Standard name Systematic name Name description Description
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane Peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication
Visualize the interactome of MDV1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.088 NaN 0.066
Mito 0.774 0.893 0.856
Vac/Vac Memb 0.377 0.270 0.162
Nucleolus NaN 0.056 NaN
Cytoplasm NaN NaN 0.052
Nuc Periphery NaN NaN 0.057

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 3730

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MDV1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 22 6 11 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-localization, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Two-hybrid, Affinity Capture-Western, Co-localization, Two-hybrid, Co-crystal Structure, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 19 4 12 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Co-localization, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane physical 7 3 6 Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Co-purification, Two-hybrid, Affinity Capture-Western
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 5 2 4 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 5 1 4 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 4 2 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 4 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement
LDB18 YLL049W Component of the dynactin complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex physical 4 3 2 Two-hybrid, Two-hybrid, Affinity Capture-Western, Co-localization
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 3 2 2 Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement
JNM1 YMR294W Component of the yeast dynactin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 2 2 2 Two-hybrid, Affinity Capture-RNA
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 2 Negative Genetic, Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RAD30 YDR419W DNA polymerase eta genetic 2 1 2 Negative Genetic, Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 2 1 2 Negative Genetic, Negative Genetic
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme physical 2 2 1 Two-hybrid, Affinity Capture-Western
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CCM1 YGR150C Mitochondrial 15S rRNA-binding protein physical 1 1 1 Two-hybrid
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 PCA
HYM1 YKL189W Component of the RAM signaling network physical 1 1 1 Two-hybrid
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen physical 1 1 1 Two-hybrid
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 1 1 1 Two-hybrid
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Positive Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 1 1 1 Two-hybrid
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing physical 1 1 1 Two-hybrid
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Two-hybrid
MRP4 YHL004W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Two-hybrid
YIL152W YIL152W Putative protein of unknown function physical 1 1 1 Two-hybrid
MRX12 YJR003C Protein that associates with mitochondrial ribosome physical 1 1 1 Two-hybrid
TAH11 YJR046W DNA replication licensing factor physical 1 1 1 Two-hybrid
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 PCA
SWC3 YAL011W Protein of unknown function physical 1 1 1 Two-hybrid
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Two-hybrid
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor physical 1 1 1 Two-hybrid
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Two-hybrid
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
YLR031W YLR031W Putative protein of unknown function physical 1 1 1 Two-hybrid
UBI4 YLL039C Ubiquitin physical 1 1 1 Reconstituted Complex
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Phenotypic Enhancement
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Phenotypic Enhancement
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
PGA1 YNL158W Essential component of GPI-mannosyltransferase II genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Negative Genetic
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR062C YOR062C Protein of unknown function genetic 1 1 1 Negative Genetic
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Negative Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Two-hybrid
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Negative Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Positive Genetic
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family physical 1 1 1 Two-hybrid
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits genetic 1 1 1 Negative Genetic
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Negative Genetic