BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
12 |
5 |
8 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
5 |
3 |
3 |
Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
physical |
4 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
physical |
4 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
BSC5 |
YNR069C |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression |
YNR068C |
YNR068C |
Putative protein of unknown function |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YGR273C |
YGR273C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEP3 |
YPR138C |
Ammonium permease of high capacity and low affinity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
LCD1 |
YDR499W |
Essential protein required for the DNA integrity checkpoint pathways |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Reconstituted Complex |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARA1 |
YBR149W |
NADP+ dependent arabinose dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO9 |
YHR137W |
Aromatic aminotransferase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BSC6 |
YOL137W |
Protein of unknown function with 8 putative transmembrane segments |
genetic |
1 |
1 |
1 |
Positive Genetic |
UPC2 |
YDR213W |
Sterol regulatory element binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRM1 |
YOR201C |
Ribose methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPM2 |
YML091C |
Protein subunit of mitochondrial RNase P |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
physical |
1 |
1 |
1 |
Two-hybrid |
GTA1 |
YEL043W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
1 |
1 |
1 |
Two-hybrid |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
DSC3 |
YOR223W |
Subunit of the DSC ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
INO80 |
YGL150C |
Nucleosome spacing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GDE1 |
YPL110C |
Glycerophosphocholine (GroPCho) phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRS120 |
YDR407C |
Component of transport protein particle (TRAPP) complex II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIP2 |
YLR129W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP2 |
YCR057C |
Conserved 90S pre-ribosomal component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN2 |
YIL075C |
Subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNN1 |
YER001W |
Alpha-1,3-mannosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK27 |
YOL136C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK5 |
YBR142W |
Essential nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HCA4 |
YJL033W |
DEAD box RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC4 |
YPR144C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ROG1 |
YGL144C |
Lipase with specificity for monoacylglycerol |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYC2 |
YBR218C |
Pyruvate carboxylase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIM1 |
YDR317W |
Protein of unknown function involved in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NAT5 |
YOR253W |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL9 |
YGR220C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPO22 |
YIL073C |
Meiosis-specific protein essential for chromosome synapsis |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
DUG3 |
YNL191W |
Component of glutamine amidotransferase (GATase II) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH3 |
YCR092C |
Mismatch repair protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR1 |
YDR368W |
NADPH-dependent aldo-keto reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX41 |
YDR425W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUP2 |
YGL166W |
Copper-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPH1 |
YIL103W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOH1 |
YJL171C |
GPI-anchored cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAN1 |
YJR150C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGT1 |
YKL038W |
Glucose-responsive transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OAF3 |
YKR064W |
Putative transcriptional repressor with Zn(2)-Cys(6) finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR162W |
YLR162W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUN1 |
YLR414C |
Plasma membrane protein with a role in cell wall integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR067C |
YGR067C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR244W |
YMR244W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL040W |
YNL040W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX6 |
YNL329C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNR065C |
YNR065C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS10 |
YNR075W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC8 |
YOL017W |
Protein involved in telomeric and mating-type locus silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL038C-A |
YOL038C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBA1 |
YOL070C |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
YVC1 |
YOR087W |
Vacuolar cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
HER1 |
YOR227W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR114W |
YPR114W |
Protein distantly similar to ceramide synthases, Lag1p and Lac1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCD6 |
YPR129W |
Repressor of translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD25 |
YER014C-A |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |