Standard name Systematic name Name description Description
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
Visualize the interactome of HSK3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HSK3 0 3 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) physical 7 4 7 Co-purification, Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Co-purification, Reconstituted Complex
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) physical 6 3 4 Co-purification, Two-hybrid, Two-hybrid, Two-hybrid, PCA, Two-hybrid
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 6 3 4 Co-purification, Two-hybrid, Two-hybrid, Two-hybrid, PCA, Two-hybrid
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 6 3 3 Co-purification, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Two-hybrid
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 4 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Two-hybrid, Co-purification
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 3 3 3 Affinity Capture-Western, Co-purification, Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 3 2 3 Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 3 2 2 Two-hybrid, PCA, Two-hybrid
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 2 2 2 Co-purification, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) physical 2 1 2 Co-purification, Co-purification
YLR031W YLR031W Putative protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
NIP100 YPL174C Large subunit of the dynactin complex physical 2 1 2 Two-hybrid, Two-hybrid
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 2 2 1 PCA, Two-hybrid
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Two-hybrid
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Two-hybrid
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
ALT2 YDR111C Catalytically inactive alanine transaminase physical 1 1 1 Two-hybrid
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest physical 1 1 1 Two-hybrid
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Two-hybrid
CIK1 YMR198W Kinesin-associated protein physical 1 1 1 Two-hybrid
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Two-hybrid
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Rescue
BNR1 YIL159W Formin physical 1 1 1 Two-hybrid
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) physical 1 1 1 Two-hybrid
MED8 YBR193C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
MFG1 YDL233W Regulator of filamentous growth physical 1 1 1 Two-hybrid
LCP5 YER127W Essential protein involved in maturation of 18S rRNA physical 1 1 1 Two-hybrid
KEG1 YFR042W Integral membrane protein of the ER physical 1 1 1 Two-hybrid
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
STP22 YCL008C Component of the ESCRT-I complex physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
SSD1 YDR293C Translational repressor physical 1 1 1 Two-hybrid
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family physical 1 1 1 Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Two-hybrid
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Two-hybrid
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex physical 1 1 1 Two-hybrid
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 1 1 1 Two-hybrid
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Two-hybrid
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Two-hybrid
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Two-hybrid
MRPS17 YMR188C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Two-hybrid
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
YPL216W YPL216W Putative protein of unknown function physical 1 1 1 Two-hybrid
DAD3 YBR233W-A Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Co-purification
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Two-hybrid
AHC2 YCR082W Component of the ADA histone acetyltransferase complex physical 1 1 1 Two-hybrid
ERP3 YDL018C Protein with similarity to Emp24p and Erv25p physical 1 1 1 Two-hybrid
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 1 1 1 Two-hybrid
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 1 1 1 Two-hybrid