Standard name Systematic name Name description Description
BIT61 YJL058C Subunit of TORC2 membrane-associated complex Subunit of TORC2 membrane-associated complex; involved in regulation of cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity; BIT61 has a paralog, BIT2, that arose from the whole genome duplication
Visualize the interactome of BIT61
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.073 0.100 0.087
Cytoplasm 0.917 0.938 0.904
Mito 0.104 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1960

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
BIT61 0 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 4 3 4 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-localization
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 4 3 3 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
ROG3 YFR022W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 2 1 2 Negative Genetic, Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 2 Negative Genetic, Negative Genetic
OSW2 YLR054C Protein of unknown function reputedly involved in spore wall assembly genetic 2 1 2 Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 2 1 2 Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 2 1 2 Negative Genetic, Negative Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 1 Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 2 1 1 Negative Genetic, Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 2 1 1 Negative Genetic, Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AVO1 YOL078W Component of the membrane-bound TORC2 complex physical 1 1 1 Reconstituted Complex
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
ADA2 YDR448W Transcription coactivator physical 1 1 1 Two-hybrid
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
MET30 YIL046W F-box protein containing five copies of the WD40 motif physical 1 1 1 Two-hybrid
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Two-hybrid
LST8 YNL006W Protein required for the transport of Gap1p physical 1 1 1 Affinity Capture-MS
ENV11 YGR071C Protein proposed to be involved in vacuolar functions physical 1 1 1 Two-hybrid
TAF13 YML098W TFIID subunit (19 kDa) physical 1 1 1 Two-hybrid
YDL057W YDL057W Putative protein of unknown function physical 1 1 1 Two-hybrid
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation physical 1 1 1 Two-hybrid
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator physical 1 1 1 Two-hybrid
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 1 1 1 Two-hybrid
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) physical 1 1 1 Two-hybrid
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane physical 1 1 1 Two-hybrid
MND2 YIR025W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Two-hybrid
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
YPK2 YMR104C AGC-type S/T protein kinase physical 1 1 1 Affinity Capture-Western
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Reconstituted Complex
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Reconstituted Complex
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Reconstituted Complex
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Reconstituted Complex
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Lethality
PHO3 YBR092C Constitutively expressed acid phosphatase similar to Pho5p genetic 1 1 1 Positive Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Positive Genetic
YKL162C YKL162C Putative protein of unknown function genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
CSC1 YLR241W Calcium permeable gated cation channel genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Positive Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins physical 1 1 1 Reconstituted Complex
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Synthetic Growth Defect
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Two-hybrid