER076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 1 1 1 Negative Genetic
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 1 1 1 Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Positive Genetic
PDS1 YDR113C Securin genetic 1 1 1 Negative Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
DIS3 YOL021C Exosome core complex catalytic subunit genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
RCE1 YMR274C Type II CAAX prenyl protease genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Dosage Lethality
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic