GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
RUD3	YOR216C	Golgi matrix protein	genetic	7	2	6	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
GET2	YER083C	Subunit of the GET complex	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS7	YMR272C	Sphingolipid alpha-hydroxylase	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1	YLR039C	Protein involved in retrograde transport to the cis-Golgi network	genetic	5	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
MTC1	YJL123C	Protein of unknown function that may interact with ribosomes	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MNN11	YJL183W	Subunit of a Golgi mannosyltransferase complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
GOS1	YHL031C	v-SNARE protein involved in Golgi transport	genetic	3	2	2	Synthetic Rescue, Dosage Growth Defect, Dosage Growth Defect
SPC19	YDR201W	Essential subunit of the Dam1 complex (aka DASH complex)	physical	3	1	2	Two-hybrid, Two-hybrid, Two-hybrid
PMR1	YGL167C	High affinity Ca2+/Mn2+ P-type ATPase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PGA3	YML125C	Putative cytochrome b5 reductase, localized to the plasma membrane	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
RGP1	YDR137W	Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p)	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
SPC72	YAL047C	Gamma-tubulin small complex (gamma-TuSC) receptor	physical	3	2	1	PCA, Two-hybrid, Two-hybrid
ATG11	YPR049C	Adapter protein for pexophagy and the Cvt targeting pathway	physical	2	2	2	Two-hybrid, Affinity Capture-MS
COY1	YKL179C	Golgi membrane protein with similarity to mammalian CASP	physical	2	2	2	Two-hybrid, Reconstituted Complex
BOS1	YLR078C	v-SNARE (vesicle specific SNAP receptor)	genetic	2	1	2	Negative Genetic, Negative Genetic
PBS2	YJL128C	MAP kinase kinase of the HOG signaling pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
CPR7	YJR032W	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	2	1	2	Negative Genetic, Negative Genetic
MYO1	YHR023W	Type II myosin heavy chain	physical	2	2	1	FRET, Two-hybrid
RUD3	YOR216C	Golgi matrix protein	physical	2	2	1	FRET, Two-hybrid
RPT5	YOR117W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	2	2	1	PCA, Two-hybrid
YAP5	YIR018W	Basic leucine zipper (bZIP) iron-sensing transcription factor	physical	2	2	1	PCA, Two-hybrid
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	physical	2	1	1	Two-hybrid, Two-hybrid
TSC11	YER093C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p)	physical	2	1	1	Two-hybrid, Two-hybrid
SPC105	YGL093W	Subunit of a kinetochore-microtubule binding complex	physical	2	1	1	Two-hybrid, Two-hybrid
SMY1	YKL079W	Kinesin-like myosin passenger-protein	physical	2	1	1	Two-hybrid, Two-hybrid
YAP7	YOL028C	Transcriptional repressor of nitric oxide oxidase	physical	2	1	1	Two-hybrid, Two-hybrid
NIP100	YPL174C	Large subunit of the dynactin complex	physical	2	1	1	Two-hybrid, Two-hybrid
TGL1	YKL140W	Steryl ester hydrolase	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC66	YBR171W	Non-essential subunit of Sec63 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPT6	YGR116W	Nucleosome remodeling protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CST6	YIL036W	Basic leucine zipper (bZIP) transcription factor from ATF/CREB family	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
UGA3	YDL170W	Transcriptional activator for GABA-dependent induction of GABA genes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YHP1	YDR451C	Homeobox transcriptional repressor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
BMS1	YPL217C	GTPase required for ribosomal subunit synthesis and rRNA processing	physical	1	1	1	Two-hybrid
ATG14	YBR128C	Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I	physical	1	1	1	Affinity Capture-MS
APL3	YBL037W	Alpha-adaptin	physical	1	1	1	Two-hybrid
BDF1	YLR399C	BET family transcriptional regulator	physical	1	1	1	Two-hybrid
CDC3	YLR314C	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Two-hybrid
COG3	YER157W	Essential component of the conserved oligomeric Golgi complex	physical	1	1	1	Reconstituted Complex
COG3	YER157W	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Negative Genetic
ATG9	YDL149W	Transmembrane protein involved in forming Cvt and autophagic vesicles	physical	1	1	1	Affinity Capture-MS
ARE1	YCR048W	Acyl-CoA:sterol acyltransferase	physical	1	1	1	Two-hybrid
CIK1	YMR198W	Kinesin-associated protein	physical	1	1	1	Two-hybrid
BIR1	YJR089W	Subunit of chromosomal passenger complex (CPC)	genetic	1	1	1	Positive Genetic
ATG1	YGL180W	Protein serine/threonine kinase	physical	1	1	1	Two-hybrid
ATG13	YPR185W	Regulatory subunit of the Atg1p signaling complex	physical	1	1	1	Affinity Capture-MS
COG2	YGR120C	Essential component of the conserved oligomeric Golgi complex	physical	1	1	1	Reconstituted Complex
COG2	YGR120C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Negative Genetic
ATG27	YJL178C	Type I membrane protein involved in autophagy and the Cvt pathway	physical	1	1	1	Affinity Capture-MS
BLI1	YKL061W	Subunit of the BLOC-1 complex involved in endosomal maturation	physical	1	1	1	Two-hybrid
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	physical	1	1	1	Reconstituted Complex
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Negative Genetic
COG1	YGL223C	Essential component of the conserved oligomeric Golgi complex	physical	1	1	1	Reconstituted Complex
ATG23	YLR431C	Peripheral membrane protein required for autophagy and CVT	physical	1	1	1	Affinity Capture-MS
ATG8	YBL078C	Ub-like protein	physical	1	1	1	Affinity Capture-MS
BFR1	YOR198C	Component of mRNP complexes associated with polyribosomes	physical	1	1	1	Two-hybrid
CNM67	YNL225C	Component of the spindle pole body outer plaque	physical	1	1	1	Two-hybrid
ATG2	YNL242W	Peripheral membrane protein required for autophagic vesicle formation	physical	1	1	1	Affinity Capture-MS
BBP1	YPL255W	Protein required for the spindle pole body (SPB) duplication	physical	1	1	1	Two-hybrid
RPC53	YDL150W	RNA polymerase III subunit C53	physical	1	1	1	Affinity Capture-MS
KIN3	YAR018C	Nonessential serine/threonine protein kinase	physical	1	1	1	Two-hybrid
PKC1	YBL105C	Protein serine/threonine kinase	physical	1	1	1	Two-hybrid
MUM2	YBR057C	Protein essential for meiotic DNA replication and sporulation	physical	1	1	1	Two-hybrid
YSW1	YBR148W	Protein required for normal prospore membrane formation	physical	1	1	1	Two-hybrid
DIA4	YHR011W	Probable mitochondrial seryl-tRNA synthetase	physical	1	1	1	Two-hybrid
MDV1	YJL112W	Peripheral protein of cytosolic face of mitochondrial outer membrane	physical	1	1	1	Two-hybrid
GCN20	YFR009W	Positive regulator of the Gcn2p kinase activity	physical	1	1	1	Two-hybrid
MPS2	YGL075C	Essential membrane protein localized at nuclear envelope and SPBs	physical	1	1	1	Two-hybrid
SPR3	YGR059W	Sporulation-specific homolog of the CDC3/10/11/12 family of genes	physical	1	1	1	Two-hybrid
LAM4	YHR080C	Sterol-binding protein that localizes to puncta in the cortical ER	physical	1	1	1	Two-hybrid
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	physical	1	1	1	Two-hybrid
REC107	YJR021C	Protein involved in early stages of meiotic recombination	physical	1	1	1	Two-hybrid
LHS1	YKL073W	Molecular chaperone of the endoplasmic reticulum lumen	physical	1	1	1	Two-hybrid
SSA3	YBL075C	ATPase involved in protein folding and the response to stress	physical	1	1	1	Two-hybrid
SPP381	YBR152W	mRNA splicing factor, component of U4/U6.U5 tri-snRNP	physical	1	1	1	Two-hybrid
RGD1	YBR260C	GTPase-activating protein (RhoGAP) for Rho3p and Rho4p	physical	1	1	1	Two-hybrid
NHP10	YDL002C	Non-essential INO80 chromatin remodeling complex subunit	physical	1	1	1	Two-hybrid
YET3	YDL072C	Protein of unknown function	physical	1	1	1	Two-hybrid
INH1	YDL181W	Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase	physical	1	1	1	Two-hybrid
SES1	YDR023W	Cytosolic seryl-tRNA synthetase	physical	1	1	1	Two-hybrid
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	physical	1	1	1	Two-hybrid
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Negative Genetic
NGG1	YDR176W	Subunit of chromatin modifying histone acetyltransferase complexes	physical	1	1	1	Two-hybrid
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	physical	1	1	1	Two-hybrid
PEP7	YDR323C	Adaptor protein involved in vesicle-mediated vacuolar protein sorting	physical	1	1	1	Two-hybrid
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	physical	1	1	1	Two-hybrid
RRP17	YDR412W	5' exoribonuclease required for 5' end processing of pre-60S rRNA	physical	1	1	1	Two-hybrid
GCN4	YEL009C	bZIP transcriptional activator of amino acid biosynthetic genes	physical	1	1	1	Two-hybrid
GTA1	YEL043W	Protein of unknown function	physical	1	1	1	Two-hybrid
PEA2	YER149C	Coiled-coil 12S polarisome subunit	physical	1	1	1	Two-hybrid
SEC9	YGR009C	t-SNARE protein required for secretory vesicle-plasma membrane fusion	physical	1	1	1	Two-hybrid
NNF2	YGR089W	Protein that exhibits physical and genetic interactions with Rpb8p	physical	1	1	1	Two-hybrid
ENP2	YGR145W	Component of the SSU	physical	1	1	1	Two-hybrid
YTA7	YGR270W	Chromatin-binding ATPase that regulates histone gene expression	physical	1	1	1	Two-hybrid
TAF1	YGR274C	TFIID subunit, involved in RNA pol II transcription initiation	physical	1	1	1	Two-hybrid
KEL1	YHR158C	Protein required for proper cell fusion and cell morphology	physical	1	1	1	Two-hybrid
SKN7	YHR206W	Nuclear response regulator and transcription factor	physical	1	1	1	Two-hybrid
KAR2	YJL034W	ATPase involved in protein import into the ER	physical	1	1	1	Two-hybrid
SNX4	YJL036W	Sorting nexin	physical	1	1	1	Two-hybrid
NET1	YJL076W	Core subunit of the RENT complex	physical	1	1	1	Two-hybrid
SWE1	YJL187C	Protein kinase that regulates the G2/M transition	physical	1	1	1	Two-hybrid
NNF1	YJR112W	Essential component of the outer kinetochore MIND complex	physical	1	1	1	Two-hybrid
SGM1	YJR134C	Protein of unknown function	physical	1	1	1	Two-hybrid
SGM1	YJR134C	Protein of unknown function	genetic	1	1	1	Synthetic Lethality
DID4	YKL002W	Class E Vps protein of the ESCRT-III complex	physical	1	1	1	Two-hybrid
STB6	YKL072W	Protein that binds Sin3p in a two-hybrid assay	physical	1	1	1	Two-hybrid
RSM22	YKL155C	Mitochondrial ribosomal protein of the small subunit	physical	1	1	1	Two-hybrid
DID2	YKR035W-A	Class E protein of the vacuolar protein-sorting (Vps) pathway	physical	1	1	1	Two-hybrid
NOC3	YLR002C	Subunit of a nuclear complex with Noc2p and pre-replicative complexes	physical	1	1	1	Two-hybrid
SNF7	YLR025W	One of four subunits of the ESCRT-III complex	physical	1	1	1	Two-hybrid
YLR031W	YLR031W	Putative protein of unknown function	physical	1	1	1	Two-hybrid
REA1	YLR106C	Huge dynein-related AAA-type ATPase (midasin)	physical	1	1	1	Two-hybrid
VTA1	YLR181C	Multivesicular body (MVB) protein	physical	1	1	1	Two-hybrid
FAR10	YLR238W	Protein involved in recovery from arrest in response to pheromone	physical	1	1	1	Two-hybrid
FMP27	YLR454W	Protein with structural similarity to lipid transport protein Vps13p	physical	1	1	1	Two-hybrid
SUB1	YMR039C	Transcriptional regulator	physical	1	1	1	Two-hybrid
FAR3	YMR052W	Protein of unknown function	physical	1	1	1	Two-hybrid
VPS20	YMR077C	Myristoylated subunit of the ESCRT-III complex	physical	1	1	1	Two-hybrid
NIP1	YMR309C	eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3)	physical	1	1	1	Two-hybrid
MET4	YNL103W	Leucine-zipper transcriptional activator	physical	1	1	1	Two-hybrid
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	physical	1	1	1	Two-hybrid
IPI3	YNL182C	Component of the Rix1 complex and pre-replicative complexes (pre-RCs)	physical	1	1	1	Two-hybrid
JJJ1	YNL227C	Co-chaperone that stimulates the ATPase activity of Ssa1p	physical	1	1	1	Two-hybrid
VPS5	YOR069W	Nexin-1 homolog	physical	1	1	1	Two-hybrid
SGO1	YOR073W	Component of the spindle checkpoint	physical	1	1	1	Two-hybrid
ULS1	YOR191W	Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL)	physical	1	1	1	Two-hybrid
RBL2	YOR265W	Protein involved in microtubule morphogenesis	physical	1	1	1	Two-hybrid
TEA1	YOR337W	Ty1 enhancer activator involved in Ty enhancer-mediated transcription	physical	1	1	1	Two-hybrid
RQC2	YPL009C	Component of the Ribosome Quality Control (RQC) complex	physical	1	1	1	Two-hybrid
SVL3	YPL032C	Protein of unknown function	physical	1	1	1	Two-hybrid
NOP53	YPL146C	Nucleolar protein	physical	1	1	1	Two-hybrid
YPL216W	YPL216W	Putative protein of unknown function	physical	1	1	1	Two-hybrid
MAD1	YGL086W	Coiled-coil protein involved in spindle-assembly checkpoint	physical	1	1	1	Two-hybrid
NUF2	YOL069W	Component of the kinetochore-associated Ndc80 complex	physical	1	1	1	Two-hybrid
MPC54	YOR177C	Component of the meiotic outer plaque	physical	1	1	1	Two-hybrid
YTA6	YPL074W	Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family	physical	1	1	1	Two-hybrid
GYP5	YPL249C	GTPase-activating protein (GAP) for yeast Rab family members	physical	1	1	1	Two-hybrid
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	physical	1	1	1	Two-hybrid
TYE7	YOR344C	Serine-rich protein that contains a bHLH DNA binding motif	physical	1	1	1	Two-hybrid
CTF19	YPL018W	Outer kinetochore protein, needed for accurate chromosome segregation	physical	1	1	1	Two-hybrid
VPS30	YPL120W	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II	physical	1	1	1	Affinity Capture-MS
VPS15	YBR097W	Serine/threonine protein kinase involved in vacuolar protein sorting	physical	1	1	1	Affinity Capture-MS
SEC23	YPR181C	GTPase-activating protein, stimulates the GTPase activity of Sar1p	physical	1	1	1	Affinity Capture-MS
SEC13	YLR208W	Structural component of 3 complexes	physical	1	1	1	Affinity Capture-MS
SEC24	YIL109C	Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat	physical	1	1	1	Affinity Capture-MS
VPS34	YLR240W	Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate	physical	1	1	1	Affinity Capture-MS
PUF3	YLL013C	Protein of the mitochondrial outer surface	physical	1	1	1	Affinity Capture-RNA
PUF2	YPR042C	PUF family mRNA-binding protein	physical	1	1	1	Affinity Capture-RNA
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
SED5	YLR026C	cis-Golgi t-SNARE syntaxin	physical	1	1	1	Reconstituted Complex
MLH3	YPL164C	Protein involved in DNA mismatch repair and meiotic recombination	physical	1	1	1	Affinity Capture-MS
GET1	YGL020C	Subunit of the GET complex	genetic	1	1	1	Negative Genetic
YHC1	YLR298C	Component of the U1 snRNP complex required for pre-mRNA splicing	genetic	1	1	1	Negative Genetic
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Synthetic Growth Defect
VOA1	YGR106C	ER protein that functions in assembly of the V0 sector of V-ATPase	genetic	1	1	1	Synthetic Growth Defect
VPH2	YKL119C	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Positive Genetic
YPT6	YLR262C	Rab family GTPase	genetic	1	1	1	Positive Genetic
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	1	1	1	Negative Genetic
VMA11	YPL234C	Vacuolar ATPase V0 domain subunit c'	genetic	1	1	1	Positive Genetic
EST1	YLR233C	TLC1 RNA-associated factor involved in telomere length regulation	genetic	1	1	1	Synthetic Growth Defect
RPT3	YDR394W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	1	1	1	Negative Genetic
TLG1	YDR468C	Essential t-SNARE that mediates fusion of vesicles with the late Golgi	genetic	1	1	1	Negative Genetic
TAF9	YMR236W	Subunit (17 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Negative Genetic
FLC2	YAL053W	Putative calcium channel involved in calcium release under hypotonic	genetic	1	1	1	Negative Genetic
YIL152W	YIL152W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
ASF2	YDL197C	Anti-silencing protein	physical	1	1	1	Two-hybrid
ARR1	YPR199C	Transcriptional activator of the basic leucine zipper (bZIP) family	physical	1	1	1	Two-hybrid
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	1	1	1	Negative Genetic