Standard name Systematic name Name description Description
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors Protein involved in methylation of tRNA, rRNA, and translation factors; also involved in ribosome biogenesis; subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; N7-methylates G1575 of 18S rRNA as complex with Bud23p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; relative distribution to the nucleus increases upon DNA replication stress; functional homolog of human TRMT112
Visualize the interactome of TRM112
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.979 0.99 0.981

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TRM112 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TRM9 YML014W tRNA methyltransferase physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
BUD23 YCR047C Ribosome biogenesis factor physical 8 6 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Co-fractionation
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 7 3 6 Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOP2 YNL061W rRNA m5C methyltransferase physical 3 2 2 Affinity Capture-MS, Co-fractionation, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Co-fractionation
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 1 1 1 Affinity Capture-MS
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 Affinity Capture-MS
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
TRM1 YDR120C tRNA methyltransferase physical 1 1 1 Affinity Capture-MS
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
TRM12 YML005W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-Western
YPK3 YBR028C AGC kinase physical 1 1 1 Reconstituted Complex
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Synthetic Rescue
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 PCA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Reconstituted Complex
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) physical 1 1 1 Reconstituted Complex
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Reconstituted Complex
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Reconstituted Complex
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Reconstituted Complex
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Reconstituted Complex
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPP2A YOL039W Ribosomal protein P2 alpha physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA