Standard name Systematic name Name description Description
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; TORC2 complex substrate and effector; SLM2 has a paralog, SLM1, that arose from the whole genome duplication
Visualize the interactome of SLM2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SLM2 0 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 9 3 9 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 3 2 3 Dosage Rescue, Dosage Rescue, Negative Genetic
CNA1 YLR433C Calcineurin A physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins physical 3 3 2 Reconstituted Complex, Affinity Capture-Western, Two-hybrid
CMP2 YML057W Calcineurin A physical 3 2 2 Two-hybrid, Two-hybrid, Reconstituted Complex
BIT2 YBR270C Subunit of TORC2 membrane-associated complex physical 2 2 2 Reconstituted Complex, Two-hybrid
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 2 2 2 Two-hybrid, Affinity Capture-Western
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 2 2 2 Dosage Rescue, Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 2 1 2 Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SPO19 YPL130W Meiosis-specific prospore protein genetic 2 1 2 Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Negative Genetic, Negative Genetic
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 2 1 1 Positive Genetic, Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
DIS3 YOL021C Exosome core complex catalytic subunit genetic 1 1 1 Negative Genetic
RRP45 YDR280W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Two-hybrid
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 1 1 1 Positive Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
GCN2 YDR283C Protein kinase physical 1 1 1 Affinity Capture-MS
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Positive Genetic
PRP31 YGR091W Splicing factor genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Rescue
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Dosage Rescue
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Positive Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Negative Genetic
HYM1 YKL189W Component of the RAM signaling network genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Dosage Rescue
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Negative Genetic
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
GRX5 YPL059W Glutathione-dependent oxidoreductase physical 1 1 1 Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Positive Genetic
PEF1 YGR058W Penta-EF-hand protein physical 1 1 1 Two-hybrid
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Positive Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Positive Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Lethality
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
NBP1 YLR457C Spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Negative Genetic
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Synthetic Rescue
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Synthetic Rescue
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Positive Genetic
SPC3 YLR066W Subunit of signal peptidase complex genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 1 1 1 Negative Genetic
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SVL3 YPL032C Protein of unknown function genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 1 1 1 Affinity Capture-MS
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Positive Genetic
HEM12 YDR047W Uroporphyrinogen decarboxylase genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 genetic 1 1 1 Positive Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Positive Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Synthetic Rescue
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
MZM1 YDR493W Protein required for assembly of the cytochrome bc(1) complex genetic 1 1 1 Negative Genetic
GIT1 YCR098C Plasma membrane permease genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic