Standard name Systematic name Name description Description
NOP7 YGR103W Component of several different pre-ribosomal particles Component of several different pre-ribosomal particles; forms a complex with Ytm1p and Erb1p that is required for maturation of the large ribosomal subunit; required for exit from G0 and the initiation of cell proliferation
Visualize the interactome of NOP7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.113 0.099 NaN
Nucleolus 0.625 0.583 0.623
Nucleus 0.395 0.346 0.396
Cytoplasm NaN 0.064 NaN
Vac/Vac Memb NaN 0.053 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleolus, nucleus 4530

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NOP7 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 20 4 15 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
NOG1 YPL093W Putative GTPase physical 19 2 15 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 19 2 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 15 2 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 14 3 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 14 2 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOG2 YNR053C Putative GTPase physical 14 2 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 11 2 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 11 2 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 9 2 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NSA2 YER126C Protein constituent of 66S pre-ribosomal particles physical 9 2 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 8 2 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 8 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly physical 8 2 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
NSA1 YGL111W Constituent of 66S pre-ribosomal particles physical 8 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
CIC1 YHR052W Essential protein that interacts with proteasome components physical 7 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-Western
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 7 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 7 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 7 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 6 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
NOP15 YNL110C Constituent of 66S pre-ribosomal particles physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SDA1 YGR245C Protein required for actin organization and passage through Start physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 5 2 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 5 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 5 3 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
NOP7 YGR103W Component of several different pre-ribosomal particles physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
BRX1 YOL077C Nucleolar protein physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOP2 YNL061W rRNA m5C methyltransferase physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
NOC2 YOR206W Protein involved in ribosome biogenesis physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 3 3 3 Two-hybrid, Co-purification, Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOP4 YPL043W Nucleolar protein physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SPB1 YCL054W AdoMet-dependent methyltransferase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 3 3 2 Affinity Capture-MS, Co-purification, Co-crystal Structure
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
ERG3 YLR056W C-5 sterol desaturase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NOG1 YPL093W Putative GTPase genetic 2 2 2 Dosage Rescue, Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Lethality, Positive Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
KAP95 YLR347C Karyopherin beta physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
ORC3 YLL004W Subunit of the origin recognition complex (ORC) physical 2 2 1 Reconstituted Complex, Co-purification
ERB1 YMR049C Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins genetic 2 1 1 Negative Genetic, Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 1 1 Negative Genetic, Negative Genetic
RPL33A YPL143W Ribosomal 60S subunit protein L33A genetic 2 1 1 Dosage Rescue, Dosage Rescue
UTP15 YMR093W Nucleolar protein genetic 2 1 1 Positive Genetic, Positive Genetic
STB5 YHR178W Transcription factor genetic 2 1 1 Negative Genetic, Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 2 1 1 Negative Genetic, Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 2 1 1 Negative Genetic, Negative Genetic
NOG2 YNR053C Putative GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 2 1 1 Negative Genetic, Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 1 1 Positive Genetic, Positive Genetic
MAK5 YBR142W Essential nucleolar protein genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NOP16 YER002W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
NOP4 YPL043W Nucleolar protein genetic 1 1 1 Negative Genetic
RRF1 YHR038W Mitochondrial ribosome recycling factor physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
TIF5 YPR041W Translation initiation factor eIF5 physical 1 1 1 Affinity Capture-MS
RRP15 YPR143W Nucleolar protein physical 1 1 1 Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
YVH1 YIR026C Dual specificity protein phosphatase physical 1 1 1 Two-hybrid
YVH1 YIR026C Dual specificity protein phosphatase genetic 1 1 1 Dosage Rescue
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Affinity Capture-MS
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
RPL23B YER117W Ribosomal 60S subunit protein L23B physical 1 1 1 Affinity Capture-MS
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 1 1 1 Affinity Capture-MS
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Co-purification
YGR067C YGR067C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SOP4 YJL192C ER-membrane protein physical 1 1 1 Affinity Capture-MS
NTE1 YML059C Serine esterase physical 1 1 1 Affinity Capture-MS
PDS5 YMR076C Cohesion maintenance factor physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p physical 1 1 1 Affinity Capture-Western
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 PCA
RIX7 YLL034C Putative ATPase of the AAA family physical 1 1 1 Affinity Capture-Western
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Affinity Capture-Western
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RPM2 YML091C Protein subunit of mitochondrial RNase P physical 1 1 1 Reconstituted Complex
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 1 1 1 Synthetic Lethality
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Affinity Capture-MS
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Affinity Capture-Western
RPL25 YOL127W Ribosomal 60S subunit protein L25 genetic 1 1 1 Synthetic Growth Defect
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Positive Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Positive Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Affinity Capture-MS
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Positive Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin genetic 1 1 1 Synthetic Lethality
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Co-purification
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Positive Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Positive Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
ELA1 YNL230C Elongin A physical 1 1 1 Affinity Capture-MS
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p physical 1 1 1 Affinity Capture-MS
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) physical 1 1 1 Affinity Capture-MS
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Positive Genetic
MSS1 YMR023C Mitochondrial protein physical 1 1 1 Affinity Capture-MS
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Negative Genetic
MRP35 YNL122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-Western
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA physical 1 1 1 Affinity Capture-MS
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
DAL4 YIR028W Allantoin permease genetic 1 1 1 Positive Genetic
ICT1 YLR099C Lysophosphatidic acid acyltransferase genetic 1 1 1 Negative Genetic