PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
SNX41 |
YDR425W |
Sorting nexin |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
SLK19 |
YOR195W |
Kinetochore-associated protein |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB2 |
YIL063C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUS4 |
YNL292W |
Pseudouridine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
PAM1 |
YDR251W |
Essential protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Two-hybrid |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
physical |
1 |
1 |
1 |
Two-hybrid |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
SAE3 |
YHR079C-A |
Meiosis-specific protein involved in meiotic recombination |
physical |
1 |
1 |
1 |
Two-hybrid |
LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
1 |
1 |
1 |
Two-hybrid |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
physical |
1 |
1 |
1 |
Two-hybrid |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
physical |
1 |
1 |
1 |
Two-hybrid |
SVL3 |
YPL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Two-hybrid |
GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
YAP7 |
YOL028C |
Transcriptional repressor of nitric oxide oxidase |
physical |
1 |
1 |
1 |
Two-hybrid |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
physical |
1 |
1 |
1 |
Two-hybrid |
ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC2 |
YOR222W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFC1 |
YJR095W |
Mitochondrial succinate-fumarate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP2 |
YER090W |
Anthranilate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
IAH1 |
YOR126C |
Isoamyl acetate-hydrolyzing esterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRT1 |
YOR071C |
High-affinity nicotinamide riboside transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUP2 |
YPL189W |
Probable membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM11 |
YDR322C-A |
Subunit e of mitochondrial F1F0-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMP1 |
YLL061W |
High-affinity S-methylmethionine permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG12 |
YMR208W |
Mevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET13 |
YGL125W |
Major isozyme of methylenetetrahydrofolate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX3 |
YCR083W |
Mitochondrial thioredoxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
IDP2 |
YLR174W |
Cytosolic NADP-specific isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG1 |
YGR175C |
Squalene epoxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYK2 |
YOR347C |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD32 |
YGR262C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASN1 |
YPR145W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
COQ8 |
YGL119W |
ATPase required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASP3-3 |
YLR158C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |