Standard name Systematic name Name description Description
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER Sterol-binding protein that localizes to puncta in the cortical ER; sterol binding occurs via two StART-like domains; one of six StART-like domain-containing proteins in yeast that may be involved in intracellular sterol transfer between membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Visualize the interactome of LAM4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LAM4 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
YSP2 YDR326C Sterol-binding protein genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator physical 2 1 1 Two-hybrid, Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 2 1 1 Two-hybrid, Two-hybrid
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex physical 2 1 1 Two-hybrid, Two-hybrid
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 2 1 1 Two-hybrid, Two-hybrid
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 2 1 1 Two-hybrid, Two-hybrid
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 2 1 1 Two-hybrid, Two-hybrid
SHE9 YDR393W Protein required for normal mitochondrial morphology physical 2 1 1 Two-hybrid, Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 2 1 1 Two-hybrid, Two-hybrid
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER physical 2 1 1 Two-hybrid, Two-hybrid
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 2 1 1 Two-hybrid, Two-hybrid
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 1 Two-hybrid, Two-hybrid
PAC1 YOR269W Regulator of dynein, involved in intracellular transport physical 2 1 1 Two-hybrid, Two-hybrid
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 2 1 1 Two-hybrid, Two-hybrid
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 2 1 1 Two-hybrid, Two-hybrid
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YPK1 YKL126W S/T protein kinase regulation 1 1 1 protein kinase assay evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Two-hybrid
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Two-hybrid
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 1 1 1 Two-hybrid
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Two-hybrid
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Two-hybrid
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
JNM1 YMR294W Component of the yeast dynactin complex physical 1 1 1 Two-hybrid
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p physical 1 1 1 Two-hybrid
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Two-hybrid
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Two-hybrid
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
CSA1 YPR174C Protein of unknown function physical 1 1 1 Two-hybrid
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Two-hybrid
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Two-hybrid
VPS60 YDR486C Protein involved in late endosome to vacuole transport physical 1 1 1 Two-hybrid
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 1 1 1 Two-hybrid
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Two-hybrid
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane physical 1 1 1 Two-hybrid
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Two-hybrid
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 1 1 1 Two-hybrid
NIP100 YPL174C Large subunit of the dynactin complex physical 1 1 1 Two-hybrid
NCA2 YPR155C Protein that regulates expression of Fo-F1 ATP synthase subunits physical 1 1 1 Two-hybrid
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
YPK1 YKL126W S/T protein kinase physical 1 1 1 Biochemical Activity
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Phenotypic Suppression
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Phenotypic Suppression
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Negative Genetic
RBD2 YPL246C Possible rhomboid protease genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Phenotypic Suppression